Gene Information

Name : SCK13.05c (SCO4913)
Accession : NP_629066.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 5345752 - 5347194 bp
Length : 1443 bp
Strand : -
Note : SCK13.05c, probable aldehyde dehydrogenase, len: aa; similar to SW:DHA5_YEAST (EMBL:X85987) Saccharomyces cerevisiae aldehyde dehydrogenase 2 (EC 1.2.1.5) Ald5, 506 aa; fasta scores: opt: 1336 z-score: 1519.8 E(): 0; 46.1% identity in 462 aa overlap. Cont

DNA sequence : 
ATGGCATCCGCACCCGCATTCGACTACGCACCGGCACCCGAGTCCCGCGCGGTCGTCGACATCGCCCCCTCCTACGGCGT
GTTCATCGACGGCGAGTTCACCGAGGCGGCCGACGGCAAGGTCTTCAAGACGGTCTCCCCCGCCACCGAGGAGGTCCTCT
CCGAGGTCGCCGAGGCCGGCGAGGCGGACGTCGACCGCGCCGTGAAGGCCGCCCGCAAGGCCTTCGAGAAGTGGTCGGCG
CTGCCCGGCGCGGAGCGTGCGAAGTACCTCTTCCGCATCGCCCGCATCATCCAGGAACGCAGCCGGGAACTGGCCGTCCT
GGAAACCCTCGACAACGGCAAGCCGATCAGGGAGACCCGCGACGCGGACCTCCCCCTGGTCGCCGCGCACTTCTTCTACT
ACGCGGGCTGGGCCGACAAGCTGGACCACGCCGGCTACGGCGCCGACCCCCGCCCCCTGGGCGTGGCGGGCCAGGTCATC
CCCTGGAACTTCCCGCTCCTGATGCTGGCGTGGAAGATCGCCCCGGCCCTGGCCACCGGCAACACGGTGGTCCTGAAGCC
CGCCGAGACGACCCCCCTCTCCGCCCTGTTCTTCGCGGACATCTGCCGCCAGGCCGGGCTGCCCAAGGGCGTCGTCAACA
TCATCACCGGCGACGGCCGCGCCGGGGCGGCACTCACCGCCCACCCCGACGTGAACAAGGTCGCCTTTACGGGCTCCACG
GCGGTCGGCAAGCAGATCGCGCGCACGGTCGCGGGCACCCGCAAGAAGCTCACCCTCGAACTGGGCGGCAAGGGCGCCAA
CATCGTCTTCGACGACGCCCCGATCGACCAGGCCGTAGAGGGCATCGTCAACGGCATCTTCTTCAACCAGGGCCAGGTCT
GCTGCGCGGGCAGCCGCCTCCTGGTCCAGGAGTCGATCCACGACGAGCTGCTGGACTCCCTGAAGCGCAGGCTCACCACC
CTCCGCCTGGGCGACCCGCTGGACAAGAACACGGACATCGGCGCGATCAACTCCGCCGAGCAGCTGGCCCGTATCACCGC
CCTCGCCGACCAGGGCGAGGCGGAGGGCGCCGAGCGCTGGTCCCCGGCCTGCGAACTGCCCTCCGCCGGCTACTGGTTCG
CCCCGACGCTCTTCACGAACGTCACCCAGGCGCACACGGTCGCCCGCGACGAGATCTTCGGCCCGGTCCTGTCCGTCCTC
ACCTTCCGCACGCCGGACGAGGCGGTCGCCAAGGCCAACAACACGCCGTACGGCCTGTCGGCGGGCATCTGGACGGAGAA
GGGCTCGCGCATCCTGGCGGTCGCGAACAAGCTCCGTGCCGGTGTGATCTGGTCCAACACGTTCAACAAGTTCGACCCGA
CGTCGCCGTTCGGCGGCTACAAGGAGTCGGGCTTCGGCCGCGAGGGCGGCCGCCACGGCCTGGAGGCGTACCTCGATGTC
TGA

Protein sequence : 
MASAPAFDYAPAPESRAVVDIAPSYGVFIDGEFTEAADGKVFKTVSPATEEVLSEVAEAGEADVDRAVKAARKAFEKWSA
LPGAERAKYLFRIARIIQERSRELAVLETLDNGKPIRETRDADLPLVAAHFFYYAGWADKLDHAGYGADPRPLGVAGQVI
PWNFPLLMLAWKIAPALATGNTVVLKPAETTPLSALFFADICRQAGLPKGVVNIITGDGRAGAALTAHPDVNKVAFTGST
AVGKQIARTVAGTRKKLTLELGGKGANIVFDDAPIDQAVEGIVNGIFFNQGQVCCAGSRLLVQESIHDELLDSLKRRLTT
LRLGDPLDKNTDIGAINSAEQLARITALADQGEAEGAERWSPACELPSAGYWFAPTLFTNVTQAHTVARDEIFGPVLSVL
TFRTPDEAVAKANNTPYGLSAGIWTEKGSRILAVANKLRAGVIWSNTFNKFDPTSPFGGYKESGFGREGGRHGLEAYLDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aldA ACK75580.1 aldehyde dehydrogenase Not tested VPI Protein 3e-55 44
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 4e-55 44
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-73 44
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 6e-56 43
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 6e-56 43
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 6e-56 43
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 2e-55 43
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 2e-55 43
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 3e-56 43
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 3e-56 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-75 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-78 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-78 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-78 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-77 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SCK13.05c NP_629066.1 aldehyde dehydrogenase VFG0082 Protein 1e-75 42