Gene Information

Name : TTE0668 (TTE0668)
Accession : NP_622330.1
Strain : Thermoanaerobacter tengcongensis MB4
Genome accession: NC_003869
Putative virulence/resistance : Virulence
Product : nucleoside-diphosphate sugar epimerase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 669876 - 671747 bp
Length : 1872 bp
Strand : +
Note : Best Blastp hit = gi|10176342|dbj|BAB07437.1| (AP001519) capsular polysaccharide biosynthesis [Bacillus halodurans], score 482, E-value 1.00E-135

DNA sequence :
ATGTGGAAAAACAAGAGAAAAATTTTATTATTGCTTATTGACATTATCCTATTGAATATAGCATATTTTCTAGCTTTTTA
TTTGCGCTTTGACTATAATATTCCCCACCAATATTTTCTCTTATACAAAAAAACCTTTTACATAGTAGTTACAGTGACTG
TCGTAACATTTATCTTTTTCAAACAATACAATAAAATCTGGAGATATGCAAGTTTACATGATATTATGGATTTAATTATT
TTTACTACCATTGGCAGCGCTATGGCTGCTTTTGTTTTACTATTTTTACAAATACATTTGCCACGTTCTATTTATCCTTT
ATACTGGTTTTTGAGTGCATTGCTAATAGGTGGAAGTCGTATTGCTTATAGAAGTTATATGGAAAATAGCAGTAAAGTTA
AAGTAAAGAATATAAAATACAAAAAAGTGTTAATAGTAGGTGCTGGAGATGCTGGGCGTATACTTGTAAGGGAGATAAAA
AATCATCCAGAAACAGGCCTTAAGCCTGTAGCAATAGTAGATGATGATGTGTCTAAATTACACAGAAGTATTGATGATGT
GCCTGTTGTGGGGAAAATTGATGATATTCAGGAAGTTATTACGGAGAAGGAAATTGATGAAGTTATTTTTGCTATCCCTT
CTGCGCCTAGAACTGTTTTGAAAAAAGTTATTGATAAATGTAGTGAAATGCGCATAAAAGTTAAGACATTGCCAGCTATT
TATGAGTTAGTTGATGGAACAATATCAATAAGTAGCATAAGGGATGTTGATATAAATGATTTGTTAGGTAGAGAACCTGT
CAAAATTGATTTAGAGGAAATAAGTAGCTACATAAAAGGTAAAAAAGTTATGGTTACAGGTGGAGGAGGGTCCATTGGGT
CTGAACTTTGCAGACAAATAGCCCGATTTTCACCCTCTCGCCTTATTATACTAGACATATACGAAAACAATATGTATGAA
GTAGAACAGGAATTAAAAAGAAAATACCCTGAACTTGATGTAATTTGCTTAGTCGCAAATATTAGAGAAGAAAAGAAGAT
AAATAAAATTTTTAGTGAGTATACTCCTGATATTGTTTTTCACGCAGCTGCTCATAAACATGTTCCACTAATGGAGGTAA
GTCCTCATGAAGCTATTAAAAACAATGTATATGGTACATTGAATCTTGTAAAAGTTTCTGACTTATATAATGTCAATCGC
TTTGTAATGATTTCGACAGATAAGGCTGTCAATCCTACGAGTGTGATGGGAGCTTCTAAGCGCATATGTGAGATGATAAT
TCAAGAATACGATAAAAAAAGTAAAACTGAGTTTGTTGCAGTGCGATTTGGAAATGTGTTGGGAAGCAATGGAAGCGTTA
TACCTCTTTTTAAAAAGCAGATTGCAGAAGGTGGACCTGTTACGGTGACTCATGAAGAAATTAAAAGATACTTTATGACA
ATACCAGAAGCTGTTCAGTTGGTTATACAAGCAGGGGCTATGGCAAAGGGCGGCGAAATATTTGTACTTGATATGGGTGA
ACCGGTTAAAATTATAGATTTAGCAAGAACGTTAATTCGGTTATCGGGTTTTGAGCCTGATGTAGATATACCTATTAAGA
TTATTGGTTTAAGACCAGGAGAGAAATTATTTGAGGAATTATTAATAAGTGATGATAAATACGTGTCGACGAAGCATGAG
AAAATTTTTATTGAAAAGCCCGTTTCTGTCGATTATGGGGATTTAATTTTAACATTGGAAAAATATAAAGATAAGATAGA
TGATATGGATGAAGATGAAATAAGAGAGTTTATAAAGTCCCTTGTGCCAGAGTATAATCCTGATTATCAGCGGTCCTTAA
TGGAAGAAGTTGCCGCTACTGAAATAGAATAG

Protein sequence :
MWKNKRKILLLLIDIILLNIAYFLAFYLRFDYNIPHQYFLLYKKTFYIVVTVTVVTFIFFKQYNKIWRYASLHDIMDLII
FTTIGSAMAAFVLLFLQIHLPRSIYPLYWFLSALLIGGSRIAYRSYMENSSKVKVKNIKYKKVLIVGAGDAGRILVREIK
NHPETGLKPVAIVDDDVSKLHRSIDDVPVVGKIDDIQEVITEKEIDEVIFAIPSAPRTVLKKVIDKCSEMRIKVKTLPAI
YELVDGTISISSIRDVDINDLLGREPVKIDLEEISSYIKGKKVMVTGGGGSIGSELCRQIARFSPSRLIILDIYENNMYE
VEQELKRKYPELDVICLVANIREEKKINKIFSEYTPDIVFHAAAHKHVPLMEVSPHEAIKNNVYGTLNLVKVSDLYNVNR
FVMISTDKAVNPTSVMGASKRICEMIIQEYDKKSKTEFVAVRFGNVLGSNGSVIPLFKKQIAEGGPVTVTHEEIKRYFMT
IPEAVQLVIQAGAMAKGGEIFVLDMGEPVKIIDLARTLIRLSGFEPDVDIPIKIIGLRPGEKLFEELLISDDKYVSTKHE
KIFIEKPVSVDYGDLILTLEKYKDKIDDMDEDEIREFIKSLVPEYNPDYQRSLMEEVAATEIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 9e-99 49
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-94 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TTE0668 NP_622330.1 nucleoside-diphosphate sugar epimerase VFG1300 Protein 1e-93 45
TTE0668 NP_622330.1 nucleoside-diphosphate sugar epimerase VFG0029 Protein 5e-79 44