Gene Information

Name : SCBAC5H2.23; thrA (SCO5354)
Accession : NP_629494.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Unknown
Product : homoserine dehydrogenase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0460
EC number : 1.1.1.3
Position : 5822215 - 5823504 bp
Length : 1290 bp
Strand : +
Note : catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine

DNA sequence :
ATGCGTACGCGTCCGCTGAAGGTGGCGCTGCTGGGCTGTGGAGTGGTCGGCTCAAAGGTGGCGCGCATCATGACGACGCA
CGCCGCCGACCTCGCCGCCCGGATCGGGGCCCCGGTGGAGCTCGCGGGCGTCGCCGTACGGCGGCCCGACAAGGTGCGGG
AGGGGATCGACCCGGCCCTCGTCACCACCGACGCCACCGCGCTCGTCAAGCGCGGGGACATCGACGTCGTCGTCGAGGTC
ATCGGGGGGATCGAGCCCGCGCGGACGCTCATCACCACCGCCTTCGCGCACGGCGCCTCCGTGGTCTCCGCCAACAAGGC
GCTCATCGCCCAGGACGGCGCCGCCCTGCACGCCGCCGCCGACGAGCACGGCAAGGACCTGTACTACGAGGCCGCCGTCG
CCGGTGCCATCCCGCTGATCCGGCCGCTGCGCGAGTCCCTCGCCGGCGACAAGGTCAACCGGGTGCTCGGCATCGTCAAC
GGGACCACCAACTTCATCCTCGACGCCATGGACTCGACCGGGGCCGGCTATCAGGAAGCGCTCGACGAGGCCACGGCCCT
CGGGTACGCCGAGGCCGACCCGACCGCCGACGTCGAGGGCTTCGACGCCGCAGCCAAGGCCGCCATCCTCGCCGGGATCG
CCTTCCACACGCGCGTACGCCTCGACGACGTCTACCGCGAGGGCATGACCGAGGTCACCGCCGCCGACTTCGCCTCCGCC
AAGGAGATGGGCTGCACCATCAAGCTGCTCGCCATCTGCGAGCGGGCGGCGGACGGAGGGTCGGTCACCGCACGCGTGCA
TCCCGCGATGATCCCGCTCAGCCATCCGCTGGCCAACGTGCGCGAGGCGTACAACGCCGTGTTCGTGGAGTCCGACGCCG
CCGGTCAGCTCATGTTCTACGGGCCCGGCGCCGGCGGTTCGCCGACCGCGTCCGCCGTGCTCGGCGACCTGGTGGCCGTG
TGCCGCAACCGGCTGGGCGGAGCGACCGGACCCGGTGAGTCCGCGTACGCCGCCCTGCCCGTCTCCCCGATGGGCGACGT
CGTCACGCGCTACCACATCAGCCTCGACGTGGCCGACAAACCGGGCGTGCTCGCCCAGGTCGCGACCGTGTTCGCGGAGC
ACGGTGTCTCCATCGACACCGTGCGGCAGTCCGGCAAGGACGGCGAGGCATCCCTCGTCGTCGTCACCCATCGCGCGTCC
GACGCCGCCCTCGGCGGTACGGTCGAGGCGCTGCGCAAGCTCGACACCGTGCGGGGTGTCGCCAGCATCATGCGGGTTGA
AGGAGAGTAA

Protein sequence :
MRTRPLKVALLGCGVVGSKVARIMTTHAADLAARIGAPVELAGVAVRRPDKVREGIDPALVTTDATALVKRGDIDVVVEV
IGGIEPARTLITTAFAHGASVVSANKALIAQDGAALHAAADEHGKDLYYEAAVAGAIPLIRPLRESLAGDKVNRVLGIVN
GTTNFILDAMDSTGAGYQEALDEATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLDDVYREGMTEVTAADFASA
KEMGCTIKLLAICERAADGGSVTARVHPAMIPLSHPLANVREAYNAVFVESDAAGQLMFYGPGAGGSPTASAVLGDLVAV
CRNRLGGATGPGESAYAALPVSPMGDVVTRYHISLDVADKPGVLAQVATVFAEHGVSIDTVRQSGKDGEASLVVVTHRAS
DAALGGTVEALRKLDTVRGVASIMRVEGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00305 YP_008207770.1 Homoserine dehydrogenase Not tested AbaR25 Protein 6e-48 41
BJAB0868_00309 YP_008211635.1 Homoserine dehydrogenase Not tested AbaR26 Protein 6e-48 41