Gene Information

Name : FliI (TTE1439)
Accession : NP_623057.1
Strain : Thermoanaerobacter tengcongensis MB4
Genome accession: NC_003869
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis/type III secretory pathway ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 1414229 - 1415542 bp
Length : 1314 bp
Strand : -
Note : Best Blastp hit = gi|10175075|dbj|BAB06174.1| (AP001515) flagellar-specific ATP synthase [Bacillus halodurans], score 529, E-value 1.00E-149

DNA sequence :
ATGAGTAGCGGGGTTTTGGAAAAATATTCAAAGATTTTGAGAGAAAAAAGGCTAGTAGGATATTACGGAAAAGTATCCCA
GGTGATAGGCCTTACTATTGAGAGCGTAGGTCCACTTTCTAATATAGGTGAAATATGCTACATAAAGACAATTGATGGGA
ATGAAGTTCTCGCTGAGGTAGTAGGTTTTAAGGAGGAAAAAGTCTATCTCATGCCTCTAGGCAACATGGAGGGAATTGGA
CCGGGAAGCAAAGTTATAGCTACAGGCCAGACCTTGAAAGTAAATGTAGGGAAATCCCTTTTAGGGAGGGTTTTGGACGG
ACTTGGCAACCCAATAGATGGTAAAGGTCCCTTGAAATACGAAAAATCAATTCCTGTAAACAACACTCCTCCAGACCCTC
TGGAAAGAAAACGGATAAGAGAGGTAATGCCTCTAGGCATAAAGGCAATAGATGGTCTGTTGACTTGCGGCAAAGGGCAG
AGGATTGGAATTTTTGCAGGAAGCGGAGTTGGGAAAAGTACCCTTCTCGGGATGATGGCGAGGAACGCAAAAGCAGATTT
AAACGTGATTGCTCTCATTGGAGAAAGAGGAAGAGAGGTAAACGAGTTTATAGAGAAAGACCTCGGAGAGGAAGGGCTAA
AGAGGTCTGTCGTGGTAGTAGCAACGTCTGATACGCCAGCTTTGGTGAGAGTGAAAGGAGCGATGACCGCTACTGCTATA
GCTGAGTACTTTAGAGACCAGGGCCTTGACGTGCTTCTCATGATGGACTCTATAACGCGCTTCGCGATGGCTCAGAGAGA
GATAGGTTTATCTATTGGAGAAGCACCTGTATCAAGGGGATACACTCCTTCTGTGTTTTCTGTGCTTCCAAAACTCTTGG
AGAGGTCAGGGTCATCTCAAAAGGGATCAATAACAGCTTTGTACACGGTTTTGGTAGACGGAGATGACCTTAATGAACCT
ATAGCTGACGCGGTAAGAGGCATACTGGATGGACACATAGTTTTATCCAGAAAGCTTGCAAACAAAAACCACTATCCGGC
CATAGACGTACTGGCAAGCGTGAGCAGGGTGATAAATGACATCATAACGGATGAACACAAGGAGCTGGTGGCAAAGTTTA
AGAATATCCTCGCCACTTACGCAGAAGCGGAGGACCTGATAAACATAGGAGCTTATAACTTTGGCACTAACCCTAAAATT
GACGAAGCGATTGAGCTTAATGAAAAAATGAACAGCTTCTTAAGGCAGAAAATCGATGAAGCTTATGATTTTGAAACTAC
GAAAAAACTTCTAGCTAAATCTCTTGAAAGGTGA

Protein sequence :
MSSGVLEKYSKILREKRLVGYYGKVSQVIGLTIESVGPLSNIGEICYIKTIDGNEVLAEVVGFKEEKVYLMPLGNMEGIG
PGSKVIATGQTLKVNVGKSLLGRVLDGLGNPIDGKGPLKYEKSIPVNNTPPDPLERKRIREVMPLGIKAIDGLLTCGKGQ
RIGIFAGSGVGKSTLLGMMARNAKADLNVIALIGERGREVNEFIEKDLGEEGLKRSVVVVATSDTPALVRVKGAMTATAI
AEYFRDQGLDVLLMMDSITRFAMAQREIGLSIGEAPVSRGYTPSVFSVLPKLLERSGSSQKGSITALYTVLVDGDDLNEP
IADAVRGILDGHIVLSRKLANKNHYPAIDVLASVSRVINDIITDEHKELVAKFKNILATYAEAEDLINIGAYNFGTNPKI
DEAIELNEKMNSFLRQKIDEAYDFETTKKLLAKSLER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 4e-109 57
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-106 53
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-106 53
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-105 53
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-105 53
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-105 53
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-105 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-105 52
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-102 51
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-102 51
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-90 51
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-90 51
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-91 51
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-91 51
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-91 51
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-89 51
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-89 51
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 8e-96 51
escN AAC31513.1 L0034 Virulence LEE Protein 9e-94 50
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 9e-94 50
escN AAC38383.1 EscN Virulence LEE Protein 8e-94 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-93 50
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-93 50
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-94 50
escN CAI43874.1 EscN protein Virulence LEE Protein 8e-94 50
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-93 50
escN AAL57542.1 EscN Virulence LEE Protein 2e-93 49
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-93 49
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-93 49
escN AAK26715.1 EscN Virulence LEE Protein 2e-93 49
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-91 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 7e-80 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-81 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-79 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-83 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-83 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 7e-92 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-83 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 7e-88 46
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 8e-83 46
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-83 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-78 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-78 45
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-74 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-77 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-73 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-73 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-73 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-73 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-71 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2144 Protein 6e-114 56
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0192 Protein 3e-110 56
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0048 Protein 1e-110 56
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0390 Protein 5e-109 55
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0515 Protein 6e-91 51
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG1254 Protein 9e-105 51
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0812 Protein 5e-94 50
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0730 Protein 5e-94 50
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2499 Protein 9e-98 50
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2331 Protein 2e-94 48
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG1008 Protein 8e-75 44
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG1778 Protein 2e-75 44
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG2459 Protein 3e-82 43
FliI NP_623057.1 flagellar biosynthesis/type III secretory pathway ATPase VFG0555 Protein 9e-74 42