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Name : SCG11A.05; thcA (SCO1174) Accession : NP_625464.1 Strain : Streptomyces coelicolor A3(2) Genome accession: NC_003888 Putative virulence/resistance : Virulence Product : aldehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : - Position : 1237012 - 1238535 bp Length : 1524 bp Strand : + Note : SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% iden DNA sequence : ATGACCCGTTACGCGGCGCCCGGCACCGAGGGCGCGATCGTCTCCTATCAGTCGCGCTACGACCACTTCATCGGCGGCGA GTACGTGCCACCGGCGCGCGGGCAGTACTTCGAGAACCCGTCCCCGGTGAACGGCCTGCCGTTCACCGAGATCGCGCGCG GCACGGCCGACGACGTGGAACGGGCGCTCGACGCCGCGCACGAGGCCGCTCCGGGCTGGGGCCGTACCTCGGTGACCGAG CGTTCCGACATCCTCCTGAAGATCGCCGACCGCATGGAGGCGAACCTGGAGCGCCTGGCGGTCGCGGAGAGCTGGGAGAA CGGCAAGCCGGTGCGCGAGACTCTGGCGGCCGACATCCCCCTCGCCATCGACCACTTCCGCTACTTCGCGGGCGCGGTGC GCGCCCAGGAGGGCTCACTCGGCGAGATCGACGACGACACCGTGGCGTACCACTTCCACGAACCGCTGGGGGTCGTCGCC CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCCACCTGGAAGCTCGCGCCCGCCCTCGCCGCCGGCAACGCCGTGGT CCTGAAGCCCGCGGAGCAGACCCCGGCCTCGATCCACTACTGGCTGAGCCTGGTGGCGGACCTGCTGCCGCCCGGGGTCC TGAACGTCGTCAACGGCTTCGGGGTGGAGGCGGGCAAACCGCTCGCGTCGAGCCCCCGGGTGGCGAAGGTGGCGTTCACC GGCGAGACCACCACCGGGCGGCTGATCATGCAGTACGCCTCGGAGAACATCAAACCGGTCACGCTGGAGCTGGGCGGCAA GTCGCCGAACATCTTCTTCGAGGACGTCTGGGCGCGGGACGACGACTTCCGCGACAAGGCGCTCGAGGGCTTCACCATGT TCGCGCTCAACCAGGGGGAGGTCTGCACCTGTCCGTCCCGCGCGCTCGTCCAGCGGGGCGTCTACGCCGAGTTCATGGAG GCAGCCGTCGCGCGCACCGAGTTGATCAAGCCCGGTCACCCCCTGGACACCGACACGATGATCGGCGCCCAGGCCTCCAA CGACCAGTTGGAGAAGATCCTCTCCTACCTGGACATCGGCCGCCAGGAGGGCGCGAAGGTACTCACCGGTGGTGAGCGGA TCGAGCACGACGGCGAGTTGAAGGGCGGCTACTACGTCCAGCCGACGATCTTCGAGGGCCACAACCGCATGCGGATCTTC CAGGAGGAGATCTTCGGCCCGGTGGTGTCGGTGACGTCCTTCGACGACTTCGACGACGCCGTCAAGACCGCCAACGACAC CCTGTACGGCCTCGGCGCCGGGGTGTGGACCCGCGACATGAACACCGCGTACCGCGCGGGCCGCGCGATCCAGGCGGGAC GCGTGTGGACGAACTGCTACCACGCATACCCGGCGCACGCCGCCTTCGGCGGCTACAAGCAGTCGGGCATCGGCCGGGAG AACCACAAGATGATGCTGGAGCACTACCAGCAGACGAAGAACATTCTTTGTTCCTACAGCCCCAAGAAACTCGGGTTCTT CTAG Protein sequence : MTRYAAPGTEGAIVSYQSRYDHFIGGEYVPPARGQYFENPSPVNGLPFTEIARGTADDVERALDAAHEAAPGWGRTSVTE RSDILLKIADRMEANLERLAVAESWENGKPVRETLAADIPLAIDHFRYFAGAVRAQEGSLGEIDDDTVAYHFHEPLGVVA QIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPASIHYWLSLVADLLPPGVLNVVNGFGVEAGKPLASSPRVAKVAFT GETTTGRLIMQYASENIKPVTLELGGKSPNIFFEDVWARDDDFRDKALEGFTMFALNQGEVCTCPSRALVQRGVYAEFME AAVARTELIKPGHPLDTDTMIGAQASNDQLEKILSYLDIGRQEGAKVLTGGERIEHDGELKGGYYVQPTIFEGHNRMRIF QEEIFGPVVSVTSFDDFDDAVKTANDTLYGLGAGVWTRDMNTAYRAGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRE NHKMMLEHYQQTKNILCSYSPKKLGFF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 7e-146 | 61 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-151 | 59 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-151 | 59 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-151 | 59 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 5e-151 | 59 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| SCG11A.05; thcA | NP_625464.1 | aldehyde dehydrogenase | VFG0082 | Protein | 3e-146 | 61 |
