Gene Information

Name : SerS (TTE0025)
Accession : NP_621737.1
Strain : Thermoanaerobacter tengcongensis MB4
Genome accession: NC_003869
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 28805 - 30082 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGCTTGACATAAAATTTATAAGGAGTAATCCAGATGTAGTCAGAAGGGCTATAGAATTAAAAGGAGAAAAAGCGGACTT
GGACAGGCTGCTTTTACTGGATGAAAAAAGAAGAGAGATGCTTGTGGAACTGGAGGCTCTTAAAAATAAGAGGAATACAG
AATCAGACAATATAGCTCGGCTAAAAAGAGAAGGGAAAGATGCGTCAGAACTTATCGCTAAAATGAAAGAACTTTCAGAT
AAGATAAAAGACATGGAACAGGAATTGAGGGAAATAGAAGAAGAAATGGAAAAGATACTCTGGACAATTCCCAATATTCC
TCATGAGAGTGTGCCTATAGGAGAAAGCGATGAGGACAACGTAGAGGTTAGAAGATGGGGAGAGCCCAGAAAGTTTGACT
TTGAACCTAAGCCCCATTGGGAAATAGGTGAGGCTTTGGGAATACTGGATTTTGAAGCGGCTTCTAGGGTTACAGGTTCT
CGTTTTGTATTTTACAAAGGGTTAGGAGCAAGGCTTGAGAGAGCTTTGATAAACTTTATGTTGGACCTTCACATAGAAAA
GCACGGCTATAAAGAAGTTTTTCCTCCATTCCTTGTACATAGGAGAAGCATGTTTGGGACAGGCCAGCTTCCAAAATTTG
AAGAAGATGCCTTCAAAGTAGAAGGCACAGACTATTTCCTGATTCCGACTGCAGAAGTTCCTGTGACTAACCTTTACAGA
GAGACTATAATAGACGGAGAACAGCTTCCTATATACCACTGCGCTTACAGTGCTTGTTTCAGGCAGGAAGCAGGGGCTGC
TGGAAGAGATACCAGAGGGCTTATAAGGCAGCATCAGTTCGACAAGGTAGAGCTGGTTAAATTCACAGAACCGGACAAAT
CTTACGAGGAATTGGAAAAAATGACAAGAGATGCAGAAGAAGTTCTGCAGGCTCTTGGCCTTCCTTACAGAGTGGTTGCT
ATATGCACAGGGGATTTAGGATTTACTGCATCAAAGAAATACGACATAGAAGTTTGGATGCCAAGTTATGGAAGATACGT
AGAGATATCTTCCTGCAGCAATTGTGAGGACTTCCAGGCCAGAAGAGCCAATATAAGGTATAGGCCAAAAGGTGGAGGAA
AACTCCAATATGTTCACACTTTAAATGGTTCTGGAGTGGCAGTTGGGAGGACTTTTGCGGCTATTCTAGAAAATTATCAG
CAGGAAGACGGATCTGTAGTTGTGCCTGAAGTATTGAGGCCATATATGAAAGTAGATGTTATAAGGAAGGAAGAATGA

Protein sequence :
MLDIKFIRSNPDVVRRAIELKGEKADLDRLLLLDEKRREMLVELEALKNKRNTESDNIARLKREGKDASELIAKMKELSD
KIKDMEQELREIEEEMEKILWTIPNIPHESVPIGESDEDNVEVRRWGEPRKFDFEPKPHWEIGEALGILDFEAASRVTGS
RFVFYKGLGARLERALINFMLDLHIEKHGYKEVFPPFLVHRRSMFGTGQLPKFEEDAFKVEGTDYFLIPTAEVPVTNLYR
ETIIDGEQLPIYHCAYSACFRQEAGAAGRDTRGLIRQHQFDKVELVKFTEPDKSYEELEKMTRDAEEVLQALGLPYRVVA
ICTGDLGFTASKKYDIEVWMPSYGRYVEISSCSNCEDFQARRANIRYRPKGGGKLQYVHTLNGSGVAVGRTFAAILENYQ
QEDGSVVVPEVLRPYMKVDVIRKEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-116 59