Gene Information

Name : SC2H4.04c (SCO6222)
Accession : NP_630323.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Unknown
Product : aminotransferase AlaT
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 6843172 - 6844380 bp
Length : 1209 bp
Strand : -
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGGAGTTCCGGCAGTCGAACAAGCTCAGCGAGGTCTGTTACGAGATCCGCGGCCCGGTCATCGAGCACGCCAACGCGCT
GGAGGAGGCGGGGCACAGCGTGCTGCGCCTGAACACCGGCAACCCCGCCCTCTTCGGGTTCGAGGCGCCCGAGGAGATCG
TCCAGGACATGATCCGCATGCTGCCGAGGGCGCACGGCTACACGGACTCGCGCGGCATCCTCTCCGCCCGCCGGGCCGTC
GCCCAGCGCTACCAGGCGCTCGGCCTGGAGGTGGACGTGGACGACGTCTTCCTGGGCAACGGCGTCTCGGAGCTGATCTC
CATGGCCGTGCAGGCCCTCCTTGAGGACGGCGACGAGGTGCTGATCCCCGCCCCCGACTTCCCCCTCTGGACGGCGGTGA
CCACCCTCGCGGGCGGCAAGGCGGTGCACTACCTCTGCGACGAGCAGGCCGAGTGGTACCCCGACCTGGCCGACATGGAG
GCGAAGATCACCGACCGCACCAAGGCGGTCGTCATCATCAACCCCAACAACCCCACCGGCGCCGTCTACCCCAAGGAGAT
CGTCGAGGGCATCCTCGACCTCGCCCGCCGGCACGGCCTGATGGTCCTCGCCGACGAGATCTACGACCAGATCCTGTACG
ACGACGCCGTGCACCACTCGGCCGCGTCCCTCGCCCCCGACCTGGTGGTGCTGACCTTCTGCGGCCTGTCCAAGACGTAC
CGGGTGGCGGGTTTCCGCTCCGGCTGGCTGGTGGTGACGGGGCCGAAGCAGCACGCGAGGGACTACCTGGAGGGCCTGAC
CATGCTGGCCTCCATGCGCCTGTGCGCCAACGCGCCCGCCCAGTACGCCATCCAGGCCGCGCTCGGCGGCCGCCAGTCCA
TCCGCGAGCTGACGGCCCCCGGCGGACGGCTGCACGAGCAGCGGGACGTCGCCTGGGAGAAGCTCAACGAGATCCCCGGC
ATCTCCTGCGTCAAGCCCAAGGGCGCGCTGTACGCCTTCCCGCGCATCGACCCGGCCGTCCACAAGATCCACGACGACGA
GCGCTTCGTCCTGGACCTGCTGCTGCGGGAGAAGATCCAGGTGGTGCAGGGGACGGGCTTCAACTGGCCCTCCCCCGACC
ACTTCCGCATCCTGACCCTGCCGCACGCGGAGGACCTGGAGGCCGCGATCGGACGCATCGGGCGCTTCCTGAGCGGGTAC
CGGCAGTAG

Protein sequence :
MEFRQSNKLSEVCYEIRGPVIEHANALEEAGHSVLRLNTGNPALFGFEAPEEIVQDMIRMLPRAHGYTDSRGILSARRAV
AQRYQALGLEVDVDDVFLGNGVSELISMAVQALLEDGDEVLIPAPDFPLWTAVTTLAGGKAVHYLCDEQAEWYPDLADME
AKITDRTKAVVIINPNNPTGAVYPKEIVEGILDLARRHGLMVLADEIYDQILYDDAVHHSAASLAPDLVVLTFCGLSKTY
RVAGFRSGWLVVTGPKQHARDYLEGLTMLASMRLCANAPAQYAIQAALGGRQSIRELTAPGGRLHEQRDVAWEKLNEIPG
ISCVKPKGALYAFPRIDPAVHKIHDDERFVLDLLLREKIQVVQGTGFNWPSPDHFRILTLPHAEDLEAAIGRIGRFLSGY
RQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-125 63
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-125 63
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-125 63
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 2e-125 63