Gene Information

Name : thyA (NCgl0810)
Accession : NP_600073.1
Strain : Corynebacterium glutamicum ATCC 13032
Genome accession: NC_003450
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 898431 - 899231 bp
Length : 801 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGACTGTTCCAACGCCTTATGAAGACCTTCTTCGGAAGATTGCTGAAGAAGGGTCCCACAAGGACGACCGCACCGGCAC
CGGCACTACTTCTTTATTCGGACAACAAATCCGCTTTGATCTCAATGAAGGTTTTCCCCTTCTGACCACCAAGAAGGTCC
ATTTCCACTCTGTTGTGGGTGAGCTTTTGTGGTTCCTTCAGGGGGATTCCAACGTCAAATGGCTGCAGGATAACAACATC
CGCATTTGGAATGAATGGGCAGATGAGGACGGCGAGCTGGGCCCTGTTTATGGTGTCCAGTGGCGTTCTTGGCCAACCCC
TGATGGTCGTCACATTGACCAGATCTCAGGTGCTTTAGAAACTCTGCGAAACAACCCTGATTCACGTCGCAATATTGTCT
CGGCGTGGAATGTTTCCGAGCTTGAAAACATGGCTCTTCCCCCTTGTCACTTGCTTTTCCAGCTCTATGTCGCCGATGGC
AAACTGTCTTGCCAGCTCTACCAGCGTTCTGCGGACATGTTCCTGGGTGTGCCTTTCAACATCGCATCTTATGCACTGCT
CACCCACATGTTTGCCCAGCAGGCAGGCTTGGAAGTCGGCGAGTTCATTTGGACTGGCGGCGACTGCCACATTTATGACA
ACCACAAGGAACAGGTCGCGGAGCAGCTGAGCCGCGAAGCTCGCCCCTACCCCACCTTGGAGCTCAACAAGGCAGCGTCC
ATGTTTGAGTACAGCTTCGATGACATCACCGTGTCCGGCTACGATCCACACCCATTGATCCGCGGCAAGGTCGCCGTATG
A

Protein sequence :
MTVPTPYEDLLRKIAEEGSHKDDRTGTGTTSLFGQQIRFDLNEGFPLLTTKKVHFHSVVGELLWFLQGDSNVKWLQDNNI
RIWNEWADEDGELGPVYGVQWRSWPTPDGRHIDQISGALETLRNNPDSRRNIVSAWNVSELENMALPPCHLLFQLYVADG
KLSCQLYQRSADMFLGVPFNIASYALLTHMFAQQAGLEVGEFIWTGGDCHIYDNHKEQVAEQLSREARPYPTLELNKAAS
MFEYSFDDITVSGYDPHPLIRGKVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 3e-110 85