Gene Information

Name : serS (MA4048)
Accession : NP_618916.1
Strain : Methanosarcina acetivorans C2A
Genome accession: NC_003552
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 4966172 - 4967437 bp
Length : 1266 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGGAACTCAAATTTGTACGAAATAACCCCGACATAGTTGGGCGTGCCCTTGTTAACAGAAATATGGGCACAGAGCT
TATAGATAGCCTTCTTGAGTATGACGTGGCCTGGAGGAAATGCCTCACCGAAGGCGACAGCCTCAAGCATAAACGCAACG
TGGTCACCCGCGAGATAGCGCAGCTTAAGAAGGAAAATAAGGACACCTTATCCAAGATAAATGAGATGCAGGACATAAAC
AACCGTATTAAAGAAATCGATGATAAAATACGTGACTATAAGTCAAAAATAAATGAGATAATGCTCAGCATCCCTAATAT
CCCCTCCGAGACAACGCCTGTAGGCAAAGATGAAAATGACAATCCTGTTGTAAGGGTAGTTGGAGAGAAGAAGAAATTTA
CTTTTACTCCAAAGCCTCACTGGGAAATCGGAGAGGCGCTGGATATACTCGACTTTGAACGAGGAGCAAAGATAGCAGGG
CAGGGCTTTACGGTCTATAAAGGGCTTGGTGCAAAGCTTGAAAGAGCCCTCATAAACTTCATGCTTGATGTACACACCAG
GCAGGGGTATCTCGAAGTTTTCCCGCCTGTGCTAATCAATGAAAAAGCCATGACCGGCACAGGGCAGCTGCCAAAGTTCA
AGGAAGATATGTACTTGTGCTGCGCTGACGGCTATTATCTTGCCCCGACTGCAGAAGTCCCGGTGACCAACCTCTTCATG
GACGAGTATATGGAGAACCTACCGGTATCCCTTACAGCATATACCGCCTGCTTCAGGCGGGAAGCAGGAAAACACGGGCA
GGATACAAGAGGCATCATTCGACAGCACCAGTTCAACAAGGTTGAACTTGTCAAGTTCGTAAAACCTGAAACCTCCTATG
AAGAACTGGAAAAACTCACCCTCGATGCCGAAGAGATTCTAAAACTTCTCAAGCTACCCTATCGCTTAGTAACCCTTTGC
ACTGGCGACCTGGGCTTTTCGGCTGCCAAGACCTACGACATTGAGGTATGGGTCCCCACACAGGAAAAGTACCGGGAGAT
CTCCTCGTGCTCGAATTTCGAAAACTTCCAGGCAAGGAGAGCAAATATCCGCTTCAGGACCCCTGAAGGTCCGCAGTTTG
TCCACACGCTTAACGGCTCAGGCCTGGCTGTAGGCAGGACCGTCGTTGCTATCCTTGAGAACTACCAGCGTGAGGACGGC
AGTGTGGAGATTCCGGAAGTTCTCAGGCCTTACATGGGCGGGGTCGAAGAAATCAGAGAAGAGTGA

Protein sequence :
MLELKFVRNNPDIVGRALVNRNMGTELIDSLLEYDVAWRKCLTEGDSLKHKRNVVTREIAQLKKENKDTLSKINEMQDIN
NRIKEIDDKIRDYKSKINEIMLSIPNIPSETTPVGKDENDNPVVRVVGEKKKFTFTPKPHWEIGEALDILDFERGAKIAG
QGFTVYKGLGAKLERALINFMLDVHTRQGYLEVFPPVLINEKAMTGTGQLPKFKEDMYLCCADGYYLAPTAEVPVTNLFM
DEYMENLPVSLTAYTACFRREAGKHGQDTRGIIRQHQFNKVELVKFVKPETSYEELEKLTLDAEEILKLLKLPYRLVTLC
TGDLGFSAAKTYDIEVWVPTQEKYREISSCSNFENFQARRANIRFRTPEGPQFVHTLNGSGLAVGRTVVAILENYQREDG
SVEIPEVLRPYMGGVEEIREE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-110 54