Gene Information

Name : SCE94.24c (SCO3373)
Accession : NP_627581.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Virulence
Product : Clp-family ATP-binding protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3736431 - 3738956 bp
Length : 2526 bp
Strand : -
Note : SCE94.24c, probable Clp-family ATP-binding protease, len: 841aa; highly similar to many egs. SW:MECB_BACSU MecB/ClpC pleiotropic regulator controlling competence gene expression and growth at high temperature in Bacillus subtilis (810 aa) fasta scores; op

DNA sequence :
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTGATCCACGAGGGTGAGGGTGTCGCCGCCAAGGCCCTTGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGCCAGGGCCAGCAGGCCCCGTCCGGCCACATCCCCTTC
ACCCCCCGTGCCAAGAAGGTTCTGGAGCTGTCGCTCCGCGAGGCCCTCCAGCTGGGCCACAACTACATCGGCACGGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCCCAGGTCCTGGTCAAGCTGGGCGCAGATCTGAACCGGG
TGCGGCAGCAGGTCATCCAGCTGCTCTCCGGTTACCAGGGCAAGGAGACCGCCACCGCCGGCGGTCCTGCGGAGGGCACC
CCCTCCACGTCCCTGGTCCTCGACCAGTTCGGCCGGAACCTCACCCAGGCCGCTCGCGAGTCCAAGCTCGACCCGGTCAT
CGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACGAAGAACAACCCGGTGCTGATCGGTGAGC
CCGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTCGCGCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAGGAC
AAGCACCTCTACACCCTGGACCTCGGTGCCCTGGTCGCCGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAAGAA
GGTGCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTGGTCGGTGCCGGTGCCG
CCGAGGGCGCCATCGACGCCGCGTCGATCCTCAAGCCGATGCTGGCCCGCGGTGAGCTCCAGACCATCGGTGCGACCACG
CTGGACGAGTACCGCAAGCACCTGGAGAAGGACGCGGCCCTCGAGCGCCGCTTCCAGCCGATCCAGGTCGCGGAGCCGTC
GCTGCCGCACACGATCGAGATCCTCAAGGGCCTGCGCGACCGCTACGAGGCCCACCACCGCGTCTCCATCACGGACGAGG
CCCTGGTCCAGGCGGCGACGCTCGCCGACCGCTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGAC
GAGGCCGGATCCCGGATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTCCGCGAGTTCGACGAGAAGATCGCCGGCGT
CCGCCGCGACAAGGAGTCCGCGATCGACTCGCAGGACTTCGAGAAGGCCGCTTCCCTCCGCGACAAGGAGAAGCAGCTCC
TGGCCGCCAAGGCCAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCGGAGGTGGACGGCGAGCTGATC
GCCGAGGTCCTCGCCACGGCGACCGGCATCCCGGTCTTCAAGCTCACGGAGGAGGAGTCGTCCCGCCTGCTGCGCATGGA
GGACGAGCTCCACAAGCGGGTCATCGGCCAGAAGGACGCCGTCAAGGCGCTCTCCAAGGCGATCCGCCGTACCCGTGCCG
GCCTGAAGGACCCGAAGCGTCCCGGTGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACCGAGCTGTCCAAG
GCACTCGCCGAGTTCCTCTTCGGTGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACACGGT
CTCGCGCCTCTTCGGTTCGCCCCCCGGCTACGTGGGCTACGAGGAGGGCGGCCAGCTGACGGAGAAGGTCCGCCGCAAGC
CGTTCTCGGTCGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCGGACATCTTCAACAGCCTTCTCCAGATCCTGGAGGAC
GGTCGCCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGCACCCG
GGACATCTCCAAGGGCTTCAACCTCGGCTTCGCCGCCGCGGGCGACACGAAGTCCAACTACGAGCGCATGAAGAACAAGG
TCCAGGACGAGCTGAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGTGTCGACGACGTGGTCGTCTTCCCGCAGCTCAGC
CAGGACGACATCCTGCAGATCGTCGACCTGATGATCCAGAAGGTCGACGAGCGCCTCAAGGACCGGGACATGGGCATCGA
GCTCTCCCAGTCCGCCAAGGAGCTGCTGTCCAAGCGGGGCTACGACCCGGTGCTGGGCGCGCGTCCGCTGCGCCGCACGA
TCCAGCGCGAGGTCGAGGACTCGCTGTCGGAGAAGATCCTCTTCGGCGAGCTGCGTCCCGGTCACATCGTGGTCGTGGAC
ACCGAGGGCGAGGGCGACGCGGCGACCTTCACCTTCCGGGGTGAGGAGAAGTCGACCCTCCCCGACGTCCCGCCGATCGA
GCAGGCGGCGGGCGGCGCGGGGCCCAACCTGAGCAAGGAGGCCTAG

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKETATAGGPAEGT
PSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKD
KHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGELI
AEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQKDAVKALSKAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
ALAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILED
GRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAAGDTKSNYERMKNKVQDELKQHFRPEFLNRVDDVVVFPQLS
QDDILQIVDLMIQKVDERLKDRDMGIELSQSAKELLSKRGYDPVLGARPLRRTIQREVEDSLSEKILFGELRPGHIVVVD
TEGEGDAATFTFRGEEKSTLPDVPPIEQAAGGAGPNLSKEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SCE94.24c NP_627581.1 Clp-family ATP-binding protease VFG0079 Protein 0.0 62
SCE94.24c NP_627581.1 Clp-family ATP-binding protease VFG0080 Protein 6e-152 52