Gene Information

Name : SC8G12.09 (SCO7533)
Accession : NP_631577.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Virulence
Product : two-component system response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 8352526 - 8353227 bp
Length : 702 bp
Strand : +
Note : SC8G12.09, two-component system response regulator protein, len: 233 aa. Highly similar to many response regulators including: Amycolatopsis mediterranei TR:CAB82846(EMBL:AJ277082) response regulator (229 aa), fasta scores opt: 937 z-score: 1114.4 E(): 0

DNA sequence : 
ATGGCACGAGTCCTGCTCATCGAAGACGACCCCGCGGTGCAGAGAGGCGTCTCGCTCGCGCTGAAACGCCGGGGGCACGA
GGTGGCGGTCGCGGGCAGCGGGGAGACCGGCCTGCTGACGCTGGAGCGGCACCGGCCCGACCTGGTGCTCCTCGACCTGA
TGCTGCCGAACATGAGCGGTCTGGAGGTGTGCCGCCGGATCCGGGAGAGCAAACGGATCCCGATCATCATCCTCTCCGCG
CGGGGCGACGAGATCGACATGGTCGTCGGCCTGGAGGCGGGCGCCGACGACTACATCGTCAAACCGGCGGGCGCCGAGCT
GCTGGAGGCGCGGATCAGAGCGGTCCTGCGCCGGGTCGCGCCCGCCCAGGACGGCGGCAGCCGGGATCCGGCCGACGCCG
GCCCCGAGCGGCACGCGGACCTCACGGTGGACCGCACCACCCTGGTCGTGGCCAAGCACGGCACCGAGCTGCCCCTGGCC
CCCTCGGAACTGAAGCTCCTGCTGTTCCTCACCGCGACCCCCGGGCAGGTGTACTCGCGCCAGCAACTGCTGGAGCAGGT
CTGGGAACACTCCTTCTACGGCGACGTCCGCCTCGTCGACGCCTGCGTCATGCGGCTGCGTGCCCGTATCGAGGACGACC
CGCGCAAACCGGTGTACGTACAGACCGTGCGCGGCTTCGGCTACCGGTTCGGTCCGCTGTGA

Protein sequence : 
MARVLLIEDDPAVQRGVSLALKRRGHEVAVAGSGETGLLTLERHRPDLVLLDLMLPNMSGLEVCRRIRESKRIPIIILSA
RGDEIDMVVGLEAGADDYIVKPAGAELLEARIRAVLRRVAPAQDGGSRDPADAGPERHADLTVDRTTLVVAKHGTELPLA
PSELKLLLFLTATPGQVYSRQQLLEQVWEHSFYGDVRLVDACVMRLRARIEDDPRKPVYVQTVRGFGYRFGPL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 1e-27 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SC8G12.09 NP_631577.1 two-component system response regulator NC_012469.1.7685629. Protein 1e-40 42
SC8G12.09 NP_631577.1 two-component system response regulator HE999704.1.gene1528. Protein 4e-28 41
SC8G12.09 NP_631577.1 two-component system response regulator AE000516.2.gene3505. Protein 5e-33 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SC8G12.09 NP_631577.1 two-component system response regulator VFG1702 Protein 5e-28 41