Gene Information

Name : SC8G12.12 (SCO7536)
Accession : NP_631580.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Unknown
Product : hypothetical protein
Function : -
COG functional category : R : General function prediction only
COG ID : COG2409
EC number : -
Position : 8355539 - 8357758 bp
Length : 2220 bp
Strand : +
Note : SC8G12.12, possible integral membrane protein, len: 739 aa. Highly similar to many Streptomyces coelicolor membrane proteins including: TR:CAB59662(EMBL:AL132674) SCE87.17C (745 aa), fasta scores opt: 1860 z-score: 1926.0 E():0 66.5% identity in 740 aa ov

DNA sequence :
GTGGCTACGTTTCTCTATCGACTCGGCCGGAGGGCGTTCCGGCGCCGCGGCCTGGTCGCCCTGTTGTGGGTGGCCATACT
CGTGGGCGCCGGCGTCGCCTCGTCCGCCGCGCCGGCCCCGCCCGAAGACTCCTTCTCCATGCCGGGCACCGAGTCCCAGA
AGGCGTTCGACCTGCTCGACGAGCAGTTCCCGGCCGCCAGCGCCGAGGGCGCCACGGCCCGCGTCGTGATCCGTGCCCCC
GAGGGCGCGAAGATCTCCGACGCGGCCGGCAAGGACCGGGTGAAGGACCTGGTCGCCGACCTGAAGGGCGGCCCGCAGGT
CTCCTCGGTGGACGACCCGTTCGAGGCGAACGCCGTCAGCAAGGACGGCACCACCGCCTACGCCTCGGTGACCTACAAGG
TCAACGCGATGGAGCTGACCGACGAGGCCCGCGACTCGCTCACGGCCGCCACCGACGGGGCGCGCGAGGGCGGGTACACG
GTCGAGACCGGCGGCGACGCGGTCGTGGCCGAGCAGGAGATGGGCGGCACCGCCGAGCTGATCGGCATCGGCGTCGCCGC
GATCGTGCTCCTGCTGACCTTCGGCTCACTGGTCGCGGCGGGCATGCCGCTGCTCTCGGCGATCATCGGTGTCGGCATCG
GCATCTCCGCCATCGGGGCGCTCGGCAGCACCCTGGAGCTGTCCGCCACGACCTCCACCCTCGCGATGATGATCGGCCTC
GCGGTCGCCATCGACTACGCGCTGTTCATCGTCTCGCGCTACCGGGCGGAGATCTCCGAGGGTCGTGCCCCGGAGGAGGC
GGCCGGACGAGCGGTCGGCACCGCGGGCTCCGCGGTCGTCTTCGCCGGACTGACCGTCGTCGTGGCCCTGGCCGGTCTCG
CGATCGTCAACATCCCGATCCTCACCAAGATGGGCCTGGCCGCCGCGGGCACCGTCGGCATCGCCGTGCTGATCGCCCTC
ACCCTCACCCCGGCGCTGCTCGGCTTCGCCGGCAAGAGGGCGCTCAGCCGCAAGGACCGCAAGGCTCCCGCCGGGGCGCG
GGCCGCCTCCGGCAAGCCGAAGCTCGGCACCCGGTGGGCCCGCTTCGTACAGCGGCGCCCGGTCACCGTCCTGCTGACCG
CGGTCCTCGGCCTCGGCGTGATCGCCGTACCGGCCGCCGGCATGGAGCTGGGCCTGCCCGACGAGGGCAGCTCGGCCCCC
GACACCACCCAGCGCAAGGCCTACGACATGCTGTCCGAGTCCTTCGGGGCCGGGTTCAACGGCCCGCTGATGGTCACCGT
GGACGCGCGCGGCGCGGACGACCCGAAGGCCGCCGCGGACACCGTGGGCGAGAAGATCACCGGACTGGGCGAGGCCGCGG
CCGTCACCCCGGCCAACTTCAACGAGGAGGGCGACACCGCCGTCCTCACCGTGATGCCCAAGACCGGCCCGAGCGACGTC
GCCACCGAGTCGCTGGTGCACGACATCCGCTCGCTGTCCGGCGACATCAGGGCCGACACCGGCGCTGCCATGCTGGTCAC
CGGTGCGACCGCGATGACGATCGACTTCTCGCAGACCCTGGACGACGCGCTGATCCCCTACCTGGCGCTGGTCGTCGGGC
TCGCCTTCCTGCTCCTGATGCTGGTTTTCCGCTCGGTCCTCGTCCCGCTGAAGGCGGCCCTGGGCTTCCTGCTCTCGGTG
GCCGCGGCGCTCGGCGCGGTGGTCGCGGTGTTCCAGTGGGGCTGGCTCGCCGACGTGTTCGGCGTGGACCAGCCGGGCCC
GATCATGTCGATGATGCCGATCTTCATGATCGGCGTGGTCTTCGGCCTCGCCATGGACTACGAGGTCTTCCTCGTCACCC
GCATGCGGGAGGCGTACGTCCACGGAGAGTCCGCCGCCGAGTCCGTCACCACGGGCTTCACCCACGGCGGCCGGGTCGTC
GCGGCCGCCGCGATCATCATGATCAGCGTCTTCTCCGGCTTCATCCTGGAGAACGACGCCATGATCAAGATGATGGGCTT
CGGGCTCGCGATCGCGGTGCTCTTCGACGCCTTCGTGGTCCGCATGGCCATCGTGCCCGCGGTGCTCGCACTGCTCGGCA
CCAAGGCGTGGTGGCTGCCCAGGTGGCTGGACCGCGTCCTGCCGAACGTCGACGTGGAGGGCGAGAAGCTGCACCGGGAA
CTCGGCGACACCGCCGCTCCCACGGAGCCCGCCCGCGAGCCGGAGACGGCCGGAGTCTGA

Protein sequence :
MATFLYRLGRRAFRRRGLVALLWVAILVGAGVASSAAPAPPEDSFSMPGTESQKAFDLLDEQFPAASAEGATARVVIRAP
EGAKISDAAGKDRVKDLVADLKGGPQVSSVDDPFEANAVSKDGTTAYASVTYKVNAMELTDEARDSLTAATDGAREGGYT
VETGGDAVVAEQEMGGTAELIGIGVAAIVLLLTFGSLVAAGMPLLSAIIGVGIGISAIGALGSTLELSATTSTLAMMIGL
AVAIDYALFIVSRYRAEISEGRAPEEAAGRAVGTAGSAVVFAGLTVVVALAGLAIVNIPILTKMGLAAAGTVGIAVLIAL
TLTPALLGFAGKRALSRKDRKAPAGARAASGKPKLGTRWARFVQRRPVTVLLTAVLGLGVIAVPAAGMELGLPDEGSSAP
DTTQRKAYDMLSESFGAGFNGPLMVTVDARGADDPKAAADTVGEKITGLGEAAAVTPANFNEEGDTAVLTVMPKTGPSDV
ATESLVHDIRSLSGDIRADTGAAMLVTGATAMTIDFSQTLDDALIPYLALVVGLAFLLLMLVFRSVLVPLKAALGFLLSV
AAALGAVVAVFQWGWLADVFGVDQPGPIMSMMPIFMIGVVFGLAMDYEVFLVTRMREAYVHGESAAESVTTGFTHGGRVV
AAAAIIMISVFSGFILENDAMIKMMGFGLAIAVLFDAFVVRMAIVPAVLALLGTKAWWLPRWLDRVLPNVDVEGEKLHRE
LGDTAAPTEPAREPETAGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CMM_0093 YP_001220832.1 RND family transporter Not tested chp/tomA region Protein 1e-97 45
cur_1489 YP_001800883.1 RND superfamily drug exporter Not tested Not named Protein 1e-87 41