Gene Information

Name : SCJ9A.29 (SCO0250)
Accession : NP_624582.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Resistance
Product : transcriptional regulator
Function : -
COG functional category : K : Transcription
COG ID : COG1309
EC number : -
Position : 239858 - 240523 bp
Length : 666 bp
Strand : +
Note : SCJ9A.29, possible transcriptional regulator, len: 221aa; similar to many tetR-family transcriptional regulators eg. SW:TER1_ECOLI TetR from Tn1721 of Escherichia coli (216 aa) fasta scores; opt: 429, z-score: 484.8, E(): 1.2e-19, (40.7% identity in 209 a

DNA sequence :
ATGAGCCTCCCGTCAAGCCGGACCCGAGGTCGGCCCGCCCGACTCGACCGGGCCCGCACCGTCCAAACCGCCCTCGACCT
GCTGAACGAGTCCGGCCTCGACACACTGACCATGCGCCGGCTCGCCCAGGCGATGGACGTCCAGGCCGGTGCGCTGTACC
GCTACTTCGCGGCCAAGCAGGACCTGCTCACCGCGATGGCCGAGCACATGGTCGACGGCGTCGCCGACGCCGCCGGGGCG
ACGGGGGACGGCGACTGGAGCGAGAGAACGGCGCGCCTCGCCCGCGCACTGCGCGCGGCTCTGCTCGCCCATCGCGACGG
CGCACGGGTCTTCGCCGGCACGCACGCGACCGGTCCGAACACCCTGCGCTTCGCCGACGGCCTCGTCGGCGTGCTGCGCG
AGGCGGGCTTCGGCGACGGCGACGCCGCACGGGCGCTGTACTCCGTGGCCAACTTCACCGTCGGCCACACGCTGGAGGAA
CAGGCCGCCCTCACGCCGGGGGGCGGTGGGCCCCTCGACGAGGCGACCCTGCGCGAGGCGGTGGCGGCAGGGACCTATCC
CCACCTCGCCGCAACCCTGCCGGTGCTCACCAGTACGGATTTCACGGCACACTTCGAGTTCGGGCTGCGGCTGCTCCTGG
ACGGACTGCGCGCCGTCCGGCAGTGA

Protein sequence :
MSLPSSRTRGRPARLDRARTVQTALDLLNESGLDTLTMRRLAQAMDVQAGALYRYFAAKQDLLTAMAEHMVDGVADAAGA
TGDGDWSERTARLARALRAALLAHRDGARVFAGTHATGPNTLRFADGLVGVLREAGFGDGDAARALYSVANFTVGHTLEE
QAALTPGGGGPLDEATLREAVAAGTYPHLAATLPVLTSTDFTAHFEFGLRLLLDGLRAVRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetR YP_006098395.1 tetracycline repressor Not tested Tn2411 Protein 2e-16 41
tetR(A) ACK44536.1 TetR(A) Not tested SGI1 Protein 2e-16 41
tetR(A) AGK07026.1 TetR(A) Not tested SGI1 Protein 2e-16 41
tetR(A) AGK07084.1 TetR(A) Not tested SGI1 Protein 2e-16 41
tetR CAJ77065.1 Tetracycline repressor protein Not tested AbaR1 Protein 2e-16 41
tetR(A) ACN81010.1 repressor protein Not tested AbaR5 Protein 3e-16 41