Gene Information

Name : SCBAC25F8.15 (SCO7523)
Accession : NP_631568.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Virulence
Product : chaperone
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 8339604 - 8342117 bp
Length : 2514 bp
Strand : +
Note : SCBAC25F8.15, possible chaperone, len: 837 aa; highly similar to SW:CLPC_BACSU (EMBL:D26185) Bacillus subtilis negative regulator of genetic competence ClpC or MecB, 810 aa; fasta scores: opt: 2262 Z-score: 2131.8 bits: 405.4 E(): 3.9e-111; 50.807% identi

DNA sequence :
ATGTCGATGTCGTCGTTCGGATTCGGTGCGTCCGATCCGTTCAGTGATCTGTTCAACCGGTTCTTCGGAACGTCGCCCGC
GTCCTCGCCCCCGGCGGTGCAGCGGGTGCCGATCGGCCGGATGCTGACCGAGTCCTCGCAGGAGCTCCTCAACCTGGCGG
CACGGCGGTCGCTGGAGGACGGGACGTCCGACCTGGACACGGAGCACCTGTTGTGGGCGGCCACGAAGGTCGAGCCCGCG
CGGGGGCTGCTCGCCCGGGCGGGCGCCGACCCCGACGCGCTCGCCTCCCGGATCGCCGAGGTCCTGCCCCGCGAGGCGGG
CGAGCCGTCCGCCGAGCCGGGCCTCACCCCGGCCGCCAAGCGCACCCTCGCCACCGCCTACGCCCGCTCCCGGGCCTCCG
GCGTCTCCTACATCGGCCCCGAGCACATCCTGGGCGCCCTGCTGGCGGACGGCGACACGGGCGCGGCCCGGCTGCTGGGC
GCCCAGGGGCAGGACATCGGCAAGCTGGAGGGGCTCACCGAGCAGGCCGCCCGTCCGGGCGGGGCCCCGGGCGACGACGG
CGGGAGACCGGCCACCACGCTGGACGAGTACGGACGGGACCTGACCGACGAGGCGAAGGCCGGGAAGCTCGACCCCGTCG
TCGGCCGCGCCGAGGAGATCGAGCAGACCGTCGAGATCCTCTCCCGGCGCTCCAAGAACAATCCGGTGCTGATCGGCGAG
CCCGGCGTCGGCAAGACCGCCATCGTGGAGGGACTGGCCCAGCGCATCGTGGCCGGTGAGGTCCCGAACACGCTGAAGGA
CAAGAGGGTGGTCGCCCTCGACCTGTCCGCCATGGTGGCGGGCGCGCAGTACCGGGGCCAGTTCGAGGAGCGGCTCAAGA
AGGTCATCGAGGACGTCCAGCAGGCCCGCGGCGACATCATCCTGTTCATCGACGAACTGCACACCGTCGTCGGCGCCGGA
GCGAGCGGCGAGAGCTCCATGGATGCCGGCAACATGCTCAAGCCGGCCCTCGCGCGCGGCGAACTGCACGTGGTGGGCGC
CACGACCATCGACGAGTACCGCAAGTACGTCGAGAAGGACGCCGCCCTCGAACGCCGCTTCCAGCCCGTGATGGTCCCCG
AGCCCTCGGTCGAGGAGACGGTGCAGATCCTGGAGGGCCTGCGCGACGCCTACGAGGCGCACCACCAGGTCCGCTTCGCC
GACGGAGCGCTGACCGCGGCGGCGGAGCTGTCCGACCGCTACGTCAGCGACCGCTTCCTGCCCGACAAGGCGATCGACGT
CATGGACCAGGCGGGCGCCCGGGTACGGCTGCGCAGCGCGAGCCGTTCCACCGAGGTCGTCGGCCGCGAGGACCGCATCG
CGAAGCTGCGCCGGGAGCAGGAGCAGGCCGTCGCGGCCGAGGACTACGCCCGCGCGGGCGAGCTGAAACGCGAGATCGCC
GAGGCGGAGGGCGAACTGGCGGGCATCGAGGAGCGCCGCGAGGGCGTCGTCTCCGTCACCGCCGACGACATCGCGGACGT
GATCTCCCGCCGCACCGGCATCCCGGTCTCCCAGCTGACGGCGGGGGAGAAGGAGCGGCTGCTCAGGCTGGAGGAGGAGA
TGCACGCCCGGATCGTCGGCCAGGACGAGGCGGTCACCGCCGTCTCACGGGCCGTGCGCCGCAACCGGGCCGGCATGGGC
GACCCCGACCGCCCCGTGGGCTCCTTCCTCTTCCTCGGCCCCACCGGTGTCGGCAAGACCGAGCTGGCCAAGACCCTCGC
CGAGCTGCTGTTCGGCGAGGAGAACCGCATGATCCGCTTCGACATGAGCGAGTTCCAGGAGAAGCACACGGTCGCCCGGC
TCGTCGGCGCGCCCCCGGGCTACGTCGGCTACGAGGAGGCCGGCCAGCTCACCGAGAAGGTCCGCAGGCAGCCCTACAGC
GTGGTCCTGTTCGACGAGGTCGAGAAGGCCCACCCCGACGTCTTCAACACGCTGCTGCAGATCCTCGACGACGGCCGCCT
CACCGACGGACAGGGACGCACCGTCGACTTCCGGCACTGCGTGGTCATCATGACGTCCAACATCGGCGCCCACCGCATCC
TCGACCACAAGGGCGACGTGTCCGACCTCAAGGACGAACTCATGCAGGAGCTGCGGGGCCGGTTCCTGCCGGAGTTCCTC
AACCGCATCGACGAGATCATCGTCTTCCACGGCCTCACCGAGGACGACCTCTCGCGGATCGTGGACCACCTGCTGGCGCA
GAGCGAACGGCGGGTGCACGCCCAGGGCATGACACTGAAGGTCACCGAGGCGGCCAAGAAGCTGCTGATCGCCCACGGAC
ACCAGCCGGAGTTCGGCGCCCGACCGCTCAGGCGCACCATCCAGGCCGAACTCGACAACCGCGTCGCCGACCTGCTCCTC
GGCGGCGAGGCCGACCCCGGCGACACCATCGTCGCCGACGTGGTCGACGACTCCCTGCACTGCACGGTCGACAAGTCCGG
CACCGCACGACCCGCGGAGGCGAGCGGCACATGA

Protein sequence :
MSMSSFGFGASDPFSDLFNRFFGTSPASSPPAVQRVPIGRMLTESSQELLNLAARRSLEDGTSDLDTEHLLWAATKVEPA
RGLLARAGADPDALASRIAEVLPREAGEPSAEPGLTPAAKRTLATAYARSRASGVSYIGPEHILGALLADGDTGAARLLG
AQGQDIGKLEGLTEQAARPGGAPGDDGGRPATTLDEYGRDLTDEAKAGKLDPVVGRAEEIEQTVEILSRRSKNNPVLIGE
PGVGKTAIVEGLAQRIVAGEVPNTLKDKRVVALDLSAMVAGAQYRGQFEERLKKVIEDVQQARGDIILFIDELHTVVGAG
ASGESSMDAGNMLKPALARGELHVVGATTIDEYRKYVEKDAALERRFQPVMVPEPSVEETVQILEGLRDAYEAHHQVRFA
DGALTAAAELSDRYVSDRFLPDKAIDVMDQAGARVRLRSASRSTEVVGREDRIAKLRREQEQAVAAEDYARAGELKREIA
EAEGELAGIEERREGVVSVTADDIADVISRRTGIPVSQLTAGEKERLLRLEEEMHARIVGQDEAVTAVSRAVRRNRAGMG
DPDRPVGSFLFLGPTGVGKTELAKTLAELLFGEENRMIRFDMSEFQEKHTVARLVGAPPGYVGYEEAGQLTEKVRRQPYS
VVLFDEVEKAHPDVFNTLLQILDDGRLTDGQGRTVDFRHCVVIMTSNIGAHRILDHKGDVSDLKDELMQELRGRFLPEFL
NRIDEIIVFHGLTEDDLSRIVDHLLAQSERRVHAQGMTLKVTEAAKKLLIAHGHQPEFGARPLRRTIQAELDNRVADLLL
GGEADPGDTIVADVVDDSLHCTVDKSGTARPAEASGT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-176 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SCBAC25F8.15 NP_631568.1 chaperone VFG0080 Protein 4e-155 53
SCBAC25F8.15 NP_631568.1 chaperone VFG0079 Protein 1e-178 50