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Name : leuS (TTE0324) Accession : NP_622012.1 Strain : Thermoanaerobacter tengcongensis MB4 Genome accession: NC_003869 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 341338 - 343797 bp Length : 2460 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : GTGGAGGATATGGCGTATTCAGTGGAGATTGATAGGAAATGGCAGAAAATCTGGGAAGAGACAAAACTTTACAAGTTTAA TCCTGAAAATGTGGACAAAAAGCTTTATTGTTTAGAGATGTTTCCGTACCCTTCAGGGGCAAAATTGCACATAGGTCACT GGTATAATTACGGTCCTACAGATTCATGGGCAAGAATGAAGAGGATGCAGGGCTATGAAGTATTCCACCCTATGGGGTTT GACGCCTTTGGCCTTCCTGCTGAAAATTATGCCATAAAGACAGGCATACACCCTTATGACTCGACAATGGAAAACATAAG GACCATGGAAAGACAACTCAGAGAAATGGGAGTCACTTTTGACTGGGACTATGAGATTATAACCTGTCTGCCAGAGTACT ATAAATGGACTCAGTGGATTTTCTTAAAACTTTATGAAGCAGGTCTTGCCTACAGAAAGAAAGCGCCTGTAAACTGGTGT CCCAGCTGCCAGACTGTTCTTGCAAACGAACAGGTAATTGATGGGAAATGCGAAAGGTGCGGAACTGAAGTTACAAAGAA AGAGCTTACTCAGTGGTTTTTCAAAATAACTGCCTATGCGGAAGAACTTTTAGAAAAATTAGATGATCTTGATTGGCCTG AAAAAACTAAAATGATGCAGAGGAACTGGATTGGAAAATCTGAGGGCGCAGAGATAGAGTTTAAAATTGATGGGAAAGAC TTGTCTTTTAGAGTTTTTACCACAAGGGCAGATACGCTGTTTGGAGCAACTTATGTGGTATTGGCTCCTGAGCATGAATT GGTGGATTTGATTACTACAGAGGAATATAAAGAGGCTGTGGAAGAATACAAAGAGTATGCCAAAAAGCAGAGTGAGATTG AGAGGCTTTCAACAGAAAAGGAAAAGACAGGAGTGTTTACAGGAGCGTACGCGATTCATCCGCTGACAGGTGAAAAACTC CCTATTTGGATAGCGGATTATGTGCTTGTAACTTACGGTACTGGATGTGTTATGGGAGTTCCTGGTCATGATGAAAGAGA CTATGAATTTGCGACAAAATACAATCTGCCTATAAAAAGAGTTATAAAAGGAGTTGGAGATGTAGACGACAGTTTGCCTT TTGTGGAATATGGAATTTTAGTAAATAGCGAAGAATTTACGGGGATGACATCTGAGGAAGCGCGAGTCAAAATAGTCGAA AAGTTGAAAGCAGAAGGGAAAGCAGAGTTTAAAGTAAATTATAGGATGAGGGACTGGCTTGTGTCCAGACAGAGGTACTG GGGAGCTCCCATTCCTATAATCCACTGCGAACGCTGTGGAATAGTGCCTGTGCCAGAAGAGGATTTACCTGTACTTTTGC CATATGATGTTGAGTTTGAGCCAACAGGAGAATCTCCTCTTAAAAAGCATGCAGGTTTTATGAATGTCACCTGCCCTAAG TGCGGAGGTCCGGCTTTAAGAGATCCTGATACTCTTGATACTTTTGTAGATTCTTCTTGGTATTACTTGAGATACCCTGA CAATAAAAACGATAAAGAGCCTTTTAATAAAGAGTGGATAAACAAAATGCTTCCAGTAGATAAATATGTAGGTGGAGCAG AGCACGCCACTATGCACCTTTTGTATTCGAGGTTTATAACGAAAGTTTTAAGAGATCTGGGATACCTTAATTTTGATGAA CCTTTCCTTTCACTTGTGCATCAGGGGACGATTTTAGGGCCGGATGGCAGCAGAATGAGCAAATCAAGAGGGAATGTTAT TTCGCCGGATGACTATATTAAACAGTACGGTTCAGATGTATTTAGGCTGTATCTAATGTTTGGCTTCTCTTACTCAGAGG GCGGACCATGGAGCGATGAAGGAATAAAGGCTATTGCTAGATTTGTCAATAGGGTGGAGAGGTTTATAGAAAAATTTATT GAGACCAGACAAAATCCAGGGAAGACAAAAGAAGAAATGGAAGATGCGGAAAAAGAATTGAACTATGTGAGACATTACAC TATAAAACACGTGACATTGGATGCCGATAAATTTGAGTTCAACACTGCTATAGCGAGAATAATGGAACTTGTAAATGCTT TGTACAAATATGAAAATGAGGTTGAAGTAAAGAACATGAAATTTTATGAAGATGTGGTAAGAGATTTTGTAAAAATCCTG GCGCCCTTTGCGCCCCATTTCTCTGAAGAGATGTGGGAAAGACTGGGGTATGAATATTCTGTTTTCAATCAGAAGTGGCC TGAGTGGGACGAAAAAGCCCTTGAAAGAGACATGATAGAAATTGCTATTCAGGTAAACGGAAAGGTTAGAAGCAAGGCTC AAGTGCCTTCAAATGCGACGGATGAAGAGTTGAAGCAGATTGCTCTTTCTGATGAGAGAGTGAAATCTTACCTGGATGGC AAAGAAATAAAGAAAGTGATAATTGTAAAAAATAGACTTGTAAATATTGTGGTAAACTAA Protein sequence : MEDMAYSVEIDRKWQKIWEETKLYKFNPENVDKKLYCLEMFPYPSGAKLHIGHWYNYGPTDSWARMKRMQGYEVFHPMGF DAFGLPAENYAIKTGIHPYDSTMENIRTMERQLREMGVTFDWDYEIITCLPEYYKWTQWIFLKLYEAGLAYRKKAPVNWC PSCQTVLANEQVIDGKCERCGTEVTKKELTQWFFKITAYAEELLEKLDDLDWPEKTKMMQRNWIGKSEGAEIEFKIDGKD LSFRVFTTRADTLFGATYVVLAPEHELVDLITTEEYKEAVEEYKEYAKKQSEIERLSTEKEKTGVFTGAYAIHPLTGEKL PIWIADYVLVTYGTGCVMGVPGHDERDYEFATKYNLPIKRVIKGVGDVDDSLPFVEYGILVNSEEFTGMTSEEARVKIVE KLKAEGKAEFKVNYRMRDWLVSRQRYWGAPIPIIHCERCGIVPVPEEDLPVLLPYDVEFEPTGESPLKKHAGFMNVTCPK CGGPALRDPDTLDTFVDSSWYYLRYPDNKNDKEPFNKEWINKMLPVDKYVGGAEHATMHLLYSRFITKVLRDLGYLNFDE PFLSLVHQGTILGPDGSRMSKSRGNVISPDDYIKQYGSDVFRLYLMFGFSYSEGGPWSDEGIKAIARFVNRVERFIEKFI ETRQNPGKTKEEMEDAEKELNYVRHYTIKHVTLDADKFEFNTAIARIMELVNALYKYENEVEVKNMKFYEDVVRDFVKIL APFAPHFSEEMWERLGYEYSVFNQKWPEWDEKALERDMIEIAIQVNGKVRSKAQVPSNATDEELKQIALSDERVKSYLDG KEIKKVIIVKNRLVNIVVN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 2e-156 | 47 |
