Gene Information

Name : tktB (SCO6663)
Accession : NP_630738.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 7400592 - 7402688 bp
Length : 2097 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAGCACGCAGTCGAGCAAGCAGACAGTGGACGGCGCGGACCGCTTCGAATGGACCGAACTCGACCGGCGTGCCGTGGA
CACCGCCCGGATCCTGGCGGCCGACGCCGTGCAGAAGGTGGGCAACGGTCACCCGGGTACGGCGATGGCCCTCGCCCCGG
CCGCCTACACGATCTTTCAGAAGGTGATGCGGCACGACCCCGCCGATCCCGAGTGGACCGGCCGTGACCGCTTCGTCCTC
TCCCCCGGCCACACCTCGCTGACCCTCTACACCCAGCTCTTCCTCGCCGGGTACGAGGTGGAGCTGGACGACCTCAAGGC
CTTCCGCACGCACGGCTCCAGGACGCCGGGCCACCCCGAGTACGGGCACACGGCCGGCGTGGAGACCACCACGGGGCCGC
TGGGCCAGGGTGTGGCCAACGCGGTGGGCATGGCGATGGCGGCCCGCTACGAGCGCGGCCTGTTCGACCCCGAGGCCCCC
GAGGGCGAGTCGCCCTTCGACCACACCATCTGGGCGATCGTCAGCGACGGCGACCTCCAGGAGGGCGTCTCCGCGGAGGC
GTCGTCGCTCGCCGGTCACCAAAAGCTCGGCAATCTGGTCTTCCTCTACGACGACAACCACATCTCGATCGAGGGCGACA
CCGTGACCGCGTTCTCCGAGGACGTGCTGAAGCGCTACGAGGCGTACGGCTGGCACACACAGCGCGTCGAGCCCGCCGAG
AGCGGCGACGTGGACGTGCGCGCGCTGCACGCGGCGATGACGGCGGCGAAGGCCGAGACCGGCCGCCCCTCCATCATCGC
CATGCGCACGATCATCGCCTGGCCCGCCCCGAACGCCCAGAACACCGAGGCCTCCCACGGCTCCGCCCTCGGCGCGGACG
AGATCGCCGCCACCAAGCGCGTCCTCGGCTTCGACCCGGAGCGGTCCTTCGAGGTCGCCGACGAGGTCCTCGCCCACACC
CGCCGGGCCCTGGACCGGGGCGCCGAGGCGCACGCCGCCTGGGACAAGCGGATCGCCGCCTGGCGCGACGCCGCCCCCGA
GCGCGCGGCGCTGTTCGACCGCGTGGTCGCGGGCCGGCTGCCCGAGGGCTGGGAGAACGCCCTGCCGGTGTTCGAGACCG
GCAAGGCGGTCGCCACCCGGGCCGCGTCCGGCAAGGTCCTCCAGGCGCTCGGCCCGGTGCTGCCCGAACTGTGGGGCGGC
TCCGCAGACCTGGCCGGCTCGAACAACACGACGATCGACAAGACGTCGTCCTTCCTGCCCGGGGGCAACCCGCTCCCCGG
CGCCGACCCGTACGGCCGCACCGTGCACTTCGGCATCCGCGAGTTCTCCATGGCCGCGGAGATGAACGGCATCGCCCTGC
ACGGCAACACCCGGATCTACGGCGGCACCTTCCTGGTCTTCTCCGACTACATGCGCAACGCGGTGCGCATGTCCGCGCTG
ATGCAGCTGCCGGTGACGTACGTGTGGACGCACGACTCCATCGGCCTCGGTGAGGACGGGCCCACCCACCAGCCGGTCGA
ACACCTGGCCTCGCTGCGCGCGATCCCCGGCCTCAACGTCGTCCGCCCCGCCGACGCCAACGAGACCGCGACCGTGTGGG
CCGAGATCCTGCGCCGCCACTCCACCCACCCGGCGCCGCACGGCCTCGCCCTCACCCGCCAGGGCGTACCGACCTACGCG
CCGAACCCGGACGCGGCGCGCGGCGGGTACGTCCTCGCCGACGCGTCCACCGGCGCCCCGGACGTCGTCCTGATCGCCAC
CGGCTCCGAGGTGCAGCTCGCGATGGCCGCGCGGGAGACGCTGGAGGCCGAGGGCACCGCCACGCGCGTGGTGTCGATGC
CGTCCGTGGAGTGGTTCGAGGAGCAGCCCCGCGCCTACCGCGAGAGCGTGCTGCCGCCGTCCGTGCGGGCCCGGGTGGCC
GTGGAGGCCGGGATCGGCCTGACCTGGCACCGGTTCGTCGGGGACGCGGGCCGCATCGTCTCCCTGGAGCACTTCGGCGC
CTCCGCCGACGCGAAGACCCTGTTCAGCGAGTTCGGCTTCACCGCCGGGCACGTGGCCGCCGCCGCCCGGGACTCCCTGG
CCGCCGCCCGCGGCTGA

Protein sequence :
MSTQSSKQTVDGADRFEWTELDRRAVDTARILAADAVQKVGNGHPGTAMALAPAAYTIFQKVMRHDPADPEWTGRDRFVL
SPGHTSLTLYTQLFLAGYEVELDDLKAFRTHGSRTPGHPEYGHTAGVETTTGPLGQGVANAVGMAMAARYERGLFDPEAP
EGESPFDHTIWAIVSDGDLQEGVSAEASSLAGHQKLGNLVFLYDDNHISIEGDTVTAFSEDVLKRYEAYGWHTQRVEPAE
SGDVDVRALHAAMTAAKAETGRPSIIAMRTIIAWPAPNAQNTEASHGSALGADEIAATKRVLGFDPERSFEVADEVLAHT
RRALDRGAEAHAAWDKRIAAWRDAAPERAALFDRVVAGRLPEGWENALPVFETGKAVATRAASGKVLQALGPVLPELWGG
SADLAGSNNTTIDKTSSFLPGGNPLPGADPYGRTVHFGIREFSMAAEMNGIALHGNTRIYGGTFLVFSDYMRNAVRMSAL
MQLPVTYVWTHDSIGLGEDGPTHQPVEHLASLRAIPGLNVVRPADANETATVWAEILRRHSTHPAPHGLALTRQGVPTYA
PNPDAARGGYVLADASTGAPDVVLIATGSEVQLAMAARETLEAEGTATRVVSMPSVEWFEEQPRAYRESVLPPSVRARVA
VEAGIGLTWHRFVGDAGRIVSLEHFGASADAKTLFSEFGFTAGHVAAAARDSLAAARG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-120 46
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 9e-124 46