Gene Information

Name : ulaA (spyM18_2016)
Accession : NP_607997.1
Strain : Streptococcus pyogenes MGAS8232
Genome accession: NC_003485
Putative virulence/resistance : Virulence
Product : PTS system ascorbate-specific transporter subunit IIC
Function : -
COG functional category : S : Function unknown
COG ID : COG3037
EC number : -
Position : 1677405 - 1678784 bp
Length : 1380 bp
Strand : -
Note : membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr

DNA sequence :
ATGGAAGCATTATTATCATTTATTCGAGATATTTTAAAAGAACCTGCATTTTTAATGGGCTTGATTGCCTTTGCAGGGTT
GGTGGCTTTGAAAACACCTGCTCATAAGGTGTTGACAGGAACCTTGGGGCCGATTTTGGGATACCTTATGCTTGCTGCAG
GGGCGGGTGTTATTGTGACCAATCTGGACCCTCTTGCCAAACTCATTGAGCACGGTTTTAGCATCACTGGCGTAGTGCCA
AATAATGAAGCCGTCACTTCTGTCGCTCAAAAGATTCTGGGTGTGGAAACTATGTCCATCTTGGTGGTTGGGTTATTGCT
CAATTTGGCTTTTGCTCGTTTTACCCGCTTCAAATACATTTTCTTAACAGGACATCACAGCTTCTTTATGGCTTGTCTCT
TGTCCGCCGTGCTTGGAGCTGTTGGTTTCAAAGGAAGTCTTTTGATTATCTTAGGTGGGTTCCTCTTGGGAGCTTGGTCA
GCTATTTCGCCAGCCATTGGTCAACAGTATACTCTGAAAGTGACTGACGGAGATGAAATCGCCATGGGACACTTTGGTAG
TTTGGGCTATTACCTTTCTGCCTGGGTTGGTAGCAAGGTTGGCAAAGACAGTAAAGATACCGAGGACCTTCAGATTTCTG
AAAAATGGAGTTTCTTACGCAACACCACCATTTCAACAGGACTTATCATGGTGATTTTCTACTTGGTGGCAACAGTGGCT
TCTGTTTTGAGGAATGCTTCAGTAACAGAAGAATTAGCAGCAGGTCAAAACCCATTTATCTTTGCTATTAAGAGTGGTCT
TACCTTTGCGGTTGGTGTGGCAATTGTCTACGCCGGTGTTCGCATGATTTTGGCTGACTTGATTCCAGCCTTCCAAGGTA
TTGCTAACAAATTAATTCCAAATGCTATTCCAGCTGTAGACTGTGCGGTATTCTTCCCTTATGCGCCAACCGCTGTTATC
ATCGGTTTTGCGTCAAGTTTCGTTGGTGGCTTACTTGGGATGTTGATTTTAGGAGTTGCAGGTGGTGTCCTGATTATCCC
AGGTATGGTGCCTCATTTCTTCTGTGGTGCAACAGCAGGGATTTTTGGAAATTCAACAGGTGGTCGTCGCGGTGCGATGA
TTGGTGCTTTCGCTAATGGCTTATTACTCGCCTTCTTGCCAGCCATGCTTCTACCTGTACTTGGTAAACTTGGTTTTTCA
AACACGACCTTTGGAGATGTGGATTTCGGTGTTTTAGGGATTTTACTGGGCCGCTTAGGAACGTCGATTGGTCAAATCGG
TATTTACTTGGTGGTTGCTGTGCTTGCTATTGTATTGGTGCTTCCAAACTTTCTGTCAAAATCTCAAGAGGCCATCAATA
ATGTTTCAGAAGAAATCTAA

Protein sequence :
MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGPILGYLMLAAGAGVIVTNLDPLAKLIEHGFSITGVVP
NNEAVTSVAQKILGVETMSILVVGLLLNLAFARFTRFKYIFLTGHHSFFMACLLSAVLGAVGFKGSLLIILGGFLLGAWS
AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVGSKVGKDSKDTEDLQISEKWSFLRNTTISTGLIMVIFYLVATVA
SVLRNASVTEELAAGQNPFIFAIKSGLTFAVGVAIVYAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVI
IGFASSFVGGLLGMLILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLPVLGKLGFS
NTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLAIVLVLPNFLSKSQEAINNVSEEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAC39291.1 hypothetical protein Not tested LPA Protein 3e-75 50
vpeC ADD91725.1 putative PTS system-specific IIC component VpeC Virulence PAI-I AL862 Protein 3e-75 50
ORF8 AAK27335.1 unknown Not tested PAI-I AL862 Protein 2e-75 50