Gene Information

Name : hemC (FN0645)
Accession : NP_603542.1
Strain : Fusobacterium nucleatum ATCC 25586
Genome accession: NC_003454
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1301458 - 1302354 bp
Length : 897 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAAAAAAATATTATCATTGGAAGTAGAGGAAGCATACTAGCATTAGCACAAGCAAATCTTGTAAAAGATAGATTACA
AGGAAATTATCCTAATTTAAGTTTTGAGATAAAAGAAATAGTTACAAGTGGAGATAAAGATTTAAAATCAAATTGGGAAA
ATAGTGATATTTCTTTAAAAAGCTTTTTTACTAAAGAAATTGAACAAGAATTATTAGATGGAGAAATAGATATTGCAGTT
CATTCTATGAAAGATATGCCTGCTGTATCAGCTAAGAGTTTAATTTGTGGAGCAATTCCAGACAGAGAAGATCCAAGGGA
TGTATTAGTATCAAAAAATGGACTTTTAGTTACTTTACCTCAAGGAGCTAAAGTTGGTACAAGTTCACTAAGAAGAGCAA
TGAATTTAAAAACAGTGAGACCTGATTTTGAAATTAAACATTTAAGAGGGAATATACATACAAGACTTAAAAAATTAGAA
ACAGAAGACTATGATGCAATAGTTTTAGCTGCTGCTGGACTTAAAAGAACAGGTTTAGCAGATAAAATAACTGAATATCT
AAATGGAGAAGTATTTCCACCTGCACCTGCACAAGGCGTTCTATACATTCAATGTAGAGAAAACGACGAAGAAATAAAAG
AGATTTTAAAATCTATCCATAATGAAGCTATTGCAAAGATTGTTGAGATAGAAAGAGAATTTTCTAAAATATTTGATGGT
GGCTGTCATACTCCTATGGGGTGCTATTCTCAAGTAAATGGAGATAAAATAAAATTTACTGCTGTTTATTTAGATGAAGG
AAAACAAATAAGAGCTGTTGTTGAAGATGATTTAGCAAAGGGGAAAGAAATTGCATATATGGCAGCAGAAGAAATTAAGA
ATAAAATAGTTAAATAA

Protein sequence :
MKKNIIIGSRGSILALAQANLVKDRLQGNYPNLSFEIKEIVTSGDKDLKSNWENSDISLKSFFTKEIEQELLDGEIDIAV
HSMKDMPAVSAKSLICGAIPDREDPRDVLVSKNGLLVTLPQGAKVGTSSLRRAMNLKTVRPDFEIKHLRGNIHTRLKKLE
TEDYDAIVLAAAGLKRTGLADKITEYLNGEVFPPAPAQGVLYIQCRENDEEIKEILKSIHNEAIAKIVEIEREFSKIFDG
GCHTPMGCYSQVNGDKIKFTAVYLDEGKQIRAVVEDDLAKGKEIAYMAAEEIKNKIVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-45 41
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-45 41