Gene Information

Name : smpB (NCgl0770)
Accession : NP_600033.1
Strain : Corynebacterium glutamicum ATCC 13032
Genome accession: NC_003450
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 846137 - 846631 bp
Length : 495 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCCAAGAAGAAAAAGAAAGTCGACGAAAACAACTCAGTTCTCGCGACCAATCGCAAGGCCCGCCATGACTACCACAT
CATTGATACGTGGGAGGCGGGCGTGGTGCTCTTAGGCACCGAAATCAAATCACTGCGCGAAGGTAAGGTATCCCTCGTGG
ATTCCTTTGCCACCATTGATAACGGAGAAATCTGGCTTCAGCATCTCCACATCCCGCAGTATTCCATGGGCTCCTGGACA
AACCACACGCCCAAGCGCACCCGCAAACTTTTGCTGCACCGCAACGAGATTGATTCCCTGATGGGTAAAGTCCGCGACGG
CAACCGCACGTTGGTTCCGCTCAAGCTTTACCTCAAAAACGGTCGCGTCAAACTCGAACTCGGACTCGCACAAGGTAAGC
AGGATTACGACAAGCGCCAAGATATCAAGCGTCGCACCGAAGAACGCGAAGTCACCCGTGAGCTCGGCCGTCGCATTAAG
GGAATCAACGCGTAA

Protein sequence :
MAKKKKKVDENNSVLATNRKARHDYHIIDTWEAGVVLLGTEIKSLREGKVSLVDSFATIDNGEIWLQHLHIPQYSMGSWT
NHTPKRTRKLLLHRNEIDSLMGKVRDGNRTLVPLKLYLKNGRVKLELGLAQGKQDYDKRQDIKRRTEEREVTRELGRRIK
GINA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 2e-44 73
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-31 57
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 6e-20 42