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Name : pyk1; SC7H2.28c (SCO2014) Accession : NP_626275.1 Strain : Streptomyces coelicolor A3(2) Genome accession: NC_003888 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : - Position : 2156337 - 2157773 bp Length : 1437 bp Strand : - Note : SC7H2.28c, pyk1, pyruvate kinase, len: 478 aa; strongly similar to many e.g. SW:KPYK_CORGL pyruvate kinase from Corynebacterium glutamicum (475 aa) fasta scores; opt: 1800, z-score: 2008.1, E(): 0, (59.6% identity in 473 aa overlap). Contains Pfam match t DNA sequence : ATGCGCCGAGCAAAGATCGTCTGCACTCTTGGGCCCGCCACCGACTCGTACGACCAGATCAAGGACCTGGTCGACGCCGG AATGGACATCGCCCGCTTCAATTTCAGCCACGGCACCCACGCCGAACACGAAGAGCGCTACCACCGTGTCCGCAAGGCGT CCGACGAGACCGGCCGCAGCGTCGGTGCCCTCGCCGACCTTCAGGGCCCGAAGATCCGCCTCGGCCACTTCGGTGAAGGG CCCGTACTCCTTGAACGCGGCGACAGCTTCACCATCACCGTCGAGGAGGGCGTCGAGGGCGACCGCTACATCTGCGGCAC CACCTACGCGGGCCTGGCCGAGGACGTCACCCCCGGTGAGCGCGTCCTCGTCGACGACGGCAAGGTCTGCCTGGAGGTGA CCGGGGTCGACGGGACCCGGGTGCGGACGCGGGTGATCGAGGGCGGCATGGTCTCCGACCACAAGGGCCTCAACCTGCCC GGCGTCGCGGTGTCCGTGCCCGCCCTGTCGAAGAAGGACGAGGACGACCTGCGCTGGGCGCTGCGGGCCGGCTTCGACGT GGTCGCCCTCTCCTTCGTCCGCAGCGGACGCGACATCCTCGACGTGCACCGCATCATGGACGAGGAGGGCCGCCGCCTCC CCGTCATCGCCAAGGTCGAGAAGCCGCAGGCCGTGGAGAACATCGAGGACATCGTCGCGGCCTTCGACGGCATCATGGTC GCCCGGGGCGACCTCGGCGTCGAGATGCCCCTGGAACAGGTGCCGACCGTCCAGAAGCGCGCGGTGAAGCTGGCCAAGCG CAACGCCAAGCCGGTCATCGTCGCCACCCAGATGCTCGACTCGATGATCGACAACGCCCGCCCCACCCGCGCGGAGGCCT CCGACGTCGCCAACGCCGTCATCGACGGCACCGACGCCGTGATGCTCTCCGGCGAGACCAGCGTCGGCAAGCACCCCACC GACACCGTGCGCACGATGGCCCGGATCGTCGAAGCGGCCGAGGAGGACATCCTCGCCAAGGGACTCCCCCCGCTGACCGA ACGGAACAAGCCCCGCACCCAGGGCGGTGCGGTCGCCCGCGCCGCCGCCGAGATGGGCGACTTCCTCGGCGCCAAGTTCC TGGTCGCCTTCACCCAGTCCGGCGACACGGTCCGCCGCCTCTCCCGCTACCGCTCGCCCATTCCGCTGCTCGCCTTCACC CCGGAACCGGCGACCCGCTCCCAGCTGAGCCTGACCTGGGGTGTGGAGACCTTCCTCGGTCCGCACGCCGACTCCACGGA CGCGATGGTCGACCAGGTGGACGAGCTTCTCACCCGCTACGGACGCTGCGAAAAGGGCGACGTCGTGGTCATCACGGCCG GCTCACCGCCGGGGGTGTCCGGCACGACGAACCTGGTGCGTGTGCACCACATCGGGGAGGACGACATTCCCAAGTGA Protein sequence : MRRAKIVCTLGPATDSYDQIKDLVDAGMDIARFNFSHGTHAEHEERYHRVRKASDETGRSVGALADLQGPKIRLGHFGEG PVLLERGDSFTITVEEGVEGDRYICGTTYAGLAEDVTPGERVLVDDGKVCLEVTGVDGTRVRTRVIEGGMVSDHKGLNLP GVAVSVPALSKKDEDDLRWALRAGFDVVALSFVRSGRDILDVHRIMDEEGRRLPVIAKVEKPQAVENIEDIVAAFDGIMV ARGDLGVEMPLEQVPTVQKRAVKLAKRNAKPVIVATQMLDSMIDNARPTRAEASDVANAVIDGTDAVMLSGETSVGKHPT DTVRTMARIVEAAEEDILAKGLPPLTERNKPRTQGGAVARAAAEMGDFLGAKFLVAFTQSGDTVRRLSRYRSPIPLLAFT PEPATRSQLSLTWGVETFLGPHADSTDAMVDQVDELLTRYGRCEKGDVVVITAGSPPGVSGTTNLVRVHHIGEDDIPK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-77 | 42 |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 2e-77 | 42 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-77 | 42 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 4e-77 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pyk1; SC7H2.28c | NP_626275.1 | pyruvate kinase | VFG0479 | Protein | 5e-78 | 42 |
