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Name : dldh; SC66T3.05 (SCO3594) Accession : NP_627789.1 Strain : Streptomyces coelicolor A3(2) Genome accession: NC_003888 Putative virulence/resistance : Resistance Product : D-lactate dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1052 EC number : - Position : 3971293 - 3972306 bp Length : 1014 bp Strand : + Note : SC66T3.05, dldh, probable D-lactate dehydrogenase, len: 337 aa; highly similar to many e.g. TR:O33805 (EMBL:U8296) Streptomyces toyocaensis D-lactate dehydrogenase (330 aa), fasta scores; opt: 1470 z-score: 1711.8 E(): 0,71.4% identity in 318 aa overlap. DNA sequence : ATGACCTTCTCCTCGACCTCCTCGGCCCCTCCACCGTCACCGCTCCTCCCGGCAACGAGAATCACGGTTTACGGCTGCGG GCGGGACGAGGCCGCCTTGTTCCGCCGGACGGCACCCCGTTTCGGCGTCGAGGCGACTCTCACGGAGGCCGCCGTATCCG AAGAGAACGCCGAGATGGCGGCCGGAAACCAATGCATCAGCATTGACCACAAGACCCCGGTCACACCTGCCACTCTCCGC GCTCTCCACCGGGCCGGCGTGACGTACATATCCACCCGGAGTATCGGTTACAACCACATCGATGTGACATACGCGGCCGG CGTGGGGATATCCGTCGAGAACGTCACCTACTCCCCCGCCGGCGTGGCCGACTACACCCTGATGCTCATGCTGATGGCGG TGCGCAACGCGAAATCCACCGTCCGCCGCGCGGAGCTGCACGACTACCGGCTGAACGAGATACGCGGTAAGGAGCTGCGC GACCTGACCGTCGGAGTGATCGGGACGGGGCGTATCGGTGCGGCGGTCGTGGACAGGCTGCGGGGTTTTGGCTCCCGGGT ACTGGCCTACGGAAAACGGCCCACCATCGCGGCAGATTACGTCTCTCTCGACGAGTTGCTGCGGTCGAGCGACATCGTGT CGCTGCACGTACCGCTGACCCCGGACACGCATCACCTTCTCGATCAAAGCCGTATCCGGCGGATGAAAAGTGGCGCTTTC GTCATCAACACCGGACGCGGCCCGCTCATCGACACCGAAGCGCTGGTACCGGCGTTGGAGAGCGGCAGGTTGAGCGGTGC GGCGCTGGATGTCATCGAGGGCGAGGAAGGGATCTTCTACGCCGACTGCAGAAACAGAACCATCGAAAGCACGTGGCTCC CGCGGCTGCAGAAAATGCCGAACGTACTCATCAGCCCGCACACCGCCTATTACACCGACCACGCCCTGATGGACACGGTC GAGAACTCCATCATCAACTGCCTTAATTTCGGAAGCAGGAAACAGCATGGCTGA Protein sequence : MTFSSTSSAPPPSPLLPATRITVYGCGRDEAALFRRTAPRFGVEATLTEAAVSEENAEMAAGNQCISIDHKTPVTPATLR ALHRAGVTYISTRSIGYNHIDVTYAAGVGISVENVTYSPAGVADYTLMLMLMAVRNAKSTVRRAELHDYRLNEIRGKELR DLTVGVIGTGRIGAAVVDRLRGFGSRVLAYGKRPTIAADYVSLDELLRSSDIVSLHVPLTPDTHHLLDQSRIRRMKSGAF VINTGRGPLIDTEALVPALESGRLSGAALDVIEGEEGIFYADCRNRTIESTWLPRLQKMPNVLISPHTAYYTDHALMDTV ENSIINCLNFGSRKQHG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| EF2295 | NP_815952.1 | D-specific alpha-keto acid dehydrogenase | Not tested | Not named | Protein | 2e-95 | 61 |
| vanHB | YP_008394258.1 | VanH protein, D-specific alpha-keto acid dehydrogenase | Not tested | Not named | Protein | 3e-94 | 60 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| dldh; SC66T3.05 | NP_627789.1 | D-lactate dehydrogenase | NC_014475.1.orf2.gen | Protein | 6e-100 | 62 |
| dldh; SC66T3.05 | NP_627789.1 | D-lactate dehydrogenase | NC_005054.2598279.p0 | Protein | 6e-100 | 62 |
| dldh; SC66T3.05 | NP_627789.1 | D-lactate dehydrogenase | AF155139.2.orf4.gene | Protein | 7e-98 | 62 |
| dldh; SC66T3.05 | NP_627789.1 | D-lactate dehydrogenase | U35369.1.gene5.p01 | Protein | 6e-96 | 61 |
| dldh; SC66T3.05 | NP_627789.1 | D-lactate dehydrogenase | AF310956.2.orf4.gene | Protein | 6e-95 | 60 |
| dldh; SC66T3.05 | NP_627789.1 | D-lactate dehydrogenase | FJ349556.1.orf3.gene | Protein | 4e-95 | 58 |
| dldh; SC66T3.05 | NP_627789.1 | D-lactate dehydrogenase | AF130997.1.orf3.gene | Protein | 9e-85 | 56 |
