Gene Information

Name : SCH35.26 (SCO3698)
Accession : NP_627890.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Resistance
Product : heavy metal resistance membrane protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0798
EC number : -
Position : 4077583 - 4078692 bp
Length : 1110 bp
Strand : -
Note : SCH35.26, possible heavy metal resistance membrane protein, len: 369aa; similar to many hypothetical proteins eg. TR:P71942 (EMBL:Z80225) from Mycobacterium tuberculosis (498 aa) fasta scores; opt: 1731, z-score: 2029.9, E(): 0, (73.8% identity in 362 aa

DNA sequence :
GTGACCCGCACCGAAGCCCCCGCGACGACCGCGGAGGAGCCCTCCGTCGTCGCGAAACTGTCGACGCTCGACCGCTTCCT
CGCCGTCTGGATCCTCATCGCCATGGCCGTCGGGCTCGGCCTGGGGCGGGCCGTCCCGGGCCTCGACGACGCCCTCGCCA
AGGTCGAGATCGGCGGCATCTCCCTGCCGATCGCCGTCGGCCTGCTGGTCATGATGTATCCGGTCCTGGCCAAGGTCCGC
TACGACAAGCTCGACGCCGTCACCGGCGACCGCAGGCTCATGGCCTCGTCGCTGGTGATCAACTGGATCGTCGGCCCGGC
GGTGATGTTCGCGCTCGCGTGGATCTTCCTGCCGGACCTGCCCGAGTACCGCACCGGCCTGATCATCGTGGGCCTGGCCC
GCTGCATCGCCATGGTCATCATCTGGAACGACCTGGCCTGCGGAGACCGCGAGGCCGCCGCTGTCCTGGTCGCGCTGAAC
TCGGTCTTCCAGGTGCTGGCGTTCGGCCTGCTCGGCTGGTTCTACCTCGACCTGCTGCCCGGCTGGCTCGGCCTGGGCGA
CGGCGAGCACCTGGACATCTCCATGTGGAAGATCGCCCTGAACGTCGTCGTCTTCCTCGGCGTCCCGCTGCTGGCCGGCT
TCCTCACCCGCCGCATCGGCGAGAAGCGGCTCGGCCGCGAGAGGTACGAGTCCCGGTTCCTGCCGAAGATCGGGCCCTGG
GCGCTCTACGGCCTCCTCTTCACGATCGTCATCCTCTTCGCCCTCCAGGGCAAGACCATCACCTCGCAGCCCTTCGACGT
CGCCCGCATCGCACTGCCGCTGCTGGTGTACTTCGCCGTGATGTGGGCCGGGACCTTCCTGCTGGGCAAGGCGATCGGCC
TCGCCTACGACCGCACGGCCACCCTCGCCTTCACCGCCGCCGGCAACAACTTCGAGCTGGCCATCGCCGTCGCCATCGCC
ACCTTCGGCGTCACCTCCGGCCAGGCCCTGTCCGGCGTCGTGGGACCGCTCATCGAGGTGCCCGTCCTGATCGGCCTGGT
CTACGTGTCCCTGGCCTGGCGCAGGAAGTTCACCCCGTCCGCGCCGGCCACTGAGGGCAGGGGCCACTGA

Protein sequence :
MTRTEAPATTAEEPSVVAKLSTLDRFLAVWILIAMAVGLGLGRAVPGLDDALAKVEIGGISLPIAVGLLVMMYPVLAKVR
YDKLDAVTGDRRLMASSLVINWIVGPAVMFALAWIFLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAAAVLVALN
SVFQVLAFGLLGWFYLDLLPGWLGLGDGEHLDISMWKIALNVVVFLGVPLLAGFLTRRIGEKRLGRERYESRFLPKIGPW
ALYGLLFTIVILFALQGKTITSQPFDVARIALPLLVYFAVMWAGTFLLGKAIGLAYDRTATLAFTAAGNNFELAIAVAIA
TFGVTSGQALSGVVGPLIEVPVLIGLVYVSLAWRRKFTPSAPATEGRGH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB ADZ05767.1 arsenic resistance protein Not tested AbaR11 Protein 2e-58 51
arsB CAJ77016.1 transmembrane protein of arsenate pump Not tested AbaR1 Protein 2e-75 51
arsB AFC76433.1 ArsB Not tested AbaR5 Protein 2e-75 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SCH35.26 NP_627890.1 heavy metal resistance membrane protein BAC0573 Protein 3e-77 53
SCH35.26 NP_627890.1 heavy metal resistance membrane protein BAC0004 Protein 4e-59 45