Gene Information

Name : SC3A4.01 (SCO7075)
Accession : NP_631137.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Virulence
Product : two component response regulator protein
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 7863791 - 7864483 bp
Length : 693 bp
Strand : +
Note : SC3A4.01, two component response regulator protein, len: 230 aa. Highly similar to Pseudomonas syringae (pv. tomato) SW:COPR_PSESM (EMBL:L05176) transcriptional activator of copper resistance operon, CopR (227 aa) fasta scores, opt: 549 z-score: 653.7 E()

DNA sequence : 
GTGCGAATCATGATCGCGGACGACGACGCGGCCATCCGTGCGTCACTGGAGCGGGTGCTCCAGGTCGAGGGTTACGACAC
CAGCACCGTCGCCAACGGTTTCGCCGTGCTCGACGAGGTCGGTGGGGCCGACGGTGACACTCTGGATCTGCTGCTTCTCG
ACGTGATGATGCCCCGCCTCGGCGGGTTGGAGACCTGCCGGCGATTGCGGGCCGCGGGCCGGGATCTGCCGGTGCTGATG
CTGACCGCCCGTGACCAGGTCTCCGACCGGGTCACGGGGCTGGACGCAGGTGCCGACGACTACCTGCCCAAGCCGTTCGC
CACCGAGGAGTTGCTGGCCCGGGTGCGGGCCCTGCTGCGTCGGCGCACGCCGGCCGACGAGGAGTCGCACATCCTGTCGT
TCGCCGACGTCCGGCTCGACTCCGACAGGTTCGAGGCGTGGCGGGGCAGGCGGCCACTGCACCTGACCCGGACCGAGTTC
TCCCTCCTGGAGGTCCTCTTGTGCAACGCGACCCGGGTCTTGACCCGCGACGCGCTGTTCGAGGCGATCTGGGGCTTCGG
TATGAGCTCCACCGCCAACAATCTTCAGGTTTACGTGAGCTATCTGCGCCGCAAGATGGAGGCGGAGGGTGAACCGCGAT
TGATCTACACAGTGCGTGGCCTGGGATACACGTTGCGGGAGACTCCTCCGTGA

Protein sequence : 
MRIMIADDDAAIRASLERVLQVEGYDTSTVANGFAVLDEVGGADGDTLDLLLLDVMMPRLGGLETCRRLRAAGRDLPVLM
LTARDQVSDRVTGLDAGADDYLPKPFATEELLARVRALLRRRTPADEESHILSFADVRLDSDRFEAWRGRRPLHLTRTEF
SLLEVLLCNATRVLTRDALFEAIWGFGMSSTANNLQVYVSYLRRKMEAEGEPRLIYTVRGLGYTLRETPP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-19 43
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 2e-18 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SC3A4.01 NP_631137.1 two component response regulator protein BAC0638 Protein 1e-17 46
SC3A4.01 NP_631137.1 two component response regulator protein HE999704.1.gene1528. Protein 1e-28 44
SC3A4.01 NP_631137.1 two component response regulator protein BAC0111 Protein 3e-20 44
SC3A4.01 NP_631137.1 two component response regulator protein BAC0308 Protein 5e-21 44
SC3A4.01 NP_631137.1 two component response regulator protein BAC0197 Protein 1e-17 44
SC3A4.01 NP_631137.1 two component response regulator protein BAC0347 Protein 1e-17 43
SC3A4.01 NP_631137.1 two component response regulator protein BAC0083 Protein 1e-23 42
SC3A4.01 NP_631137.1 two component response regulator protein BAC0125 Protein 1e-18 41
SC3A4.01 NP_631137.1 two component response regulator protein NC_002516.2.879194.p Protein 7e-15 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SC3A4.01 NP_631137.1 two component response regulator protein VFG1390 Protein 5e-49 59
SC3A4.01 NP_631137.1 two component response regulator protein VFG0473 Protein 4e-20 45
SC3A4.01 NP_631137.1 two component response regulator protein VFG1389 Protein 3e-29 44
SC3A4.01 NP_631137.1 two component response regulator protein VFG1386 Protein 5e-32 43
SC3A4.01 NP_631137.1 two component response regulator protein VFG0596 Protein 7e-20 43