Gene Information

Name : 2SCK36.07c (SCO4984)
Accession : NP_629136.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Unknown
Product : aminotransferase AlaT
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 5421700 - 5422911 bp
Length : 1212 bp
Strand : -
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGCAGGTGATCCAGTCGACCAAGCTCGCCAACGTCTGTTACGAGATCCGGGGCCCGGTGCTCGAGGAGGCGATGCGGCT
GGAGGCGGCCGGGCACCGCATCCTGAAGCTGAACACCGGCAATCCGGCAGCCTTCGGCTTCGAGTGCCCGCCGGAGATTT
TGGAGGACATCCTCCGCAACGTCTCCACGGCGCACGGCTACGGCGACGCGAAGGGCCTGCTGGCGGCGCGCCGGGCGGTC
GTCATGCACAACCAGACCCTCGGCATCGAGACGGACGTCGAGCACGTCTTCATCGGCAACGGCGTCTCCGAGCTGATCGT
GATGGCGATGCAGGGCCTGCTCGACGACGGCGACGAGGTCCTCGTCCCGGCCCCCGACTACCCGCTGTGGACGGCCGCCG
TCTCACTGTCCGGCGGTACGGCGGTGCACTACCGCTGCGACGAGCAGTCCGACTGGATGCCCGACCTCGCGGACGTGGAG
CGGAAGATCACCGACCGCACCAAGGCCCTGGTGATCATCAATCCGAACAACCCGACGGGCGCGGTCTACGACGACGCGAT
GCTGCGCGGACTGACGGACATCGCCCGCCGGCACAACCTGCTGGTCTGCTCGGACGAGATCTACGACAAGATCCTCTACG
ACGACGCCACCCACACCCCGACCGCCGCGATCGCCCCCGACCTGCTCACCCTCACCTTCAACGGCATGTCGAAGGCGTAC
CGGGTGGCCGGTTACCGGGTCGGCTGGATGTCGATCTCCGGGCCGCGCGCGCACGCCGAGTCCTACATCGAGGGCCTGAC
GATCCTGGCGAACATGCGCCTGTGCGCCAACATGCCGGGCCAGCACGGCGTGGTCGCGGCGCTCAGCGGGCGGCAGACCA
TCAACGAGCTGGTGCTGCCGGGCGGGCGGCTGCGCGAGCAGCGCGACGCCGCCCACGAGGCACTGACCAGCATTCCCGGC
GTGACCTGCGTGAAGCCGAAGGGTGCGCTGTACCTCTTCCCGCGGCTCGACCCCAAGGTCTTCAAGATCAAGGACGACCG
GCGGATGGTCCTGGACCTGCTGCGCCAGGAGAAGATCATGGTCGTCCAGGGCACCGGCTTCAACTGGCCCGAGCCCGACC
ACTTCCGGGTGGTGACCCTGCCGACGGCCGCGGACCTGCGCGAGGCGGTGGACCGGATCGGGAACTTCCTGGACGGGTAC
AGCCAGCCCTGA

Protein sequence :
MQVIQSTKLANVCYEIRGPVLEEAMRLEAAGHRILKLNTGNPAAFGFECPPEILEDILRNVSTAHGYGDAKGLLAARRAV
VMHNQTLGIETDVEHVFIGNGVSELIVMAMQGLLDDGDEVLVPAPDYPLWTAAVSLSGGTAVHYRCDEQSDWMPDLADVE
RKITDRTKALVIINPNNPTGAVYDDAMLRGLTDIARRHNLLVCSDEIYDKILYDDATHTPTAAIAPDLLTLTFNGMSKAY
RVAGYRVGWMSISGPRAHAESYIEGLTILANMRLCANMPGQHGVVAALSGRQTINELVLPGGRLREQRDAAHEALTSIPG
VTCVKPKGALYLFPRLDPKVFKIKDDRRMVLDLLRQEKIMVVQGTGFNWPEPDHFRVVTLPTAADLREAVDRIGNFLDGY
SQP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-122 61
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-122 61
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 2e-122 61
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-122 61