Gene Information

Name : SCH22A.19c (SCO3741)
Accession : NP_627932.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 4112648 - 4113418 bp
Length : 771 bp
Strand : -
Note : SCH22A.19c, probable response regulator, len: 256 aa; similar to TR:P74922 (EMBL:U67196) Thermotoga maritima DNA-binding response regulator DrrA, 239 aa; fasta scores: opt: 664 z-score: 686.2 E(): 8.4e-31; 45.3% identity in 234 aa overlap and to SW:AFQ1_S

DNA sequence :
GTGCTCGAACCGACGGCCGCCCCCGCCGCCGCGGCGGAGCCCGCGGCCGCCACCGCCCCCGCCGTCGCCCCCGCGGCCGA
CCCCGCCCGGATCCTCGTCGTGGACGACGATCCCACCGTCGCCGAGGTCGTGGCCGGGTACCTCGACCGGGCCGGTTACC
GTGTCGACCGGGCCGGTGACGGGCCGGAGGCGCTCGCGCGGGCCGCCGGGCACCGTCCCGACCTGGTGGTGCTCGACCTG
ATGCTGCCCGGCATGGACGGGCTGGAGGTGTGCCGTCGGCTGCGCGGCCAGGGGCCGGTGCCGGTCATCATGCTGACCGC
CCGGGGCGACGAGGACGACCGCGTCCTCGGACTGGAGGTCGGCGCCGACGACTACGTGACCAAGCCGTTCAGCCCGCGGG
AGCTGGTGCTGCGGGTGGAGTCCGTCCTGCGCCGCACCCGGCCCGCCCCGGCGCCGCGCCCGCCGTCCGCGGCCGGTCTG
ACCGCCGACCCGGCCGCCCGCAGGGCCACCAAGGACGGCGCCGAACTGGCGCTGACCCTGCGCGAGTTCGACCTGCTCGC
CTTCTTCCTGCGGCATCCGGGACGGGCGTTCGCCCGGGAGGAGCTGATGCGTGAGGTGTGGGGCTGGGACTTCGGGGACC
TGTCCACCGTCACCGTCCACGTCCGGCGGCTGCGCGGCAAGGTCGAGGACGATCCGGCCCGGCCCCGGCTGATCCAGACG
GTGTGGGGCGTGGGCTACCGCTTCGACCCCGCGGGCCGGGAGGCGGACTGA

Protein sequence :
MLEPTAAPAAAAEPAAATAPAVAPAADPARILVVDDDPTVAEVVAGYLDRAGYRVDRAGDGPEALARAAGHRPDLVVLDL
MLPGMDGLEVCRRLRGQGPVPVIMLTARGDEDDRVLGLEVGADDYVTKPFSPRELVLRVESVLRRTRPAPAPRPPSAAGL
TADPAARRATKDGAELALTLREFDLLAFFLRHPGRAFAREELMREVWGWDFGDLSTVTVHVRRLRGKVEDDPARPRLIQT
VWGVGYRFDPAGREAD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-28 42
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 3e-37 42
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 2e-36 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SCH22A.19c NP_627932.1 response regulator NC_012469.1.7685629. Protein 1e-41 47
SCH22A.19c NP_627932.1 response regulator AE000516.2.gene3505. Protein 3e-42 46
SCH22A.19c NP_627932.1 response regulator CP000034.1.gene3671. Protein 6e-41 43
SCH22A.19c NP_627932.1 response regulator NC_002952.2859905.p0 Protein 1e-42 43
SCH22A.19c NP_627932.1 response regulator NC_002758.1121668.p0 Protein 1e-42 43
SCH22A.19c NP_627932.1 response regulator NC_009641.5332272.p0 Protein 1e-42 43
SCH22A.19c NP_627932.1 response regulator NC_013450.8614421.p0 Protein 1e-42 43
SCH22A.19c NP_627932.1 response regulator NC_007793.3914279.p0 Protein 1e-42 43
SCH22A.19c NP_627932.1 response regulator NC_003923.1003749.p0 Protein 1e-42 43
SCH22A.19c NP_627932.1 response regulator NC_002745.1124361.p0 Protein 1e-42 43
SCH22A.19c NP_627932.1 response regulator NC_009782.5559369.p0 Protein 1e-42 43
SCH22A.19c NP_627932.1 response regulator NC_002951.3237708.p0 Protein 1e-42 43
SCH22A.19c NP_627932.1 response regulator NC_007622.3794472.p0 Protein 1e-42 43
SCH22A.19c NP_627932.1 response regulator BAC0197 Protein 2e-30 43
SCH22A.19c NP_627932.1 response regulator NC_011595.7057856.p0 Protein 1e-37 42
SCH22A.19c NP_627932.1 response regulator NC_010410.6002989.p0 Protein 1e-37 42
SCH22A.19c NP_627932.1 response regulator NC_010400.5986590.p0 Protein 6e-38 42
SCH22A.19c NP_627932.1 response regulator BAC0111 Protein 7e-35 41
SCH22A.19c NP_627932.1 response regulator BAC0638 Protein 3e-27 41
SCH22A.19c NP_627932.1 response regulator BAC0125 Protein 2e-31 41
SCH22A.19c NP_627932.1 response regulator BAC0083 Protein 2e-34 41
SCH22A.19c NP_627932.1 response regulator NC_012469.1.7686381. Protein 7e-40 41
SCH22A.19c NP_627932.1 response regulator AF155139.2.orf0.gene Protein 2e-41 41
SCH22A.19c NP_627932.1 response regulator CP000647.1.gene2531. Protein 3e-33 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SCH22A.19c NP_627932.1 response regulator VFG1390 Protein 2e-34 47
SCH22A.19c NP_627932.1 response regulator VFG1389 Protein 2e-29 44
SCH22A.19c NP_627932.1 response regulator VFG0596 Protein 5e-29 42
SCH22A.19c NP_627932.1 response regulator VFG1563 Protein 2e-37 42
SCH22A.19c NP_627932.1 response regulator VFG1702 Protein 1e-36 42