Gene Information

Name : MetC2 (TTE1574)
Accession : NP_623174.1
Strain : Thermoanaerobacter tengcongensis MB4
Genome accession: NC_003869
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1531753 - 1532934 bp
Length : 1182 bp
Strand : +
Note : Best Blastp hit = gi|2500947|sp|P56069|METB_HELPY CYSTATHIONINE GAMMA-SYNTHASE (CGS) (O-SUCCINYLHOMOSERINE (THIOL)-LYASE) gi|7437084|pir||B64533 cystathionine gamma-synthase - Helicobacter pylori (strain 26695) gi|2313189|gb|AAD07176.1| (AE000532) cystath

DNA sequence :
GTGGAACTTCATTTCAAAACAAAAGTAGTTCATATTGGAAATTATGTGGATGAAAAAATTCCTCCAAAACCCAAAACTCT
CCCTATATATCAAACTTCTGTATTTACTTTTGATACTCTTGAAGAAGTTTATGATTACTTAGACGGCAATCCTTCAAGGT
ATATGTACACAAGGCTTGGAAACCCAAACCAAACTGCTGTAGAAGAATTAATTGCAAATTTAGAAGGAGCAGAGGCAGGG
CAAGCCTGTGCTTCAGGGATGGCAGCAATTTCCTCAGCTCTCCTGGCAGAAGTAAATTCAGGCGACCACATAATCGCAGC
AAAAGACATATACGGAGGAACAAACAGCCTTTTTAATTTGGAGTTTAAGAGATTGGGAATTGAAATAAGTTTGGTGGATT
TTTCGGACTTAGAATCTGTAGAAAAGGCTATCAAGCCAAATACAAAAGTCATATACATGGAAATCATGACAAATCCTTTG
ATAAGAGTATTTGACATTGAAGAAGTTGTAAAAATAGCAAAAAGGCACGGATTAAAACTTATAGTAGACAATACTTTTAC
AACTCCTTACCTGATAAGGCCTTTAGAAGTCGGCGCTTATGCTGTAATACATAGCGCCACAAAATACATAAACGGACACA
GTGATGTAATAGGAGGACTTATAGCAGGAAATAAAGAATTTATTTTCCGCACAAGGAGAATAGTCCACAATTTTGGAGGC
TCTATGAGTCCTTTTGACGCATGGCTCACTTTAAGAGGTGCTAAAACACTGTTTTTAAGGATGAGAGAGCACTGCAAAAA
CGCAATGCGATTGGCCGAATTTTTAGAAAGCCATCCAAAAGTGAAAAAGGTCTTCTATCCAGGACTGCCTTCTCACCCTG
ATTACAGCATCGCCAAAAAGCTTTTTAAGGATGAATTTGGAGGCATGTTGAGCTTTGAAATTGACGGTGGTGAACAATCT
GTAAATAGATTCATGCAGGAGCTCAAACTTATAAAATTTGCTCCATCACTGGCAGGAGTTCAAACCATGATAACACATCC
GAAGTCCACTTCCCACAGGGCTTTGAGCAAAGAAGAATTAAAAGCTCTTGGAATTTCAGAAGGACTCATAAGGGTGTCTG
TCGGAATTGAGGAAATAGAAGATGTGATAAGAGACTTTAAACAGGCTCTAGATAAAGTGTAA

Protein sequence :
MELHFKTKVVHIGNYVDEKIPPKPKTLPIYQTSVFTFDTLEEVYDYLDGNPSRYMYTRLGNPNQTAVEELIANLEGAEAG
QACASGMAAISSALLAEVNSGDHIIAAKDIYGGTNSLFNLEFKRLGIEISLVDFSDLESVEKAIKPNTKVIYMEIMTNPL
IRVFDIEEVVKIAKRHGLKLIVDNTFTTPYLIRPLEVGAYAVIHSATKYINGHSDVIGGLIAGNKEFIFRTRRIVHNFGG
SMSPFDAWLTLRGAKTLFLRMREHCKNAMRLAEFLESHPKVKKVFYPGLPSHPDYSIAKKLFKDEFGGMLSFEIDGGEQS
VNRFMQELKLIKFAPSLAGVQTMITHPKSTSHRALSKEELKALGISEGLIRVSVGIEEIEDVIRDFKQALDKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-58 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MetC2 NP_623174.1 cystathionine beta-lyase BAC0207 Protein 5e-68 43