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Name : pyk2; SC8F4.27c (SCO5423) Accession : NP_629562.1 Strain : Streptomyces coelicolor A3(2) Genome accession: NC_003888 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : - Position : 5892975 - 5894405 bp Length : 1431 bp Strand : - Note : SC8F4.27c, pyk2, pyruvate kinase, len: 476 aa; strongly similar to many e.g. SW:Q46078 (KPYK_CORGL) pyruvate kinase from Corynebacterium glutamicum (Brevibacterium flavum) (475 aa) fasta scores; opt: 1693, z-score: 1907.7, E(): 0, 55.3% identity in 474 aa DNA sequence : ATGCGCCGTTCGAAAATCGTCTGTACTCTCGGCCCCGCGGTCGACTCCCACGAGCAGCTCGTCACGCTGATCGAAGCCGG CATGAACGTGGCCCGCTTCAACTTCAGCCATGGCACCCACGCCGAGCACCAGGGTCGTTACGACCGGGTCCGGGCCGCCG CCAAGGAGACCGGCCGGGCCATCGGCGTCCTCGCCGACCTCCAGGGCCCGAAGATCCGCCTGGAGACCTTCGCGGAGGGC CCCGTCGAGCTGGTGCGCGGTGACGAGTTCACCATCACCGCCGAGGACGTCCCGGGCGACAGGACGATCTGCGGCACGAC CTACAAGGGCCTGCCCGGTGACGTCACCAAGGGCGACCAGGTGCTCATCAACGACGGCAACGTCGAGCTGAAGGTCACCG AGGTCGAGGGCCCCCGGGTGAAGACGATCGTCATCGAGGGCGGCGTCATCTCCGACCACAAGGGCATCAACCTGCCGGGC GCGGCGGTCAACGTCCCCGCGCTGAGCGAGAAGGACGTCGAGGACCTCCGGTTCGCGCTGCGCATGGGCTGCGACCTGGT CGCCCTCTCCTTCGTCCGGGACGCCAAGGACGTCGCCGACGTGCACCGCGTCATGGACGAGGAGGGCCGCCGGGTCCCGG TGATCGCCAAGGTCGAGAAGCCCCAGGCGGTCGACAACATGGAGGACGTCGTGATGGCGTTCGACGGCGTGATGGTCGCC CGTGGCGACCTGGCCGTCGAGTACCCGCTCGAGAAGGTCCCCATGGTGCAGAAGCGCCTGATCGAGCTGTGCCGGCGCAA CGCCAAGCCGGTGATCGTGGCGACCCAGATGATGGAGTCGATGATCACGAACTCCCGGCCGACCCGCGCCGAGGCCTCCG ACGTGGCCAACGCGATCCTGGACGGCGCCGACGCGGTCATGCTGTCCGCCGAGTCGAGCGTGGGCGCCTACCCGATCGAG ACCGTCAAGACGATGTCGAAGATCGTCACCGCCGCCGAGCAGGAGCTGCTCTCCAAGGGCCTCCAGCCGCTGGTGCCGGG CAAGAAGCCGCGCACGCAGGGCGGTTCGGTGGCCCGTGCGGCCGCCGAGATCGCCGACTTCCTGGGCGGCAAGGGCCTGG TCGCCTTCACCCAGTCCGGCGACACCGCCCGCCGGCTCTCCCGCTATCGCGCGGCCCAGCCGATCCTCGCCTTCACCACC GACGAGTCCACCCGCAACCAGCTGGCGCTCAGCTGGGGAGTGGAGCCGCACGTGGTGCCGTTCGTGAACACCACGGACGA GATGGTGGACCTGGTGGACCAGGAGACGGCCCGCCTCGGCCGGTTCAGCGACGGCGACACCGTCGTGATCACCGCCGGTT CGCCCCCCGGCGTGTCCGGCACCACCAACATGGTGCGGGTCCTCCACCTGGGCGAGACACGGCGCGGCTGA Protein sequence : MRRSKIVCTLGPAVDSHEQLVTLIEAGMNVARFNFSHGTHAEHQGRYDRVRAAAKETGRAIGVLADLQGPKIRLETFAEG PVELVRGDEFTITAEDVPGDRTICGTTYKGLPGDVTKGDQVLINDGNVELKVTEVEGPRVKTIVIEGGVISDHKGINLPG AAVNVPALSEKDVEDLRFALRMGCDLVALSFVRDAKDVADVHRVMDEEGRRVPVIAKVEKPQAVDNMEDVVMAFDGVMVA RGDLAVEYPLEKVPMVQKRLIELCRRNAKPVIVATQMMESMITNSRPTRAEASDVANAILDGADAVMLSAESSVGAYPIE TVKTMSKIVTAAEQELLSKGLQPLVPGKKPRTQGGSVARAAAEIADFLGGKGLVAFTQSGDTARRLSRYRAAQPILAFTT DESTRNQLALSWGVEPHVVPFVNTTDEMVDLVDQETARLGRFSDGDTVVITAGSPPGVSGTTNMVRVLHLGETRRG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 2e-80 | 43 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-80 | 43 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-80 | 43 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 4e-80 | 43 |
| pykA | NP_273151.1 | pyruvate kinase | Not tested | IHT-A | Protein | 4e-68 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pyk2; SC8F4.27c | NP_629562.1 | pyruvate kinase | VFG0479 | Protein | 5e-81 | 43 |
