Gene Information

Name : mgl (MA2532)
Accession : NP_617435.1
Strain : Methanosarcina acetivorans C2A
Genome accession: NC_003552
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 3147930 - 3149150 bp
Length : 1221 bp
Strand : -
Note : -

DNA sequence :
ATGGAAAGAGAACTTAAGTTTGCAACCAAATGTGTGCATGCAGGAGAAGAGCCGGACCCTGTCTTCGGGGCGCATACGAC
TCCGATATTTCAGACTTCAACTTTCATTTTTAAGAATGTCGAACAGGGGGCTGCCAGGTTTGCAGGAGAGGAATCAGGGT
ACGTATACACAAGAATCCCTCCGAACACACCTACACATGCGGTCCTTGCCGAAAAGGTTGCTGTACTTGAGGGCGGGGAG
GCAGGACAGACCTTTGCTTCCGGAATGGCTGCAATAACCGCAGTTGTACTCTCAACCCTGAAACAGGGAGACCACCTGAT
CTCAACGGATGTGGTGTACGGCTGCACCTACAGCCTCTTTTCGGAGATCCTGCCCGGGTTTGGGATAGATGTCAGTTTTG
TTGATACATCCGATATAAAAAAGGTGAGAGCAGCCTTTAAGCCGGAAACCAGAATGGTTTTTCTGGAAACGCCTGCCAAT
CCCACAATAACGGTCTGCGACATCAGGGAGATTTCCAAACTTGCAAAGGCACAGGGGGCCATTTGCATCGTGGATAATAC
CTTTGCAACGCCGTATTTCCAGAAACCCCTTGAACTCGGGGCAGACATATCCCTAAGCAGCTGCACAAAATACATAGGCG
GGCACGCTGACCTTCTCGGTGGAATCGTTGTAGGGAGCAGGGATTTTATGAAAAGCCTGGGAAAGGTTGTTGGGTATACC
GGAGGGATCATGGGACTGCACGAAGCCTGGCTCTGTATCAGGGGGCTTAAGACTCTGCACATCCGGATGGAAAGGCATGC
TGAAAACGCCCTGACGGTTGCAAACTTCCTTGAGGCTCATCCCACAGTAGAATGGGTCAGGTATCCCGGACTTTCAAACC
ATCCTCAGCACGAGGTCGCAAAAAAACAGATGAGCGGCTATGGTGGAATGCTCTCTTTCGAGATCAGGGGAGGAGTTGAA
GCCGGGCGCAGGCTTATGGACAGCGTCAGGCTCTGCTCTCTTGCAGTGAGCCTGGGGGCAACTGATACCCTTATCCAACA
CCCCGCTTCCATGACCCATGCCTGCATTCCCGGGCATATAAGAAACAAGGTCGGAATCAAAGACGGACTTGTCAGGCTGT
CTGTTGGAATCGAAGACCCTGAAGATATAATTGCAGACCTTGAACAGGCCCTCTCAAAAGTTTATTGCCGGAGAGGAAAC
GGATTCGACCCATGTAATTGA

Protein sequence :
MERELKFATKCVHAGEEPDPVFGAHTTPIFQTSTFIFKNVEQGAARFAGEESGYVYTRIPPNTPTHAVLAEKVAVLEGGE
AGQTFASGMAAITAVVLSTLKQGDHLISTDVVYGCTYSLFSEILPGFGIDVSFVDTSDIKKVRAAFKPETRMVFLETPAN
PTITVCDIREISKLAKAQGAICIVDNTFATPYFQKPLELGADISLSSCTKYIGGHADLLGGIVVGSRDFMKSLGKVVGYT
GGIMGLHEAWLCIRGLKTLHIRMERHAENALTVANFLEAHPTVEWVRYPGLSNHPQHEVAKKQMSGYGGMLSFEIRGGVE
AGRRLMDSVRLCSLAVSLGATDTLIQHPASMTHACIPGHIRNKVGIKDGLVRLSVGIEDPEDIIADLEQALSKVYCRRGN
GFDPCN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-75 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-76 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 9e-66 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mgl NP_617435.1 methionine gamma-lyase BAC0207 Protein 2e-84 47