Gene Information

Name : spyM18_1849 (spyM18_1849)
Accession : NP_607863.1
Strain : Streptococcus pyogenes MGAS8232
Genome accession: NC_003485
Putative virulence/resistance : Unknown
Product : aminotransferase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 1524862 - 1526076 bp
Length : 1215 bp
Strand : -
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGAAAATTATTGAAAAATCATCAAAATTAGAACATGTTGCCTATGATATTCGAGGGCCTGTTTTGGATGAAGCTAATCG
CATGATTGCGAGTGGTGAAAAAATTCTGCGTTTAAATACTGGCAATCCTGCTGCCTTTGGTTTTGAAGCACCAGATGAAG
TGATTCGTGATTTAATTGTCAACGCGAGGCTAAGTGAGGGCTATTCTGACAGTAAAGGGATTTTTTCAGCGCGTAAGGCT
ATCATGCAGTATTGCCAACTCAAGGGCTTCCCAGATGTTGACATTGAAGATATTTATTTGGGAAATGGCGTGTCAGAGTT
GATATCCATGTCCCTTCAAGCTTTGCTAGATAATGGCGATGAAGTTTTAGTACCAATGCCGGATTATCCTTTATGGACGG
CTTGTGTGAGTCTTGGTGGAGGAAAAGCAGTCCATTATCTTTGTGATGAAGAAGCTGGTTGGTATCCTGATATTGCTGAT
ATCAAATCAAAAATCACGAGTCGCACCAAAGCTATTGTGGTCATCAATCCTAATAACCCAACAGGAGCCCTTTATCTTAA
GGAGATTTTAGAAGACATCGTTGCTTTGGCAAGAGAACACCAGCTGATTATTTTTGCCGATGAAATCTATGATCGTTTGG
TGATGGATGGTAAAGAGCATATTGCTATTGCAAGTTTGGCACCTGATGTTTTTTGTGTATCTATGAATGGCCTTTCCAAA
TCTCATCGTATTGCTGGTTTTCGTGTTGGATGGATGGTCTTATCAGGTCCTAAAGACCATGTTAAAGGTTACATTGAAGG
GTTGAACATGCTTGCCAATATGCGGTTATGCTCCAATGTTTTAGCTCAACAAGTTGTTCAAACTTCCTTAGGAGGCCATC
AATCAGTTGATGCACTGTTACTGCCAGGAGGGCGTATTTTTGAGCAACGTAATTTTATTTATGAAGCTATTAATGCTATC
CCTGGCTTATCGGCAGTTAAACCTGAAGCAGGTCTTTATTTATTTCCGAAAATTGATCGTCAGATGTATCGTATTGATGA
TGATGAAGAATTTGTCTTACAGTTATTAAAGCAAGAAAAAGTGATGTTGGTACATGGACGTGGTTTTAACTGGAAAGATC
CAGATCACTTCCGTATTGTTTACCTACCAAGTGTAGAAGAATTAGAAGATGTTCAAGAAAAGATTACACGTGTCTTATAC
CAGTATAGACGTTAA

Protein sequence :
MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPAAFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKA
IMQYCQLKGFPDVDIEDIYLGNGVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
IKSKITSRTKAIVVINPNNPTGALYLKEILEDIVALAREHQLIIFADEIYDRLVMDGKEHIAIASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRLCSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAI
PGLSAVKPEAGLYLFPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQEKITRVLY
QYRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 6e-117 57
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 6e-117 57
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 6e-117 57
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 6e-117 57