Gene Information

Name : PykF (TTE1815)
Accession : NP_623403.1
Strain : Thermoanaerobacter tengcongensis MB4
Genome accession: NC_003869
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1762883 - 1764634 bp
Length : 1752 bp
Strand : -
Note : Best Blastp hit = gi|10175785|dbj|BAB06882.1| (AP001517) pyruvate kinase [Bacillus halodurans], score 674, E-value 0

DNA sequence :
ATGAGGAGAACAAAAATAGTCTGTACAATTGGACCTGCTAGTGAGGACTACAATATACTGAGAAAGTTAATAGAAAAAGG
AATGAATGTAGCAAGGCTTAATTTTTCCCATGGAGATTTTGAAGAGCACGGAGCGAGGATTGACAACATAAAAAAGATAA
GGGAAGAATTAGGTCTTCCTGTAGCTATTTTGCTGGACACAAAAGGACCCGAGATTAGAACGGGAAAGTTTAAAAACGGC
GGAGTAGAGTTAAAGGAAGGCCAGACTTTTACATTAACTACAAGGGATGTAATAGGAGATGAAACGGTAGTCAGTGTTTC
CTACAAAGGTTTGCCTCAAGATGTTTCAAGAGGTACCCAAATTTTGATTGATGACGGATTGATCTCACTAAGGGTTGTGG
ATGTCAAAGGGGAAGACATAATCTGTGTAGTTGAAAATTCGGGATTTCTTGGAGACCACAAAGGAGTAAATGTTCCTGGA
GTGAAATTGAATCTCCCGGCTTTGACACAAAAAGACATAGAAGATATAGAGTTTGGCATAAAGAAAGGTATTGACATGAT
AGCTGCTTCTTTTGTCAGGAAAGCGGCAGATGTGCTTGCTATAAGGAGGCTTCTTGAGGACAATAAAGCAGACCACATTC
AGATAATTGCTAAAATAGAAAACCGCGAAGGAGTAGAAAATATAGACGAAATAATAAGGGTATCTGACGGGATAATGGTG
GCCAGAGGAGATTTGGGCGTTGAGATACCTCTGGAGGAAATACCGATAGTGCAGAAGATGATAATAAAGAAGTGCAATGA
AGCTGGAAAGCCAGTTATTACTGCAACCCAAATGCTGGATTCCATGATGAGAAATCCGCGTCCTACTCGTGCTGAAGTTA
CGGATGTTGCTAATGCTATTTTGGATGGAACGGATGCCATAATGCTGTCAGGTGAGACGGCCCAGGGCAAATATCCTGTC
GAAGCTTTTGAGACAATGGCCAGGATTGCGGAAAAGACAGAGGTTTACGTCCAGTACAGAGATATAGTAGGTGTAGGTAC
AGAGAGAAATGTTTCCATTACTAATGCGATAAGCCATGCTACCTGCACGACTGCGAGAGATATAGGCGCTTCAGCTATCA
TAACCTGTACAAAATCAGGTTATACGGCTAGGATGGTTTCAAGGTATAGGCCTTCCTCTCCTATCATAGCTACTACTCCT
AGCGAGCAGGTGGCAAGAAAGCTTTCCATCGTGTGGGGAGTATATCCTTTAGTGACAAAAGAAGTGTCAACCACAGACGA
AATGATAGATGTTGCAATAGAAAGTGCGTTAAAAGCTGGGCTTATAAGGAATGGAGATATTGTGGTGATTTCTGCGGGAA
TACCTGTTGCCATGACTGGCACCACAAACATGCTCAAAGTTCACATAGTTGGAGATGTGATTTTAAGAGGTATTGGTATA
GGTTCAAAATCTACTACTGGCACTGTGTGCATAATTCATGACATTGGCAAGGACAGAGACAAGTTTAGAGAAGGAGATAT
AATTGTTACAACCAAGACAGAGAGAGATTTTATGCCTCTTATTGAAAAAGCTTCTGCCATAATAACAGAAGAAGGCGGGC
TCACCTCCCACGCTGCTATTGTTGGGCTTAACTTGGGGATCCCTGTGATTGTAGGGTGTGAAGGAGCTACTTCAAAACTT
CAGGATGGGATGACAGTCACTGTTGACACCACGAGAGGACTGGTGTATAAAGGAATTGTAAACATAAAATGA

Protein sequence :
MRRTKIVCTIGPASEDYNILRKLIEKGMNVARLNFSHGDFEEHGARIDNIKKIREELGLPVAILLDTKGPEIRTGKFKNG
GVELKEGQTFTLTTRDVIGDETVVSVSYKGLPQDVSRGTQILIDDGLISLRVVDVKGEDIICVVENSGFLGDHKGVNVPG
VKLNLPALTQKDIEDIEFGIKKGIDMIAASFVRKAADVLAIRRLLEDNKADHIQIIAKIENREGVENIDEIIRVSDGIMV
ARGDLGVEIPLEEIPIVQKMIIKKCNEAGKPVITATQMLDSMMRNPRPTRAEVTDVANAILDGTDAIMLSGETAQGKYPV
EAFETMARIAEKTEVYVQYRDIVGVGTERNVSITNAISHATCTTARDIGASAIITCTKSGYTARMVSRYRPSSPIIATTP
SEQVARKLSIVWGVYPLVTKEVSTTDEMIDVAIESALKAGLIRNGDIVVISAGIPVAMTGTTNMLKVHIVGDVILRGIGI
GSKSTTGTVCIIHDIGKDRDKFREGDIIVTTKTERDFMPLIEKASAIITEEGGLTSHAAIVGLNLGIPVIVGCEGATSKL
QDGMTVTVDTTRGLVYKGIVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-108 52
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-108 52
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-108 52
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-108 52
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 4e-58 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PykF NP_623403.1 pyruvate kinase VFG0479 Protein 8e-109 52