Gene Information

Name : SC4C2.26 (SCO7691)
Accession : NP_631730.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Virulence
Product : lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : -
Position : 8528166 - 8529581 bp
Length : 1416 bp
Strand : +
Note : SC4C2.26, possible lyase, len: 471 aa; C-terminal region similar to C-terminal region of SW:TRPE_HALVO (EMBL:M83788) Halobacterium volcanii anthranilate synthase component I(EC 4.1.3.27) TrpE, 523 aa; fasta scores: opt: 545 z-score: 624.2 E(): 3.1e-27; 38

DNA sequence :
ATGAGCACCGGATCCCGGAACATCTGGGAGGCATGGGCGAGGTCCGTCCCACCACTCGTGTGCGCGAGCACCCGCGAGCC
CTGCCACGACCCGGCCGCCACCGCCACCCGCCTCGCACGGGCGGGCTTGGCGGGCCAGTACGTGGTGTACGAGTCGGAAG
GCGGGGTCTGGCACTTCGCTGCGGGCTCCGACGTCAGCGTCACCGCGGATGCCACCGGCATCACCGCGCGGGCCGCCGGG
CGTACCTGGAGCTCGCGCACGCAGCGGCGGCCGTTGACGGCGTTCGCCGACGCCCTGGCCGCGTTGCCGCCCGTGTCCGG
CTTGCCCGACGAGAGCGGCGAGGAGCGCCGCTTCTACGGCTGGGCGGCCTTCGAACTCGCCCACCTCCTGCACGCGGACC
CCGCGACGGCCGGAGACCGGCCGCTGCTGCACGCCCTGATCCCGTCCGTCGAAGTGACCCTCACCGGCGACTCGACAGTG
ATCCGCGCGGTGGACGAGGCATGGGCGCGCAAGGTCGCCGACCTGCTCGCGGAGCCCGCGGCCGAGCAGACCCCCCACGA
CGAACCGGCGCGGGACCGGACCGAGGACGTCATCGCCGTCGGTACCGCCGCCTACGGCCGAGCGGTCTCCCGCACGGTCC
GGGACATCCGCGCCGGGTTGCTGGAGAAGGCCGTCGTCTCCCGGCAGGTCCCCCTGCCCGCCGAGCCGCGCCCCGACTTC
CCCGCGACCTACCTCGCGGGCCGCCGGGCCAACACACCGGCACGTTCCTACGTGCTGGACCTCGGCGGTTACCGGGCTGC
CGGATTCAGCCCCGAGACCGTTCTCGAGGTCGAAGACGACGGGCGGGTCAGCACCCAGCCGCTCGCGGGCACGCGCGCCC
TGGGCGCCGACCCGGCGGAGAACGAGCGCCGGCGCGCGGAACTGCTCAGCGACCCCAAGGAGATACACGAACACGCCGTG
TCCGTACGTCTCGCCTGGGAGGAGATGGCGGCCGTGTGCCGTCCCGGCTCCGTGGTGGTCGAGGAGTACATGGCGGTCCG
CCCACGAGGATCGGTGCAGCACCTGGCCTCACGGGTGACGGGCCGGCTCCGGCCGGACGCCGGACCCTGGGACGCCTTCG
CCTCCCTGTTCCCCGCGATCACCGCCACCGGAGTCTCCAAACGCGCCGCGCTCCAGGCCCTGGCCCGCCACGAGGAAGGG
CCACGCGGCCTGTACGGCGGGGCGGTCTTCCGGGGCAGCACCAGCGGCGCCCTCGACGCCGCCCTCGTCCTGCGCACCCT
GATCGGCGCGGGCGACGAGGCGTGGCTGCGAGCCGGCGCCGGGGTCACCGCCCAGTCCAGCCCCGAGCGGGAGACCGAGG
AGACCTGCGAGAAACTCCGCAGCGTCGCCCCGTACCTGAGGTTCTCCCTGACCTGA

Protein sequence :
MSTGSRNIWEAWARSVPPLVCASTREPCHDPAATATRLARAGLAGQYVVYESEGGVWHFAAGSDVSVTADATGITARAAG
RTWSSRTQRRPLTAFADALAALPPVSGLPDESGEERRFYGWAAFELAHLLHADPATAGDRPLLHALIPSVEVTLTGDSTV
IRAVDEAWARKVADLLAEPAAEQTPHDEPARDRTEDVIAVGTAAYGRAVSRTVRDIRAGLLEKAVVSRQVPLPAEPRPDF
PATYLAGRRANTPARSYVLDLGGYRAAGFSPETVLEVEDDGRVSTQPLAGTRALGADPAENERRRAELLSDPKEIHEHAV
SVRLAWEEMAAVCRPGSVVVEEYMAVRPRGSVQHLASRVTGRLRPDAGPWDAFASLFPAITATGVSKRAALQALARHEEG
PRGLYGGAVFRGSTSGALDAALVLRTLIGAGDEAWLRAGAGVTAQSSPERETEETCEKLRSVAPYLRFSLT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAD17661.1 unknown Not tested HPI Protein 6e-55 47
irp9 CAB46570.1 salicylate synthetase, Irp9 Virulence HPI Protein 5e-57 45
irp9 YP_001006810.1 salicylate synthase Irp9 Not tested HPI Protein 6e-57 45
APECO1_1052 YP_853070.1 salicylate synthase Irp9 Not tested PAI IV APEC-O1 Protein 2e-57 45
ybtS YP_002346907.1 salicylate synthase Irp9 Not tested HPI Protein 2e-57 45
ybtS NP_669701.1 salicylate synthase Irp9 Not tested HPI Protein 2e-57 45
ybtS YP_070129.1 salicylate synthase Irp9 Not tested HPI Protein 2e-57 45
ybtS CAA21385.1 - Virulence HPI Protein 2e-57 45
ybtS NP_993012.1 salicylate synthase Irp9 Not tested HPI Protein 7e-57 44