Gene Information

Name : guaB2; SCL6.18c (SCO1461)
Accession : NP_625742.1
Strain : Streptomyces coelicolor A3(2)
Genome accession: NC_003888
Putative virulence/resistance : Unknown
Product : inosine 5-monophosphate dehydrogenase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0516
EC number : 1.1.1.205
Position : 1558380 - 1559831 bp
Length : 1452 bp
Strand : -
Note : catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate

DNA sequence :
GTGCAGCACGTGCGTTTCCTCAATGACATCCAGCCCTCGTACGACCTGACGTACGACGACGTGTTCATGGTGCCGAGCCG
CTCCGCCGTCGGCTCCCGGCAGGGCGTGGACCTCGGCTCCCCGGACGGCACGGGCACCACGATCCCGCTGGTCGTCGCCA
ACATGACCGCCATCGCGGGCCGCCGGATGGCCGAGACGGTGGCCCGGCGCGGCGGCCTCGTGGTCATCCCGCAGGACATC
CCGATCGAGGTCGTCACCGACGTCGTCTCCTGGGTGAAGAGCCGCCACCACGTCCTGGACACCCCGATCGTGCTGGCCCC
GCACCAGACCGTCGCCGACGCGCTGGCCCTGCTGCCCAAGCGCGCGCACAACGCGGGCGTCGTCGTGGACGAGGACGGCA
AGCCGGTCGGCGTGGTCACCGACACCGACCTGAACGGCGTGGACCGCTTCACCCAGCTCGAGGAGGTCATGTCCAAGGAC
CTGATCCTCATCGACGCCGACCTGGACCCGCGCGAGGCCTTCAACACCCTCGACGCGGCCAACCGGCGCTACGCGCCCGC
CGTGGACAAGGACGGCCGTCTCGCCGGCATCCTCACCCGCAAGGGCGCGCTGCGCGCCACCCTGTACACCCCGGCCGTCG
ACGCACAGGGCAGGCTCCGCATCGCCGCCGCCGTCGGCATCAACGGCGACGTGGCCGGCAAGGCCAAGCAGCTCCTCGAC
GCGGGTGTGGACACCCTCGTCATCGACACCGCGCACGGCCACCAGGAATCGATGATCAGCGCCGTCAAGGTGGTGCGCGA
CCTCGACCCGCGGGTCCCGATCGTCGCGGGCAACATCGTCTCCGCCCAGGGTGTGCGCGACCTGATCGAGGCGGGCGCCG
ACATCATCAAGGTCGGCGTCGGCCCCGGTGCCATGTGCACCACCCGCATGATGACCGGCGTGGGCCGGCCGCAGTTCTCC
GCCGTCCTGGAGTGCGCCGCCGAGGCGAAGAAGTACGGCAAGCACGTGTGGGCCGACGGCGGCGTCCGCCACCCGCGCGA
CGTGGCGATGGCCCTCGCGGCCGGCGCCTCCAACGTGATGGTCGGCTCCTGGTTCGCGGGCACCTACGAGTCCCCGGGCG
ACCTCCAGCACGACGCCAACGGCCGCGCCTACAAGGAGTCCTTCGGCATGGCCTCCGCGCGCGCGGTGCGCAACCGCACC
TCGGAGGAGTCGGCGTACGACCGGGCCCGCAAGGCGCTGTTCGAGGAGGGCATCTCCACCTCGCGGATGTTCCTCGACCC
GGCCCGGCCCGGCGTCGAGGACCTGATCGACGCGATCATCGCGGGCGTCCGCTCGTCCTGCACCTACGCCGGGGCCGGCT
CCCTGGAGGAGTTCACGGAGAAGGCCATCGTCGGCATCCAGAGCGCCGCCGGTTACGCCGAGGGCAAGCCGCTGCACGCC
AGCTGGAGCTGA

Protein sequence :
MQHVRFLNDIQPSYDLTYDDVFMVPSRSAVGSRQGVDLGSPDGTGTTIPLVVANMTAIAGRRMAETVARRGGLVVIPQDI
PIEVVTDVVSWVKSRHHVLDTPIVLAPHQTVADALALLPKRAHNAGVVVDEDGKPVGVVTDTDLNGVDRFTQLEEVMSKD
LILIDADLDPREAFNTLDAANRRYAPAVDKDGRLAGILTRKGALRATLYTPAVDAQGRLRIAAAVGINGDVAGKAKQLLD
AGVDTLVIDTAHGHQESMISAVKVVRDLDPRVPIVAGNIVSAQGVRDLIEAGADIIKVGVGPGAMCTTRMMTGVGRPQFS
AVLECAAEAKKYGKHVWADGGVRHPRDVAMALAAGASNVMVGSWFAGTYESPGDLQHDANGRAYKESFGMASARAVRNRT
SEESAYDRARKALFEEGISTSRMFLDPARPGVEDLIDAIIAGVRSSCTYAGAGSLEEFTEKAIVGIQSAAGYAEGKPLHA
SWS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cpfrc_01479 YP_003783879.1 hypothetical protein Not tested PiCp 5 Protein 2e-154 63
Cp1002_1469 YP_005681736.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 1e-154 63
CpC231_1472 YP_005683835.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 3e-154 63
CpI19_1479 YP_005685921.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 3e-154 63