Gene Information

Name : FN1941 (FN1941)
Accession : NP_602741.1
Strain : Fusobacterium nucleatum ATCC 25586
Genome accession: NC_003454
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 441419 - 444013 bp
Length : 2595 bp
Strand : +
Note : -

DNA sequence :
ATGTTAGGAGGTTTTATTATGATGAATCCAAATCAATTTACAGAGAATACTATTTCTGCAATTAATTTAGCAGTAGATAT
TAGTAAAGGTAATATGCAACAAAGTATAAAACCAGAAGCTCTTGCTTTGGGATTACTTATGCAAAACAACGGATTAATTC
CAAGAGTAATAGAAAAAATGGGATTGAATTTACAATATATCATTTCTGAATTAGAAAAAGAAATGAATAATTATCCAAAA
GTTGAAGTGAAAGTTAGCAATGAAAATATTTCACTTGACCAAAAAACAAATTCTATACTAAATCGTGCAGAAAAAATTAT
GAATGAAATGGAAGATAGCTTTTTAAGTGTTGAACATATTTTTAAAGCTATGATAGAAGAAATGCCAATTTTCAAAAGAT
TTGGTATTAGTTTAGAAAAATACATGGAGGTATTGATGAATATAAGAGGAAACAGAAAAGTAGATAATCAAAATCCAGAA
GCAACTTATGAAGTTTTAGAAAAATATGCAAAAGATTTAGTTGAACTTGCCAGAGAAGGTAAGATAGACCCTATCATTGG
TAGAGATTCTGAAATCAGAAGAGCTATTCAAATAATTTCAAGAAGAACAAAAAATGACCCTATTTTAATTGGTGAACCTG
GAGTTGGTAAAACTGCAATAGTTGAAGGACTTGCTCAAAGAATATTAAATGGAGATGTTCCTGAAAGTCTAAAGAATAAA
AAAATATTCTCGCTTGATATGGGAGCTTTGGTTGCAGGTGCAAAATACAAAGGTGAATTTGAAGAAAGAATGAAAGGTGT
TTTAAAAGAAGTTGAAGAATCAAATGGAAATATCATTCTTTTCATAGATGAAATTCACACAATAGTTGGTGCTGGTAAAG
GAGAAGGTTCTCTTGATGCAGGAAATATGTTAAAACCTATGCTTGCAAGAGGTGAATTAAGAGTTATTGGTGCAACAACA
ATAGATGAATATAGAAAATATATTGAAAAAGATCCTGCACTTGAAAGAAGGTTCCAAACAATATTAGTCAATGAACCTAA
TGTTGATGATACTATTTCAATTTTAAGAGGTCTTAAAGATAAATTTGAAACTTATCATGGTGTTAGAATTACAGATACTG
CAATAGTTGAAGCTGCAACCCTTAGCCAAAGATATATAAGTGATAGAAAACTTCCAGATAAAGCTATTGACCTAATTGAT
GAAGCAGCTGCTATGATAAGAACAGAAATTGACTCTATGCCAGAAGAACTCGACCAATTGACAAGAAAGGCTTTACAATT
AGAAATTGAAATTAAGGCATTGGAAAAAGAAACTGATGATGCTTCTAAGGAAAGATTGAAAGTTATAGAAAAAGAATTAG
CTGAATTAAATGAAGAAAAGAAAGTTTTGACATCAAAATGGGAACTTGAAAAAGAAGATATTTCTAAAATAAAAAATATT
AAAAGAGAAATTGAAAATGTTAAACTTGAAATGGAAAAAGCAGAAAGAGAATATGACTTAACAAAATTATCTGAATTAAA
ATATGGTAAACTTGCAACTCTTGAAAAAGAATTACAAGAACAACAAAATAAGGTTGATAAAGATGGAAAAGAAAATTCTC
TATTAAAACAAGAAGTTACTGCTGATGAGATTGCAGATATTGTTTCAAGATGGACAGGTATTCCTGTATCAAAACTTACC
GAAACTAAAAAAGAAAAGATGTTACATCTTGAAGACCATATAAAAGAAAGAGTTAAAGGACAAGATGAAGCCATTAAATC
CGTTGCTGATACTATGCTTAGATCAGTTGCAGGTTTAAAAGATCCTAACAGACCTATGGGTTCATTTATATTCTTAGGAC
CTACTGGGGTTGGTAAAACATATCTTGCAAAAACTTTAGCATATAACCTATTTGATAGTGAAGATAATGTTGTCAGAATA
GATATGAGTGAATATATGGATAAGTTCTCAGTTACAAGACTTATAGGTGCACCCCCAGGATATGTTGGTTATGAAGAAGG
TGGACAACTTACAGAAGCTATAAGAACTAAACCTTATTCAGTAATATTGTTTGATGAAATTGAAAAGGCTCATCCTGATG
TATTTAATGTACTATTACAAGTTTTAGATGATGGTAGACTTACAGATGGGCAAGGAAGAATAGTGGATTTCAAAAACACT
TTAATTATAATGACATCTAATATAGGTAGCCATTTTATACTTGAAGATCCTAATCTTTCTGAAGATACGAGAGAAAAAGT
AGCAGATGAATTAAAAGCTAGATTTAAGCCAGAATTTTTAAATAGAATTGATGAAATAATCACTTTCAAGGCTTTAGATT
TACCAGCTATTAAAGAAATCGTAAAATTAAGTCTAAAAGACTTAGAAAACAAATTAAAACCTAAACACATTACACTTGAA
TTTTCTGATAAGATGGTTGATTACTTAGCTAACAATGCTTATGACCCTCACTATGGTGCAAGACCTCTAAGAAGATATAT
TCAAAGAGAAATTGAAACAAGTCTTGCTAAGAAAATTCTTGCAAATGAAGTACATGAAAAATCTAATGTCTTAATAGATT
TAGATAATAACCATATTGTTTTTAAAGAAGTATAA

Protein sequence :
MLGGFIMMNPNQFTENTISAINLAVDISKGNMQQSIKPEALALGLLMQNNGLIPRVIEKMGLNLQYIISELEKEMNNYPK
VEVKVSNENISLDQKTNSILNRAEKIMNEMEDSFLSVEHIFKAMIEEMPIFKRFGISLEKYMEVLMNIRGNRKVDNQNPE
ATYEVLEKYAKDLVELAREGKIDPIIGRDSEIRRAIQIISRRTKNDPILIGEPGVGKTAIVEGLAQRILNGDVPESLKNK
KIFSLDMGALVAGAKYKGEFEERMKGVLKEVEESNGNIILFIDEIHTIVGAGKGEGSLDAGNMLKPMLARGELRVIGATT
IDEYRKYIEKDPALERRFQTILVNEPNVDDTISILRGLKDKFETYHGVRITDTAIVEAATLSQRYISDRKLPDKAIDLID
EAAAMIRTEIDSMPEELDQLTRKALQLEIEIKALEKETDDASKERLKVIEKELAELNEEKKVLTSKWELEKEDISKIKNI
KREIENVKLEMEKAEREYDLTKLSELKYGKLATLEKELQEQQNKVDKDGKENSLLKQEVTADEIADIVSRWTGIPVSKLT
ETKKEKMLHLEDHIKERVKGQDEAIKSVADTMLRSVAGLKDPNRPMGSFIFLGPTGVGKTYLAKTLAYNLFDSEDNVVRI
DMSEYMDKFSVTRLIGAPPGYVGYEEGGQLTEAIRTKPYSVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRIVDFKNT
LIIMTSNIGSHFILEDPNLSEDTREKVADELKARFKPEFLNRIDEIITFKALDLPAIKEIVKLSLKDLENKLKPKHITLE
FSDKMVDYLANNAYDPHYGARPLRRYIQREIETSLAKKILANEVHEKSNVLIDLDNNHIVFKEV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-105 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
FN1941 NP_602741.1 ATP-dependent chaperone ClpB VFG2076 Protein 7e-116 41