Gene Information

Name : SCK20.12 (SCO4871)
Accession : NP_629025.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Resistance
Product : TetR family transcriptional regulator
Function : -
COG functional category : K : Transcription
COG ID : COG1309
EC number : -
Position : 5300705 - 5301355 bp
Length : 651 bp
Strand : +
Note : SCK20.12, probable tetR-family transcriptional regulator, len: 216 aa; similar to SW:TER1_ECOLI (EMBL:X61367) Escherichia coli tetracycline repressor protein class A TetR, 216 aa; fasta scores: opt: 437 z-score: 544.2 E(): 8.9e-23; 43.2% identity in 199 a

DNA sequence : 
GTGAGTACGGAACGACGCGCCCCCCTCGACCGCCGACGGGTCGCGGACACGGCGCTGAAACTGCTGAACGAGGTCGGCCT
CGACGGCCTGACCCTGCGCGCCATCGCCAGGGAGCTGGACGTGAAGGCGCCCGCCCTGTACTGGCACTTCAAGGACAAGC
AGGCCTTGCTCGACGAGATGGCCACCGAGATGTACCGGCGCATGATCGCCGGGACCCCCCTGGATCCGGCCGACACCTGG
CGGGAACGGCTGCTCACGGCCAACCGCGGCCTGCGCGCCGCCCTGCTCGCCTACCGCGACGGTGCCAAGGTGTTCAGCGG
TTCACGTTTCACCGGCGCGGTGCACGCCGAGTACATGGAGGGAACCCTGCGGCTGTTCACCGCCGCCGGGCTCACCCTCG
CGCAGGCGGTTAGGGCGACCACGACGACGTACCTGTTCACGCTCGGCTTCGTCACCGAGGAACAGGGCGTCGAGCCCCTG
CCCGGCGAGCGCCGGGAGGGCTTCGACGTGGAGGAACGCGCCCGCCTGCTGGCCGACTACCCCCTGACGGCCGCGGCGGG
CGCGGAGATCTTCACGGACTACGACCGGCACTTCGAGGAGTCGCTGGCCCTGGTGATCGAGGGTGTCGCGGCGACCTACG
GCCTCGACTGA

Protein sequence : 
MSTERRAPLDRRRVADTALKLLNEVGLDGLTLRAIARELDVKAPALYWHFKDKQALLDEMATEMYRRMIAGTPLDPADTW
RERLLTANRGLRAALLAYRDGAKVFSGSRFTGAVHAEYMEGTLRLFTAAGLTLAQAVRATTTTYLFTLGFVTEEQGVEPL
PGERREGFDVEERARLLADYPLTAAAGAEIFTDYDRHFEESLALVIEGVAATYGLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetR1 YP_005176239.1 tetracycline repressor protein Not tested ICEPmu1 Protein 2e-22 43
tetR2 YP_005176247.1 tetracycline repressor protein Not tested ICEPmu1 Protein 2e-22 43