Gene Information

Name : SCI51.25c (SCO1785)
Accession : NP_626056.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Virulence
Product : iron-siderophore uptake system ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 1908769 - 1909674 bp
Length : 906 bp
Strand : -
Note : SCI51.25c, probable iron-siderophore uptake system ATP-binding component, len: 301 aa; similar to many ATP-binding components from binding-protein-dependent iron uptake systems using a range of siderophores e.g. SW:FEPC_ECOLI (EMBL:X57471), fepC, Escheric

DNA sequence :
ATGAGCGCCGGCACCGGCCACCGCAGCGGGCCGAACAACCGAAGGAGCAACAGCAACGTGAACCGCCTGACCGCCGAGAA
CGTCACCCTCGCCTACGACCAGCGGGTCATCGCGGAGAAGCTGTCGGTGGAGATACCCGACAACTCCTTCACCGTGATCG
TCGGCCCGAACGCGTGCGGCAAGTCCACGCTGCTGCGCGCCCTGTCACGGATGCTCAGGCCGAGCCAGGGCCGGGTGCTG
CTCGACGGATCGGTCATCCAGTCGATGCCCGCCAAGCAGGTCGCCCGGACCCTCGGCCTGCTCCCGCAGTCCTCCATCGC
GCCCGACGGCATCACCGTCGGCGACCTCGTCGGCCGCGGCCGCTACCCGCACCAGGGAATCCTGCGTCAGTGGTCGACCG
AGGACGAGCGGGTGGTCCAGGAGTCGATGGCCCGGACCGGCATCTCGGAGCTGGCCGACCGCTACGTCGACGAACTCTCC
GGCGGACAGCGCCAGCGCGTGTGGATCGCCATGGCGCTGGCCCAGCAGACCCCGCTGCTGCTCCTCGACGAGCCGACGAC
GTACCTGGACATCCAGCACCAGATCGACGTCCTCGACCTGTGCGCGGAACTCCACGAGGAGCAGGGGCGCACCCTCGTGG
CCGTGCTGCACGACCTCAACCACGCCGCCCGCTACGCCACCCACCTCATCGCCCTGCGCGAGGGTCAGGTCATCGCCGAG
GGCGCGCCGAAGGACATCGTCACCGCCGACCTGGTCGAGCGGGTCTTCGGGCTGCGCTGCCAGGTCATCGACGATCCCGA
GACGGGTACGCCGCTGGTGGTGCCGGCCGCCCGCAAAGGGCGCACCAAGCAGGTGAACGAGCAGGTGACCGAGCAGGCGA
AGGCGGTCGCTACAGGAGCTTCCTGA

Protein sequence :
MSAGTGHRSGPNNRRSNSNVNRLTAENVTLAYDQRVIAEKLSVEIPDNSFTVIVGPNACGKSTLLRALSRMLRPSQGRVL
LDGSVIQSMPAKQVARTLGLLPQSSIAPDGITVGDLVGRGRYPHQGILRQWSTEDERVVQESMARTGISELADRYVDELS
GGQRQRVWIAMALAQQTPLLLLDEPTTYLDIQHQIDVLDLCAELHEEQGRTLVAVLHDLNHAARYATHLIALREGQVIAE
GAPKDIVTADLVERVFGLRCQVIDDPETGTPLVVPAARKGRTKQVNEQVTEQAKAVATGAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-64 53
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 3e-65 50
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 3e-65 50
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 3e-65 50
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 3e-65 50
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 4e-62 47
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 4e-62 47
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 7e-51 46
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-52 43
irp6C YP_005124377.1 ATP-binding protein Irp6C Virulence Not named Protein 1e-28 41
irp6C NP_938506.1 ATP-binding protein Irp6C Not tested Not named Protein 1e-28 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SCI51.25c NP_626056.1 iron-siderophore uptake system ATP-binding protein BAC0164 Protein 4e-51 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SCI51.25c NP_626056.1 iron-siderophore uptake system ATP-binding protein VFG0925 Protein 2e-80 61
SCI51.25c NP_626056.1 iron-siderophore uptake system ATP-binding protein VFG1042 Protein 4e-51 46