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Name : FN1419 (FN1419) Accession : NP_604313.1 Strain : Fusobacterium nucleatum ATCC 25586 Genome accession: NC_003454 Putative virulence/resistance : Resistance Product : methionine gamma-lyase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 4.4.1.11 Position : 2080705 - 2081892 bp Length : 1188 bp Strand : + Note : catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine DNA sequence : ATGGAAATGAAAAAATCTGGTTTAGGAACAACTGCTATACATGCAGGAACTTTAAAAAATTTATATGGAACTCTTGCAAT GCCTATATATCAAACTTCTACTTTTATATTTGATTCAGCAGAACAAGGAGGAAGAAGATTTGCCCTTGAAGAAGCTGGAT ATATTTACACAAGACTAGGCAATCCTACAACAACAGTGTTAGAAAATAAAATTGCTGCTCTTGAAGAAGGTGAAGCTGGA ATAGCTATGTCATCTGGTATGGGAGCTATCTCTTCAACATTGTGGACTGTATTAAAAGCTGGAGATCATGTTGTTACAGA TAAAACTTTATATGGTTGTACTTTTGCTTTGATGAATCATGGACTTACAAGATTTGGAGTTGAAGTTACTTTTGTTGATA CTTCTAATTTAGAAGAAGTTAAAAATGCTATGAAAAAAAATACAAGAGTTGTTTATCTTGAAACTCCTGCCAATCCAAAT TTAAAAATAGTTGATTTAGAAGCTTTATCTAAAATTGCTCACACAAATCCAAATACTTTGGTTATAGTAGATAATACTTT TGCAACTCCATATATGCAAAAACCTTTAAAATTAGGTGTAGATATTGTTGTACACTCTGCAACTAAATATTTGAATGGAC ATGGAGATGTAATAGCAGGTCTTGTTGTAACAAGACAAGAACTTGCAGATCAAATCCGTTTTGTTGGATTAAAAGATATG ACAGGAGCTGTTTTAGGACCTCAAGAAGCATATTACATTATAAGAGGATTGAAAACATTTGAAATTCGTATGGAAAGACA CTGTAAAAATGCAAGAACTATTGTAGATTTCTTAAATAAACATCCAAAAGTTGAAAAAGTTTATTATCCTGGACTTGAGA CTCATCCTGGTTATGAAATAGCTAAAAAACAAATGAAAGATTTTGGAGCAATGATTTCATTTGAATTAAAAGGTGGCTTT GAAGCAGGTAAAACTTTATTAAATAATTTAAAACTTTGTTCATTAGCAGTTTCATTAGGAGATACTGAAACTCTTATTCA ACACCCAGCATCTATGACACACTCTCCTTATACAAAGGAAGAAAGAGAAGTTGCTGGAATCACTGATGGTTTAGTTAGAT TATCAGTTGGACTTGAAAATGTTGAAGATATTATAGCTGATTTAGAACAAGGACTAGAAAAAATTTAA Protein sequence : MEMKKSGLGTTAIHAGTLKNLYGTLAMPIYQTSTFIFDSAEQGGRRFALEEAGYIYTRLGNPTTTVLENKIAALEEGEAG IAMSSGMGAISSTLWTVLKAGDHVVTDKTLYGCTFALMNHGLTRFGVEVTFVDTSNLEEVKNAMKKNTRVVYLETPANPN LKIVDLEALSKIAHTNPNTLVIVDNTFATPYMQKPLKLGVDIVVHSATKYLNGHGDVIAGLVVTRQELADQIRFVGLKDM TGAVLGPQEAYYIIRGLKTFEIRMERHCKNARTIVDFLNKHPKVEKVYYPGLETHPGYEIAKKQMKDFGAMISFELKGGF EAGKTLLNNLKLCSLAVSLGDTETLIQHPASMTHSPYTKEEREVAGITDGLVRLSVGLENVEDIIADLEQGLEKI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 3e-61 | 44 |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 7e-67 | 42 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 5e-68 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| FN1419 | NP_604313.1 | methionine gamma-lyase | BAC0207 | Protein | 6e-103 | 55 |
