Gene Information

Name : SC4G6.12c; trpE3 (SCO2043)
Accession : NP_626303.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Unknown
Product : anthranilate synthase component I
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : -
Position : 2192224 - 2193732 bp
Length : 1509 bp
Strand : -
Note : with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine

DNA sequence :
ATGGACGTCACGCATGACATGGACCTCGACACCTTCCGCAAGCTCGCCGCCGACCGCCGGGTGATCCCGGTGAGCCGCAA
GCTCCTCGCCGACGGCGACACCCCGGTCGCGCTGTACCGCAAGCTCGCCGCCTCGCGCCCCGGCACCTTCCTGCTGGAGT
CCGCGGAGAACGGACGCTCCTGGTCCAGGTACTCCTTCGTCGGCGTCCGCAGCGCCGCCACCCTCACCGAGAAGGACGGC
CAGGCGCACTGGCAGGGCACCCCGCCCGTCGGCGTCCCCACCGACGGCGACCCGCTCGCCGCCCTGCGCGCCACCGTCGA
GGCCCTGCACACCCCGCGCGACCTCGCCCACGACCTGGGCCTGCCGCCCTTCACCGGCGGCATGGTGGGCTACCTCGGGT
ACGACATCGTGCGCCGCCTGGAGAAGGTCGGCCCGGGGGAGCGCGACGACCTGAAGCTGCCCGAGCTGACCATGCTGCTC
ACCAGCGACCTCGCCGTCATGGACCACTGGGAGGGCTCGGTCCTGCTGATCGCCAACGCGATCAACCACAACGACCTGGA
GACCGGCGTCGACGAGGCCTACGCCGACGCGATCGCCCGCCTCGACGTCATGGAGGCCGACCTCACGCGTGCCGTCGCCC
AGCCCCCGGCCGCGCTGCCCCCCTCCGAGCTGCCCGAGTACACCGCGCTGTGGGGCGGCCCCGACTTCCAGGACGCCGTC
GAGGACATCAAGGAGCGCATCCGCGCGGGCGAGGCCTTCCAGGTCGTCCCCTCCCAGCGCTTCGAGACGCCCTGCACGGC
GAGCGCCCTCGACGTCTACCGGGTCCTGCGGGCCACCAACCCCTCCCCGTACATGTACCTGCTCCGTCTCGACGGCTTCG
ACGTCGTCGGCTCGTCCCCCGAGGCGCTGGTCAAGGTCGAGGACGGGCGCGCCATGGTGCACCCCATCGCCGGTACCCGC
CCGCGCGGCGCCACCCCGCGGGAGGACCAGTCCCTCGCCGACGAACTGCTCGCCGACCCCAAGGAGCGCGCCGAGCACCT
GATGCTGGTCGACCTCGGCCGCAACGACCTCGGGCGCGTCTGCGAGCCCGGGTCCGTCGAGGTCGTCGACTTCATGTCCG
TCGAGCGGTACTCGCACGTCATGCACATCGTCTCGACGGTCACCGGCCGGGTCGCCCCGGGCCGCACCGCCTTCGACGTC
CTCACCGCCTGCTTCCCGGCCGGCACCCTCTCCGGCGCGCCCAAGCCGCGCGCCCTGCAGATCATCGACGAACTCGAGCC
CTCCCGGCGCGGCCTGTACGGCGGCTGCGTCGGCTACCTCGACTTCGCCGGCGACTCCGACACCGCCATCGCCATCCGCA
CCGCCCTGCTGCGCGACGGCACCGCCTACGTCCAGGCGGGCGCGGGCGTCGTCGCCGACTCCGACCCGGTCGCCGAGGAC
ACCGAGTGCCGCAACAAGGCGGCGGCCGTGCTGAGGGCCGTACACACGGCCAACCGGCTGGCGCAATAG

Protein sequence :
MDVTHDMDLDTFRKLAADRRVIPVSRKLLADGDTPVALYRKLAASRPGTFLLESAENGRSWSRYSFVGVRSAATLTEKDG
QAHWQGTPPVGVPTDGDPLAALRATVEALHTPRDLAHDLGLPPFTGGMVGYLGYDIVRRLEKVGPGERDDLKLPELTMLL
TSDLAVMDHWEGSVLLIANAINHNDLETGVDEAYADAIARLDVMEADLTRAVAQPPAALPPSELPEYTALWGGPDFQDAV
EDIKERIRAGEAFQVVPSQRFETPCTASALDVYRVLRATNPSPYMYLLRLDGFDVVGSSPEALVKVEDGRAMVHPIAGTR
PRGATPREDQSLADELLADPKERAEHLMLVDLGRNDLGRVCEPGSVEVVDFMSVERYSHVMHIVSTVTGRVAPGRTAFDV
LTACFPAGTLSGAPKPRALQIIDELEPSRRGLYGGCVGYLDFAGDSDTAIAIRTALLRDGTAYVQAGAGVVADSDPVAED
TECRNKAAAVLRAVHTANRLAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00338 YP_008207803.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR25 Protein 5e-85 45
BJAB0868_00342 YP_008211668.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR26 Protein 5e-85 45