Gene Information

Name : smpB (FN0609)
Accession : NP_603506.1
Strain : Fusobacterium nucleatum ATCC 25586
Genome accession: NC_003454
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1264401 - 1264847 bp
Length : 447 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGATAATTGCGAATAATAAGAAGGCTTTTTTTGATTACTTCATAGAAGAAAAATATGAAGCAGGAATTGAGTTAAAAGG
TAGTGAGGTAAAATCAATTAAAGCAGGAAAAGTTAGTATAAAAGAAGCTTTTGTTAGAATTATAAATGATGAAATATTCA
TAATGGGAATGTCAGTTGTTCCTTGGGAATTTGGAAGCGTTTATAATCCAGAAGAAAGAAGAGTTAGAAAATTACTTTTA
CATAGAAAAGAAATAAAAAAAATTCATGAAAAAGTAAAAATAAAAGGTTATACAATAGTTCCCTTAGATGTTCATTTATC
AAAGGGTTATGTAAAAATGCAAATTGCAATAGCAAAAGGTAAAAAGACATATGATAAGAGAGAAAGTATAGCTAAGAAAG
ATCAAGAGAGAAATTTAAAAAGAGAATTTAAAAATAATAATAGATAA

Protein sequence :
MIIANNKKAFFDYFIEEKYEAGIELKGSEVKSIKAGKVSIKEAFVRIINDEIFIMGMSVVPWEFGSVYNPEERRVRKLLL
HRKEIKKIHEKVKIKGYTIVPLDVHLSKGYVKMQIAIAKGKKTYDKRESIAKKDQERNLKREFKNNNR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 7e-20 42
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-23 41
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 9e-20 41