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Name : FN0454 (FN0454) Accession : NP_603351.1 Strain : Fusobacterium nucleatum ATCC 25586 Genome accession: NC_003454 Putative virulence/resistance : Virulence Product : aldehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : 1.2.1.22 Position : 1099607 - 1101082 bp Length : 1476 bp Strand : + Note : - DNA sequence : ATGGAGAATATATTAAAGAAATCATATAAAATGTTTATAAATGGGGAATGGATAGATTCAAGTAATGGAGTTATGGTAAA GTCTTATGCTCCTTACAACAATGAATTATTATCTGAATTTCCTGATGCAAGTGAAAGTGATATTGATTTTGCAATTAAAA GTGCAAAAGAAGCTTTTAAAACTTGGAGAAAGACAACAGTAAAAGAAAGAGCAAGAATTTTAAATAAAATTGCTGATATT ATAGATGAAAACAAGGATTTGTTAGCAACGGTTGAAACTATGGATAATGGTAAACCAATAAGAGAAACAAAGTTAGTAGA TATTCCACTGGCAGCAACTCATTTTAGATATTTTGCAGGATGTATTTTAGCAGATGAAGGACAAGCTACTGTATTAGATG AAAAATTTTTAAGTTTAATTTTAAGAGAACCTATAGGGGTTGTTGGGCAAATTATTCCTTGGAACTTTCCATTCTTAATG GCAGCTTGGAAGTTAGCACCAGCTCTTGCAGCAGGAGATACAGTTGTTTTAAAACCATCTAGTACAACAACATTAAGTTT ATTAGTTTTAATGGAACTTATTCAAGATGTAATTCCAAAAGGAGTTGTAAACTTAGTTACAGGAAAAGGAAGTACAGCAG GAGAATTCTTAAAGAATCACCCTGATTTAGATAAATTAGCTTTCACAGGTTCAACAGCAGTTGGTAGAGATATAGCTCTT GCAGCGGCAGAAAAATTAATTCCAGCAACTCTTGAATTAGGTGGAAAATCAGCAAATATTATTTTAGATGATGCTGATAT AGAAAAAGCTCTTGAAGGAGCTCAACTTGGGATACTATTTAACCAAGGACAAGTTTGTTGTGCAGGTTCAAGAATATTTG TACAAGAAGGAATATATGATGAGTTTATATCAAAACTTGTAAAGAAATTTGAAAATATTAAAATTGGAAACCCATTAGAC CCTACAACTATAATGGGAAGTCAAATAGATGCAAGACAAGTAAAAACTATTTTAGATTATGTTGAAATAGCTAAACAAGA AGGTGGAGTTATTTTAACAGGAGGAGTGAAATATACTGAAAATGGTTGTGACAAAGGAAATTTTGTAAGACCTACTTTAA TAACTAATGTTAATAATGGTTGTCGTGTTTCTCAAGAAGAAATTTTTGGACCAGTAGCTGTTGTAATTAAGTTTAAAACA GATGATGAGGTTATTGCACAAGCAAATGATAGTGAATATGGACTTGGAGGAGCAGTATTTACAAAAAATATCAATAGAGC TTTAAAACTTGCAAGAGAAATTCAAACAGGTAGAGTGTGGATAAATACTTATAATCAAATTCCAGAACATGCCCCATTTG GAGGATATAAAAAATCTGGTATAGGAAGAGAAACACATAAAGTAATCTTAGAACACTATACACAAATGAAAAATATCTTA ATTGATTTAGAAGAAGGAACTTCTGGATTATATTAA Protein sequence : MENILKKSYKMFINGEWIDSSNGVMVKSYAPYNNELLSEFPDASESDIDFAIKSAKEAFKTWRKTTVKERARILNKIADI IDENKDLLATVETMDNGKPIRETKLVDIPLAATHFRYFAGCILADEGQATVLDEKFLSLILREPIGVVGQIIPWNFPFLM AAWKLAPALAAGDTVVLKPSSTTTLSLLVLMELIQDVIPKGVVNLVTGKGSTAGEFLKNHPDLDKLAFTGSTAVGRDIAL AAAEKLIPATLELGGKSANIILDDADIEKALEGAQLGILFNQGQVCCAGSRIFVQEGIYDEFISKLVKKFENIKIGNPLD PTTIMGSQIDARQVKTILDYVEIAKQEGGVILTGGVKYTENGCDKGNFVRPTLITNVNNGCRVSQEEIFGPVAVVIKFKT DDEVIAQANDSEYGLGGAVFTKNINRALKLAREIQTGRVWINTYNQIPEHAPFGGYKKSGIGRETHKVILEHYTQMKNIL IDLEEGTSGLY |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 1e-90 | 52 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 7e-95 | 49 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 7e-95 | 49 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 7e-95 | 49 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 2e-94 | 49 |
| hpaE | AAO17179.1 | HpaE | Not tested | tcd island | Protein | 5e-71 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| FN0454 | NP_603351.1 | aldehyde dehydrogenase | VFG0082 | Protein | 4e-91 | 52 |
