Gene Information

Name : SCJ9A.32 (SCO0253)
Accession : NP_624585.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Resistance
Product : TetR family transcriptional regulator
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 242194 - 242766 bp
Length : 573 bp
Strand : +
Note : SCJ9A.32, probable tetR-family transcriptional regulator, len: 190 aa; similar to many e.g. SW:TER1_ECOLI TetR tetracycline resistance repressor from Escherichia coli (216 aa) fasta scores; opt: 501, z-score: 616.1, E(): 5.9e-27, (44.5% identity in 200 aa

DNA sequence :
GTGACCAAGATGAACCGGGAGACGGTGATCACCGAGGCGCTCGACCTGCTCGACGAGGTGGGACTGGACGGCGTCAGCAC
CCGGCGGCTGGCGAAGCGCCTGGGTGTCGAGCAGCCGTCGCTGTACTGGTACTTCCGCACCAAGAGGGATCTGCTGACGG
CCATGGCGCAGGCCGCCATGGCCCCGCACGCGGCCGAACCGCTGCCGGAGCCGGGCGAGGACTGGCACGGCTGGTTCCTG
CGGAACACGCGCAGTTTCAGGCGCACTCTGCTCGCCCGCCGTGACGGTGCACGCCTCCACGCCGGCAGCAGACCCACCGC
CGACCTCGACAGGGTCCGCCGCAAGATGGACTTCCTCGTCGCGTCCGGGGTGCCCGAGCGCCACGCGCAGATGGCGATGC
TCGCGGCCGGCCGCTTCACCGTCGGCTGCGTCCTGGAGGAGCAGGCGGAGACCGGCGCCGGTGACACGGCGGACCTCCCG
GCCGATGTGCCGGAAATCGATCACGAGTCGGCGTTCGAGGCGGGGCTGGCCCTCATCACGGACGGGCTGGTCCGGCATGT
GGACGCGAGGTAG

Protein sequence :
MTKMNRETVITEALDLLDEVGLDGVSTRRLAKRLGVEQPSLYWYFRTKRDLLTAMAQAAMAPHAAEPLPEPGEDWHGWFL
RNTRSFRRTLLARRDGARLHAGSRPTADLDRVRRKMDFLVASGVPERHAQMAMLAAGRFTVGCVLEEQAETGAGDTADLP
ADVPEIDHESAFEAGLALITDGLVRHVDAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetR ABZ01841.1 TetR Not tested SGI2 Protein 2e-19 46
tetR CAJ77033.1 Tetracycline repressor protein Not tested AbaR1 Protein 2e-19 46
tetR(G) AGK06973.1 TetR(G) Not tested SGI1 Protein 2e-19 46
tetR(G) AGK07103.1 TetR(G) Not tested SGI1 Protein 2e-19 46
tetR AAK02050.1 tetracycline resistance regulator protein Not tested SGI1 Protein 2e-19 46
tetR(A) ACK44536.1 TetR(A) Not tested SGI1 Protein 1e-26 45
tetR(A) AGK07026.1 TetR(A) Not tested SGI1 Protein 1e-26 45
tetR YP_006098395.1 tetracycline repressor Not tested Tn2411 Protein 2e-26 45
tetR(A) AGK07084.1 TetR(A) Not tested SGI1 Protein 1e-26 45
tetR(A) ACN81010.1 repressor protein Not tested AbaR5 Protein 1e-26 45
tetR CAJ77065.1 Tetracycline repressor protein Not tested AbaR1 Protein 1e-26 45
tetR1 YP_005176239.1 tetracycline repressor protein Not tested ICEPmu1 Protein 3e-20 41
tetR2 YP_005176247.1 tetracycline repressor protein Not tested ICEPmu1 Protein 3e-20 41