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Name : nrdF (spyM18_0470) Accession : NP_606699.1 Strain : Streptococcus pyogenes MGAS8232 Genome accession: NC_003485 Putative virulence/resistance : Unknown Product : ribonucleotide-diphosphate reductase subunit beta Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0208 EC number : 1.17.4.1 Position : 385440 - 386453 bp Length : 1014 bp Strand : + Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE DNA sequence : ATGACCCAACATTATTATGAACGTTCGCAATCCCCAATTGAATACGCCCTATCTGAAACACAAAAACAGTTGCGCTCCAT CAATTGGAATTACCTTAATGATGACAAAGATTTGGAAGTGTGGAACCGTGTCACTCAAAATTTTTGGTTGCCTGAAAAGG TTCCTGTTTCTAATGATTTAAATTCTTGGCGCTCCTTGGGTGAGGATTGGCAACAGCTCATCACAAGGACCTACACTGGG TTGACTTTACTAGATACAGTACAAGCAACGGTTGGTGATGTGGCACAAATTCAGCATTCACAAACCGACCACGAACAAGT CATCTATACGAACTTTGCCTTTATGGTGGGGATCCATGCCCGCTCTTACGGGACGATTTTTTCGACCCTTTGCAGTAGCG AGCAAATCGAAGAAGCACATGAATGGGTGGTCTCAACACAGAGCTTGCAAGACCGTTCCCGTGTCTTGATTCCTTACTAT ACGGGTGATGACCCTTTGAAATCAAAAGTAGCAGCAGCTATGATGCCAGGATTTTTGCTGTATGGCGGCTTTTACCTTCC TTTTTACCTATCAGCACGTGGTAAAATGCCAAACACATCTGATATCATCCGCCTGATTTTACGCGACAAAGTTATTCACA ACTATTACAGCGGTTACAAATACCAACAAAAAGTAGCACGTCTTAGCCCAGAAAAACAGGCTGAAATGAAGGCCTTTGTC TTTGACTTGCTCTATGAACTCATCGACCTTGAAAAAGCTTACTTGAGAGAACTGTATGCAGGCTTTGATTTGGCAGAAGA TGCTATCCGCTTTAGCCTTTATAACGCTGGAAAATTCCTTCAAAATTTAGGCTATGATTCGCCCTTCACAGAAGAAGAGA CCCGTATCTCACCTGAAGTATTTGCTCAGCTATCAGCGCGTGCAGACGAAAACCATGACTTTTTCTCAGGCAATGGCTCA TCTTATGTGATGGGGATCACCGAAGAAACCACAGATGACGATTGGGAGTTTTAA Protein sequence : MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRVTQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTG LTLLDTVQATVGDVAQIQHSQTDHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRSRVLIPYY TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSGYKYQQKVARLSPEKQAEMKAFV FDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNAGKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGS SYVMGITEETTDDDWEF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cur_1479 | YP_001800873.1 | ribonucleoside-diphosphate reductase subunit beta | Not tested | Not named | Protein | 1e-71 | 52 |
