Gene Information

Name : FN0110 (FN0110)
Accession : NP_603020.2
Strain : Fusobacterium nucleatum ATCC 25586
Genome accession: NC_003454
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 744883 - 746148 bp
Length : 1266 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTAGAATTAAAATTTATGCGTGAAAATGTTGAAATGCTTAAAGAAATGCTAAAAAACAGAAATAGCAATGTTGATAT
GGATGCTTTTGTTGAATTAGATTCAAAGAGAAGAGAAGTTTTATCCGAAGTAGAAAATTTAAAAAGAGAAAGAAATAATG
CTTCTGCAGAAATTGCAAATTTAAAGAAAGAAAAGAAAAATGCTGACCATATAATAGAAAAAATGGGAGAAGTTTCTACA
AAAATAAAAGATTTAGATGCTGAACTTGTTGAAATAGATGAAAAAATTAAAGATATTCAATTAAATATACCTAATGTATA
TCATCCATCAACTCCTATTGGTCCTGATGAAGATTATAACCTTGAAATCAGAAAATGGGGAATACCTAAGAAATTTGATT
TTGAACCAAAATCACACTGGGATATTGGAGAAGATTTAGGAATATTAGATTTTGAAAGAGGAGCAAAATTAAGTGGTTCA
AGATTTGTTCTATATAGAGGAGCAGCTGCAAGATTAGAAAGAGCTATAATTAACTTTATGCTTGATGTTCATACTTTGGA
AGAAGGTTACACAGAACATATAACTCCATTTATGGTTAAAGCAGAAGTTTGTGAAGGAACAGGGCAACTTCCAAAATTTG
AAGAAGATATGTATAAAACAACTGATGATATGTACTTAATTTCTACTTCTGAAATTACTATGACAAATATCCATAGAAAA
GAAATTTTAGAACAAGCTGAATTACCTAAATATTACACTGCTTATTCTCCTTGTTTCAGAAGAGAAGCAGGTTCTTATGG
AAAAGATGTCAAAGGTTTAATAAGATTACACCAATTTAATAAGGTAGAAATGGTTAAAATAACAGATGCTGAATCTTCTT
ATGATGAACTTGAAAAAATGGTAAACAATGCTGAAACAATCTTACAAAGATTAGAATTACCTTATCGTGTAATTCAACTT
TGTTCTGGAGATTTAGGTTTTAGTGCTGCTAAAACTTATGACTTAGAAGTTTGGTTACCATCTCAAAATAAATATAGAGA
AATTTCTTCTTGTTCAAACTGTGAAGCATTTCAAGCTAGAAGAATGGGATTAAAATATAGAGTTCCTAATGGAAGTGAAT
TCTGTCATACTTTAAATGGTTCAGGACTTGCAGTAGGTAGAACATTGGTTGCTATTATGGAAAATTATCAACAAGAAGAT
GGTTCTTTCTTAGTTCCTAAGGTATTAATTCCTTATATGGGTGGAGTAGATGTTATTAAAAAGTAG

Protein sequence :
MLELKFMRENVEMLKEMLKNRNSNVDMDAFVELDSKRREVLSEVENLKRERNNASAEIANLKKEKKNADHIIEKMGEVST
KIKDLDAELVEIDEKIKDIQLNIPNVYHPSTPIGPDEDYNLEIRKWGIPKKFDFEPKSHWDIGEDLGILDFERGAKLSGS
RFVLYRGAAARLERAIINFMLDVHTLEEGYTEHITPFMVKAEVCEGTGQLPKFEEDMYKTTDDMYLISTSEITMTNIHRK
EILEQAELPKYYTAYSPCFRREAGSYGKDVKGLIRLHQFNKVEMVKITDAESSYDELEKMVNNAETILQRLELPYRVIQL
CSGDLGFSAAKTYDLEVWLPSQNKYREISSCSNCEAFQARRMGLKYRVPNGSEFCHTLNGSGLAVGRTLVAIMENYQQED
GSFLVPKVLIPYMGGVDVIKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-118 58