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Name : clpA (SCO6408) Accession : NP_630495.1 Strain : Streptomyces coelicolor A3(2) Genome accession: NC_003888 Putative virulence/resistance : Virulence Product : Clp protease ATP binding subunit Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 7073756 - 7076284 bp Length : 2529 bp Strand : - Note : SC3C8.27c, clpA, probable clp protease ATP binding subunit, len: 842 aa; highly similar to many e.g. CLPB_ECOLI clpB protein (857 aa), fasta scores; opt: 975 z-score: 1914.6 E(): 0, 46.8% identity in 857 aa overlap anCLAB_LYCES ATP-dependent clp protease DNA sequence : ATGACCAGCGGCTACATGGGCCCGGAGGGCGACCCGTTCGCGGAGTTCCTGGCACGCTTCTTCGGCGGGCCCAGGCCCCG GCAGATCGACATCGGCCGGCTGCTCAGCCAGCCCGCCCGGGAGCTGGTGCGCGGCGCCGCCCAGTACGCCGCCGAGCACG GCAGCCGGGACCTGGACACCGAGCACCTGCTGCGGGCCGCGCTCGCCACCGAGCCGACCCGGGGGCTGCTCAGCCGGGCC GGTGCCGACCCCGACTCGCTGGCCTCGCAGATCGACGAGCGGACCGGACCGGTGCAGCACCCGCCGGGCGAGGTCCCGCC GCCCACGTCGCTCTCGCTCACCCCGGCCGTCAAGCGTGCCCTGCTGGACGCGCACGAGCTGGCCCGCTCCACCGGCACCG GGTACATCGGCCCGGAGCACGTGCTCAGCGCCCTGGCCGCCAACCCCGACTCGGCCGCCGGGCACATCCTGAACGCGGCC CGCTTCGCGCCCTCGAACCTGCCCACGGAGACGCCGGAGGCCGCGAAGGGCCGTACCGAGAGCGCCCGGACCACGAACAC GCCGACCCTCGACAAGTACGGCCGCGATCTCACCGATCTGGCGCAGCAGGGCCGGATCGACCCGGTGATCGGGCGTGAGG AGGAGATCGAGCAGACCGTCGAGGTGCTCTCCCGGCGCGGCAAGAACAACCCCGTCCTGATCGGGGACGCCGGCGTCGGC AAGACCGCGATCGTGGAGGGGCTCGCCCAGCGCATCACCGACGGCGACGTGCCGGACGTGCTGATCGGGCGCCGGGTGGT CGCGCTCGACCTGACGGGCGTCGTCGCGGGCACCCGCTACCGGGGCGACTTCGAGGAGCGGATGAACAACATCGTGGGCG AGATCCGCGCCCACTCCGACGAGCTGATCATCTTCATCGACGAGCTGCACACCGTCGTCGGCGCGGGCGGGGGCGGCGAG AGCGGGTCGATGGACGCCGGGAACATCCTCAAGCCGGCCCTGGCCCGCGGCGAGCTGCACATCGTGGGCGCCACCACGCT GGAGGAGTACCGCAGGATCGAGAAGGACGCGGCCCTCGCCCGCCGCTTCCAGCCGATCCTGGTGCCGGAGCCCACCACCG CCGACGCGATCGAGATCCTGCGCGGCCTGCGCGACCGCTACGAGGCCCACCACCAGGTCCGCTACACCGACGAGGCGCTG GTCGCGGCCGTGGAGATGTCCGACCGCTACCTCACCGACCGGCGCCTGCCCGACAAGGCCATCGACCTGATCGACCAGGC GGGCGCCCGCGTGCGGCTGCGGGCGCGCACCAAGGGCACCGACGTACGGGCCCTGGAGCGCGAGGTCGACCAGCTGGTGA GGGACAAGGACCAGGCGGTCGCGGACGAGCAGTACGAGCAGGCGACCCAGCTGCGGGACCGGATCGTCGGGCTGAAGCAG CGCATCACCGAGGCCACCGGCGACGGCCAGGCCGACGAGGGCCTCGACCTGGTCGTGGACACCGAGTCCATCGCCGAGGT GGTCTCCCGGCAGACCGGCATCCCGGTCAGCAGCCTCACCCAGGAGGAGAAGGACCGCCTGCTGGGCCTGGAGTCCCACC TGCACGAGCGGGTCGTCGGCCAGGACGAGGCGGTACGGGTCGTCTCCGACGCCGTGCTGCGCTCCCGCGCCGGGCTGTCC AGTGCGGACCGGCCCATCGGCAGCTTCCTCTTCCTCGGCCCGACCGGCGTCGGCAAGACCGAGCTGGCCCGGGCACTGGC CGAGGCGCTGTTCGGCAGCGAGGACCGGATGGTGCGCCTCGACATGAGCGAGTACCAGGAGCGCCACACCGTCAGCCGCC TGGTCGGCGCCCCGCCCGGCTACGTCGGGCACGAGGAGGCCGGTCAGCTCACCGAGGTGGTGCGCCGGCACCCGTACTCG CTGCTCCTGCTGGACGAGGTGGAGAAGGCGCACCCCGACGTCTTCAACATCCTGCTCCAGGTCCTGGACGACGGGCGGCT GACCGACTCGCAGGGCCGGACGGTGGACTTCTCCAACACGGTCGTCGTGATGACCAGCAACCTGGGCTCCGACGTGATCA CCCGGCGCGGTGCCGGCATCGGCTTCGGCGCGGGCGGCGCGGAGGCGGACGAGGAAGCCCGGCGCGAGCAGGTGCTGCGC CCGCTGCGGGAGCACTTCCGGCCCGAGTTCCTCAACCGCGTCGACGAGATCGTGGTCTTCCGCCAGCTCAGCGGCGAGCA GCTGCGGCAGATCACCAGCCTGCTCCTGGAGCAGACCCGTCGCATGGTGCACGCGCAGGGCGTCACCGTCGACTTCACCG ACGCGGCCGTGGACTGGCTCGCCGAGCGCGGCTACCAGCCCGAGTACGGCGCCCGACCGCTGCGCCGCACCATCCAGCGC GAGGTGGACAACGAGCTGTCCCGGCTGCTGCTCGACGGCCGGGTGGCGGAGGGCGGCCGGGTGACGGTCGACGTCGAGGA CGGGCGGCTGGCGTTCCGCACGCCGGAGCGACCCGTCCCCGAACTGTGA Protein sequence : MTSGYMGPEGDPFAEFLARFFGGPRPRQIDIGRLLSQPARELVRGAAQYAAEHGSRDLDTEHLLRAALATEPTRGLLSRA GADPDSLASQIDERTGPVQHPPGEVPPPTSLSLTPAVKRALLDAHELARSTGTGYIGPEHVLSALAANPDSAAGHILNAA RFAPSNLPTETPEAAKGRTESARTTNTPTLDKYGRDLTDLAQQGRIDPVIGREEEIEQTVEVLSRRGKNNPVLIGDAGVG KTAIVEGLAQRITDGDVPDVLIGRRVVALDLTGVVAGTRYRGDFEERMNNIVGEIRAHSDELIIFIDELHTVVGAGGGGE SGSMDAGNILKPALARGELHIVGATTLEEYRRIEKDAALARRFQPILVPEPTTADAIEILRGLRDRYEAHHQVRYTDEAL VAAVEMSDRYLTDRRLPDKAIDLIDQAGARVRLRARTKGTDVRALEREVDQLVRDKDQAVADEQYEQATQLRDRIVGLKQ RITEATGDGQADEGLDLVVDTESIAEVVSRQTGIPVSSLTQEEKDRLLGLESHLHERVVGQDEAVRVVSDAVLRSRAGLS SADRPIGSFLFLGPTGVGKTELARALAEALFGSEDRMVRLDMSEYQERHTVSRLVGAPPGYVGHEEAGQLTEVVRRHPYS LLLLDEVEKAHPDVFNILLQVLDDGRLTDSQGRTVDFSNTVVVMTSNLGSDVITRRGAGIGFGAGGAEADEEARREQVLR PLREHFRPEFLNRVDEIVVFRQLSGEQLRQITSLLLEQTRRMVHAQGVTVDFTDAAVDWLAERGYQPEYGARPLRRTIQR EVDNELSRLLLDGRVAEGGRVTVDVEDGRLAFRTPERPVPEL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 3e-159 | 51 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpA | NP_630495.1 | Clp protease ATP binding subunit | VFG0079 | Protein | 3e-180 | 53 |
| clpA | NP_630495.1 | Clp protease ATP binding subunit | VFG0080 | Protein | 9e-153 | 50 |
