Gene Information

Name : SCC22.17; tktA1 (SCO1935)
Accession : NP_626200.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2066713 - 2068800 bp
Length : 2088 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGAGCACCAAGCCGACCACCACAGACCTCGAGTGGACCGAACTGGACCAGCGGGCCGTGGACACCGCCCGCGTCCTGGC
CGCCGATGCCGTACAGAAGGTTGGCAACGGCCATCCGGGTACGGCGATGAGCCTGGCGCCCGCCGCCTACACCCTCTTCC
AGAAGGTGATGCGGCACGACCCCGCCGACGCGAACTGGGTCGGGCGCGACCGTTTCGTGCTGTCCGCGGGCCACTCGTCC
CTGACCCTCTACACCCAGCTGTACCTGGCCGGTTTCGGCCTGGAGCTGGCGGACCTGGAGTCCTTCCGCACCTGGGGCTC
CAAGACCCCCGGCCACCCGGAGTACGGCCACACCACGGGCGTGGAGACCACGACCGGCCCGCTGGGCCAGGGTGTCGCCA
ACGCGGTGGGCATGGCGATGGCCGCCCGCTACGAGCGCGGCCTGTTCGACCCGGAGGCCGCCGAGGGCGAGTCCCCGTTC
GACCACTTCGTCTACTGCATCGCCGGTGACGGCTGCCTCCAGGAGGGCATCTCCTCCGAGGCGTCCTCGACGGCCGGTCA
CCAGAAGCTCGGCAACCTGGTGCTCTTGTGGGACGACAACCACATCTCCATCGAGGGCGACACGGAGACCGCCGTCTCCG
AGGACACCTGCAAGCGGTACGAGGCGTACGGCTGGCACGTCCAGCGTGTCGCGCCGAAGCCGGACGGCGACCTGGACCCG
AACGCGATCTACGACGCGATCGAGGCGGCCAAGAAGGTCACCGACCGCCCCTCCTTCATCGCGATGCGCTCGATCATCGC
CTGGCCCGCCCCGAACGCGCAGAACACCGAGGCCGCGCACGGCTCGGCGCTCGGCGACGACGAGGTCGCGGCGACCAAGC
GGGTCCTGGGCTTCGACCCGGAGAAGTCCTTCGAGGTCTCCGACGAGGTCATCGAGCACACCCGCAAGGCCCTGGAGAAG
GGGCAGGCGGCCCGCGCGGTGTGGGAGAAGTCCTTCCAGCAGTGGCGGGACAACAACCCGGAGCGCGCCGCCGAGTACGA
CCGCGTGGCCAAGGGTGAGCTGCCGGCGGGCTGGGAGGAGAAGATCCCGGTCTTCGAGGCGGGCAAGGGCCTGGCGACCC
GCGCCGCGTCCGGCAAGGTGCTCCAGGCGCTCGGCGCGGTGATCCCGGAGCTGTGGGGCGGATCGGCCGACCTCGCGGGC
TCGAACAACACGACGATCGACAAGACGTCGTCCTTCCTCCCGGCGGGCAACCCGCTGCCGGAGGCCGACCCGTACGGCCG
CACCATCCACTTCGGCATCCGCGAGCACGCGATGGCGGCGGAGATGAACGGCATCGCGCTGCACGGGAACACCCGCATCT
ACGGCGGAACGTTCCTGGTCTTCTCCGACTACATGCGCAACGCCGTGCGCCTGTCGGCCCTGATGCACCTGCCGGTGACG
TACGTGTGGACGCACGACTCCATCGGTCTGGGCGAGGACGGCCCGACCCACCAGCCGGTCGAGCACCTGGCCTCGCTGCG
CGCCATCCCGGGTCTGAACGTGGTCCGCCCGGCCGACGCCAACGAGACGGCGATCGCCTGGCGGGAGATCCTGCGCCGCT
GGACGAAGGAGTTCGGCAAGGGCCAGCCGCACGGTCTGGCGCTGACCCGCCAGGGTGTGCCGACGTACGAGCCGAACGAG
GACGCGGCCAAGGGCGGCTACGTGCTGTTCGAGGCGGAGGGCGGCGACGCCGAGGTCGTGCTCATCGCCACCGGTTCCGA
GGTGCACGTGGCCGTCGGGGCGCGTGAGCGGCTCCAGGCCGACGGCGTGCCGACCCGTGTGGTGTCCATGCCGTCCGTGG
AGTGGTTCGAGCAGCAGGACCAGGGGTACCGGGACAGCGTCCTGCCCCCGTCCGTGAAGGCCCGGGTCGCGGTCGAGGCC
GGGATCGGTCTGACCTGGCACAAGTACGTGGGAGACGCCGGCCGCATCGTCTCGCTGGAGCACTTCGGTGCTTCGGCGGA
CGCCAAGGTGCTCTTCAAGGAGTTCGGCTTCACCGCCGAGAACGTGGCCTCCGCCGCGCGGGAATCCCTGGCCGCGGCCC
AGCGCTGA

Protein sequence :
MSTKPTTTDLEWTELDQRAVDTARVLAADAVQKVGNGHPGTAMSLAPAAYTLFQKVMRHDPADANWVGRDRFVLSAGHSS
LTLYTQLYLAGFGLELADLESFRTWGSKTPGHPEYGHTTGVETTTGPLGQGVANAVGMAMAARYERGLFDPEAAEGESPF
DHFVYCIAGDGCLQEGISSEASSTAGHQKLGNLVLLWDDNHISIEGDTETAVSEDTCKRYEAYGWHVQRVAPKPDGDLDP
NAIYDAIEAAKKVTDRPSFIAMRSIIAWPAPNAQNTEAAHGSALGDDEVAATKRVLGFDPEKSFEVSDEVIEHTRKALEK
GQAARAVWEKSFQQWRDNNPERAAEYDRVAKGELPAGWEEKIPVFEAGKGLATRAASGKVLQALGAVIPELWGGSADLAG
SNNTTIDKTSSFLPAGNPLPEADPYGRTIHFGIREHAMAAEMNGIALHGNTRIYGGTFLVFSDYMRNAVRLSALMHLPVT
YVWTHDSIGLGEDGPTHQPVEHLASLRAIPGLNVVRPADANETAIAWREILRRWTKEFGKGQPHGLALTRQGVPTYEPNE
DAAKGGYVLFEAEGGDAEVVLIATGSEVHVAVGARERLQADGVPTRVVSMPSVEWFEQQDQGYRDSVLPPSVKARVAVEA
GIGLTWHKYVGDAGRIVSLEHFGASADAKVLFKEFGFTAENVASAARESLAAAQR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 5e-124 47
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 3e-122 46