Gene Information

Name : hasC2 (spyM18_0210)
Accession : NP_606501.1
Strain : Streptococcus pyogenes MGAS8232
Genome accession: NC_003485
Putative virulence/resistance : Virulence
Product : UDP-glucose pyrophosphorylase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1210
EC number : -
Position : 190425 - 191324 bp
Length : 900 bp
Strand : -
Note : best blastp match sp|P58098|HAC2_STRPY UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE 2 (UDP-GLUCOSE PYROPHOSPHORYLASE 2) (UDPGP 2) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE 2) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE 2)

DNA sequence : 
ATGACCAAAGTCAGAAAAGCTATTATTCCCGCAGCAGGTTTAGGCACACGTTTTTTACCTGCAACCAAGGCCCTTGCCAA
GGAGATGCTACCTATTGTTGATAAACCAACTATTCAATTTATCGTTGAAGAAGCTCTAAAATCAGGTATCGAAGAAATTC
TTATCGTTACTGGAAAATCCAAACGCTCCATAGAAGATCATTTTGATTCTAATTTTGAATTAGAATATAATTTACAGGCT
AAAGGAAAAATCGAACTTCTAAAGTTAGTAGACGAGACCACTTCTATTAACCTTCACTTTATTCGACAGAGTCATCCAAG
AGGATTAGGAGACGCAGTTCTTCAAGCAAAGACCTTTGTTGGCAATGAACCTTTTGTTGTCATGCTAGGTGATGATCTGA
TGGATATTACAAATCCAAATGTAAAACCATTAACCAAACAATTGATCGATGACTATGAAGAAACTCATGCTGCAACTATT
GCCGTCATGAGAGTTCCTCACGAGGATGTCTCTAACTACGGTATCATTGCTCCTCAAGCAAAAGCAGTAAAAGGACTCTA
TAGTGTGGATACTTTTGTTGAAAAACCACAACCTCAAGATGCACCTAGTGATTTGGCAATTATTGGACGTTACTTGCTCA
CACCAGAAATTTTTAGTATTTTAGAAAAACAAGAACCTGGTGCAGGCAATGAAGTTCAACTGACTGATGCTATTGATACC
CTCAATAAGACACAGCGTGTCTTTGCTCGTGAGTTTAAAGGGAAACGCTATGATGTTGGCGATAAATTTGGGTTTATGAA
AACTTCTTTGGATTATGCCCTGAAACACCCTCAAGTCAAAGATGACTTGAAAGCCTACATCATCCAACTGGGCAAAGCAC
TAGAGAAAACAAAACCATAA

Protein sequence : 
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQA
KGKIELLKLVDETTSINLHFIRQSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIFSILEKQEPGAGNEVQLTDAIDT
LNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKHPQVKDDLKAYIIQLGKALEKTKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0059 YP_300149.1 UTP-glucose-1-phosphate uridylyltransferase Not tested SCC15305cap Protein 2e-74 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hasC2 NP_606501.1 UDP-glucose pyrophosphorylase VFG0964 Protein 2e-133 91