Gene Information

Name : 4CL-2; SCD10.15 (SCO4383)
Accession : NP_628552.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Unknown
Product : 4-coumarate:CoA ligase
Function : -
COG functional category : I : Lipid transport and metabolism
COG ID : COG0318
EC number : -
Position : 4799896 - 4801464 bp
Length : 1569 bp
Strand : +
Note : SCD10.15, 4CL-2, 4-coumarate:CoA ligase, len: 522 aa; similar to many eukaryotic ones, e.g. TR:O81139 (EMBL:AF041049) Populus tremuloides 4-coumarate:CoA ligase (EC 6.2.1.12) 4CL2, 535 aa; fasta scores: opt: 1412 z-score: 1497.3 E(): 0; 44.2% identity in

DNA sequence :
GTGTTCCGCAGCGAGTACGCAGACGTCCCGCCCGTCGACCTGCCCATCCACGACGCCGTGCTCGGCGGGGCCGCCGCCTT
CGGGAGCACCCCGGCGCTGATCGACGGCACCGACGGCACCACCCTCACCTACGAGCAGGTGGACCGGTTCCACCGGCGCG
TCGCCGCCGCCCTCGCCGAGACCGGCGTGCGCAAGGGCGACGTCCTCGCCCTGCACAGCCCCAACACCGTCGCCTTCCCC
CTGGCCTTCTACGCCGCCACCCGCGCGGGCGCCTCCGTCACCACGGTGCATCCGCTCGCGACGGCGGAGGAGTTCGCCAA
GCAGCTGAAGGACAGCGCGGCCCGCTGGATCGTCACCGTCTCACCGCTCCTGTCCACCGCCCGCCGGGCCGCCGAACTCG
CGGGCGGCGTCCAGGAGATCCTGGTCTGCGACAGCGCGCCCGGTCACCGCTCCCTCGTCGACATGCTGGCCTCGACCGCG
CCCGAACCGTCCGTCGCCATCGACCCGGCCGAGGACGTCGCCGCCCTGCCGTACTCCTCGGGCACCACCGGCACCCCCAA
GGGCGTCATGCTCACACACCGGCAGATCGCCACCAACCTCGCCCAGCTCGAACCGTCGATGCCGTCCGCGCCCGGCGACC
GCGTCCTCGCCGTGCTGCCGTTCTTCCACATCTACGGCCTGACCGCCCTGATGAACGCCCCGCTCCGGCTCGGCGCCACC
GTCGTGGTCCTGCCCCGCTTCGACCTGGAGCAGTTCCTCGCCGCCATCCAGAACCACCGCATCACCAGCCTGTACGTCGC
CCCGCCGATCGTCCTGGCCCTCGCCAAACACCCCCTGGTCGCCGACTACGACCTCTCCTCGCTGAGGTACATCGTCAGCG
CCGCCGCCCCGCTCGACGCGCGTCTCGCCGCCGCCTGCTCGCAGCGGCTCGGCCTGCCGCCCGTCGGCCAGGCCTACGGC
ATGACCGAACTGTCCCCGGGCACCCACGTCGTCCCCCTGGACGCGATGGCCGACGCGCCGCCCGGCACCGTCGGCAGGCT
CATCGCGGGCACCGAGATGCGCATCGTCTCCCTCACCGACCCGGGCACGGACCTCCCCGCCGGAGAGTCCGGGGAGATCC
TCATCCGCGGCCCCCAGATCATGAAGGGCTACCTGGGCCGCCCCGACGCCACCGCCGCCATGATCGACGAGGAGGGCTGG
CTGCACACCGGGGACGTCGGACACGTCGACGCCGACGGCTGGCTGTTCGTCGTCGACCGCGTCAAGGAACTGATCAAGTA
CAAGGGCTTCCAGGTGGCCCCCGCCGAACTGGAGGCCCACCTGCTCACCCACCCCGGCGTCGCCGACGCGGCCGTCGTCG
GCGCCTACGACGACGACGGCAACGAGGTACCGCACGCCTTCGTCGTCCGCCAGCCGGCCGCACCCGGCCTCGCGGAGAGC
GAGATCATGATGTACGTCGCCGAACGCGTCGCCCCCTACAAACGCGTCCGCCGGGTCACCTTCGTCGACGCCGTCCCCCG
CGCCGCCTCCGGCAAGATCCTCCGCCGACAGCTCAGGGAGCCGCGATGA

Protein sequence :
MFRSEYADVPPVDLPIHDAVLGGAAAFGSTPALIDGTDGTTLTYEQVDRFHRRVAAALAETGVRKGDVLALHSPNTVAFP
LAFYAATRAGASVTTVHPLATAEEFAKQLKDSAARWIVTVSPLLSTARRAAELAGGVQEILVCDSAPGHRSLVDMLASTA
PEPSVAIDPAEDVAALPYSSGTTGTPKGVMLTHRQIATNLAQLEPSMPSAPGDRVLAVLPFFHIYGLTALMNAPLRLGAT
VVVLPRFDLEQFLAAIQNHRITSLYVAPPIVLALAKHPLVADYDLSSLRYIVSAAAPLDARLAAACSQRLGLPPVGQAYG
MTELSPGTHVVPLDAMADAPPGTVGRLIAGTEMRIVSLTDPGTDLPAGESGEILIRGPQIMKGYLGRPDATAAMIDEEGW
LHTGDVGHVDADGWLFVVDRVKELIKYKGFQVAPAELEAHLLTHPGVADAAVVGAYDDDGNEVPHAFVVRQPAAPGLAES
EIMMYVAERVAPYKRVRRVTFVDAVPRAASGKILRRQLREPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1475 YP_001800869.1 acyl-CoA synthetase Not tested Not named Protein 1e-85 48