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Name : SCD78.28c; serS (SCO3961) Accession : NP_628145.1 Strain : Streptomyces coelicolor A3(2) Genome accession: NC_003888 Putative virulence/resistance : Unknown Product : seryl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0172 EC number : 6.1.1.11 Position : 4360548 - 4361825 bp Length : 1278 bp Strand : - Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : GTGATTGACCTTCGCCTGCTCCGTGAGGACCCCGACCGTGTGCGCGCCTCGCAGCGCGCCCGTGGAGAGGACGTCGCGCT CGTCGACTCCCTCCTGTCCGCCGACGAACGGCGCAGGTCGTCCGGCGTCCGCTTCGACGAGCTGCGCGCCGAGCAGAAGG GCCTCGGCAAGCTGATCGGCAAGGCCGCCGGAGACGAGAAGGCCGAGCTGCTCAAGCGGGCCGAGCAGCTCAAGACCGAC GTCAAGGCCGCCGACGCCGAGCGCGACGCGGCCGACGCCGAGACCCAGGAGCTGCTCCAGCGGCTCGGCAACCTCGTCCA CCCCGACGTGCCCGTCGGCGGCGAGGAGGACTTCGTCACGCTGGAGACGCACGGCACGCACCGCGACTTCGCCGCCGAGG GCTTCGAGCCCAGGGACCACCTGGAGCTGGGCCAGCTGCTCGGCGCCATCGACGTGGAGCGCGGCGCGAAGGTCTCCGGC TCGCGCTTCTACTTCCTGACCGGCGTGGGCGCCCTCCTGGAGCTGGCGCTGGTCAACGCGGCGATCGCGCAGGCCACGGC GGCCGGCTTCACGCCGATGCTGACCCCGGCACTGGTGCGCCCGCAGTCGATGGCCGGCACCGGCTTCCTCGGCCAGGCCG CCCAGGACGTCTACCACCTCGACAAGGACGACCTGTACCTGGTCGGCACGTCCGAGGTGCCGCTCGCCGCGTACCACATG GACGAGATCCTGGACGGGGACCGCCTGCCGCTGCGCTACGCCGGCTTCTCGCCCTGCTTCCGCCGCGAGGCGGGCTCGCA CGGCAAGGACACCCGGGGCATCTTCCGCGTGCACCAGTTCGACAAGGTCGAGATGTTCTCCTACGTCCTCCCCGAGGACT CGCAGGCCGAGCACCAGCGCCTGCTGGAGTGGGAGAAGCAGTGGCTGACGTCGCTGGAGCTGCCGTTCCGGGTGATCGAC GTGGCCTCGGCCGACCTGGGCTCCTCGGCCGCGCGCAAGTACGACTGCGAGGCGTGGATCCCGACCCAGGGCAAGTACCG CGAGCTGACCTCGACCTCGGACTGCACCGAGTTCCAGTCCCGCCGGCTGTCGATCCGCGTCCGCGAGGGCAAGAAGGTGC GCCCGCTGGCCACGCTCAACGGCACGCTGTGCGCCGTTCCGCGCACCATCGTGGCGATCCTGGAGAACCACCAGCAGGCC GACGGCTCGGTCCGCGTTCCCGAGGTGCTGCGCCCGTACCTGGGCGGCCGGGAGGTCCTGGAGCCGGTGGCCAAGTGA Protein sequence : MIDLRLLREDPDRVRASQRARGEDVALVDSLLSADERRRSSGVRFDELRAEQKGLGKLIGKAAGDEKAELLKRAEQLKTD VKAADAERDAADAETQELLQRLGNLVHPDVPVGGEEDFVTLETHGTHRDFAAEGFEPRDHLELGQLLGAIDVERGAKVSG SRFYFLTGVGALLELALVNAAIAQATAAGFTPMLTPALVRPQSMAGTGFLGQAAQDVYHLDKDDLYLVGTSEVPLAAYHM DEILDGDRLPLRYAGFSPCFRREAGSHGKDTRGIFRVHQFDKVEMFSYVLPEDSQAEHQRLLEWEKQWLTSLELPFRVID VASADLGSSAARKYDCEAWIPTQGKYRELTSTSDCTEFQSRRLSIRVREGKKVRPLATLNGTLCAVPRTIVAILENHQQA DGSVRVPEVLRPYLGGREVLEPVAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| serS | YP_003446791.1 | seryl-tRNA synthetase | Not tested | The aminoglycoside resistance gene cluster | Protein | 2e-66 | 43 |
