Gene Information

Name : SC66T3.07 (SCO3596)
Accession : NP_627791.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Resistance
Product : D-alanine:D-alanine dipeptidase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG2173
EC number : -
Position : 3973354 - 3973962 bp
Length : 609 bp
Strand : +
Note : SC66T3.07, probable D-alanine:D-alanine dipeptidase, len: 202 aa; highly similar to e.g. vanXst (EMBL:AF039028) Streptomyces toyocaensis D-ala-D-ala dipeptidase (208 aa), fasta scores; opt: 1137 z-score: 1354.4 E(): 0, 77.6% identity in 201 aa overlap. Al

DNA sequence :
ATGACCGGGGACTTCGCCTTCGTGGACGAGCTGGTGTCCGGAATCCGGTGGGACGCCAAGTACGCCACCTGGGACAACTT
CACCGGCAAACCCGTGGACGGATACCTGGCGAACCGGATCGTCGGCACCAAGGCCCTGTGCGCGGCTCTGGGAAGGGCGC
AAGAACGGGCCGAAGACCTCGGCTTCGGGCTGCTCCTGTGGGACGGCTACCGCCCGCAGCGCGCCGTGGACTGCTTCCTC
CGCTGGTCACAACAGCCGGAGGACGGCCGGACGAAGGCCCGGCACTACCCGAACATCGGCAGGGCCGAGATGTTCGACAG
GGGGTACGTGGCCGCCAGGTCGGGCCACAGCCGAGGTGCCACCGTCGACTTGACGCTGTACCACCTGACCACCGGTGAAC
TCGCGGCCATGGGCGGCGGCCACGACCTCATGGACCCGATATCGCATCACGACGCCCGAGACGTCCCGCGGGCCGAGGCG
GCGAACCGACGGCATCTGCGCTCGATCATGGCCGCCTGCGGTTTCGCCTCATACGCCTGCGAGTGGTGGCACTACACGCT
GAAGGAGGAGCCGCACCCGGACACCTACTTCGACTTTCCCATCGCGTAG

Protein sequence :
MTGDFAFVDELVSGIRWDAKYATWDNFTGKPVDGYLANRIVGTKALCAALGRAQERAEDLGFGLLLWDGYRPQRAVDCFL
RWSQQPEDGRTKARHYPNIGRAEMFDRGYVAARSGHSRGATVDLTLYHLTTGELAAMGGGHDLMDPISHHDARDVPRAEA
ANRRHLRSIMAACGFASYACEWWHYTLKEEPHPDTYFDFPIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanXB YP_008394260.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 5e-63 64
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 8e-64 64

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SC66T3.07 NP_627791.1 D-alanine:D-alanine dipeptidase U82965.2.orf32.gene. Protein 1e-79 78
SC66T3.07 NP_627791.1 D-alanine:D-alanine dipeptidase AF310956.2.orf6.gene Protein 2e-63 64
SC66T3.07 NP_627791.1 D-alanine:D-alanine dipeptidase AF130997.1.orf5.gene Protein 3e-63 64
SC66T3.07 NP_627791.1 D-alanine:D-alanine dipeptidase U35369.1.gene7.p01 Protein 5e-64 64
SC66T3.07 NP_627791.1 D-alanine:D-alanine dipeptidase AE016830.1.gene2249. Protein 3e-64 64
SC66T3.07 NP_627791.1 D-alanine:D-alanine dipeptidase AF155139.2.orf6.gene Protein 3e-64 63
SC66T3.07 NP_627791.1 D-alanine:D-alanine dipeptidase NC_014475.1.orf4.gen Protein 1e-62 61
SC66T3.07 NP_627791.1 D-alanine:D-alanine dipeptidase FJ349556.1.orf5.gene Protein 2e-62 61
SC66T3.07 NP_627791.1 D-alanine:D-alanine dipeptidase NC_005054.2598281.p0 Protein 1e-62 61
SC66T3.07 NP_627791.1 D-alanine:D-alanine dipeptidase M97297.gene.p01 Protein 1e-62 61