Gene Information

Name : spyM18_1238 (spyM18_1238)
Accession : NP_607349.1
Strain : Streptococcus pyogenes MGAS8232
Genome accession: NC_003485
Putative virulence/resistance : Virulence
Product : exotoxin SpeL
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0396
EC number : -
Position : 1041616 - 1042404 bp
Length : 789 bp
Strand : -
Note : best blastp match gb|AAB59091.1| (M97156) pyrogenic exotoxin C [Streptococcus pyogenes]

DNA sequence : 
ATGAGAATTTTTTTACACCAGAATTGTCGTTTGGTTAATATGTCAACTACTTTTTTTATAGTAGTATTGTCATTGATGGT
ATTTTCTGTTAGGATGGTTTCTGCGGAAGAGACTATTAATATTAAGGATATATACTCTCCAAGGTGGGATGTAGATAAAA
CATTATCCCCTACTACCTTAAGAGAAATTTATAATAGAGATACTATAAAAAAAGTGAATAAACCCATTACTGGAAAAAGA
GGGACGCAAGTTATTATGGATGCTCAGCATAAAACTAAAGTATGGGAATTTGATGATTATAATTTTATAATATCAAGTAA
CCTACACCCATCTGTAGAAGGTAAATTTAATGTTGGAGATAATGTCGATGTTTTTGGTCTTGCATTATCAGCTGAAGTAT
TTTCAAAAGATCAAATACATTCAATCAATGGTGGTCTCGTTAAAGTTAATGAGAGAAAAGGAGCCGGAAAAACGATTTAC
ATGAACGTTTTTATTGATGGGCATAAAAAAGATGATACCTCGAAATATAAAATAACTTTTGAAAAATCTCCCGTTACCTT
CCAGGAAGTTGATGTTAGATTGAGAAAATCATTTATGCTGAACGATGAAATAAAACTTTATCAGTATGATTCCAAAGTTC
TATCTGGAAACTGGGAATTTCACGGCTCAGGCGAGAAAGAGGAAGGTGCTGACTTATTTAAATACCCAGATTATAGATAT
AATAATTTGATAGATATAGACAAAAAGAGTCATATTGATGTCTATTTATTCACAAACAAAGAAAATTAA

Protein sequence : 
MRIFLHQNCRLVNMSTTFFIVVLSLMVFSVRMVSAEETINIKDIYSPRWDVDKTLSPTTLREIYNRDTIKKVNKPITGKR
GTQVIMDAQHKTKVWEFDDYNFIISSNLHPSVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIY
MNVFIDGHKKDDTSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYDSKVLSGNWEFHGSGEKEEGADLFKYPDYRY
NNLIDIDKKSHIDVYLFTNKEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
seeM YP_002746963.1 exotoxin M precursor Virulence ¥ÕSeq3 Protein 2e-110 97
seeL YP_002746964.1 exotoxin L precursor Virulence ¥ÕSeq3 Protein 3e-41 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spyM18_1238 NP_607349.1 exotoxin SpeL VFG0957 Protein 6e-121 100
spyM18_1238 NP_607349.1 exotoxin SpeL VFG0958 Protein 2e-37 44
spyM18_1238 NP_607349.1 exotoxin SpeL VFG0953 Protein 8e-41 42