Gene Information

Name : leuS (NCgl2915)
Accession : NP_602213.1
Strain : Corynebacterium glutamicum ATCC 13032
Genome accession: NC_003450
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3219776 - 3222634 bp
Length : 2859 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACTAACCCGAGCGAAGGCACCACTCCCCTGGCGTTCCGTTATACCCCGGAACTCGCCAACAAGATCGAAGGTGAGTG
GCAGAATTACTGGACTGACAACGGCACATTCAACGCACCCAACCCAGTGGGTGATTTAGCGCCTGCGGACGGTAAAGCAC
TTCCTGAGGACAAGCTCTTTGTCCAGGATATGTTCCCGTACCCATCCGGAGCTGGCCTGCACGTAGGCCACCCACTCGGT
TACATCGCAACGGATGTTTTCGCCCGCTACAACCGCATGCTGGGCAAGAACGTTCTGCACACCTTGGGCTATGACGCCTT
CGGACTGCCAGCAGAGCAGTACGCGATCCAAACCGGTACACACCCACGCACCACCACCATGGCCAACATTGAGAACATGA
AGCGCCAGCTCGGTGCGCTGGGTCTTGGCCATGATTCCCGTCGTGCGGTGGCCACCACGGATCCTGAGTTCTACAAGTGG
ACTCAGTGGATCTTCCTGCAGATTTTCAATTCGTGGTTCGATGCAGAGCAGCAGAAGGCACGTCCCATCAGTGAGCTGAT
TCCGTTGCTGGAGTCCGGCGAGCTGAAGACTAAGGACGGGGCGGATTACAACGCGCTGGGAGACGTCGAAAAGCAAAAAG
CGGTGGATGACTACCGCCTTGTTTATCGCTCGAACTCCACCGTGAACTGGTGCCCAGGCTTGGGCACCGTGTTGGCAAAC
GAGGAAGTGACCGCGGACGGCCGTTCCGAGCGTGGCAATTTCCCTGTTTTCCGTAAGAATTTGTCCCAGTGGATGATGCG
CATTACCGCGTACTCGGATCGTCTGATCGATGATCTGGAGCTGCTCGATTGGACTGAGAAGGTCAAGTCCATGCAGCGTA
ACTGGATTGGCCGTTCCCGCGGCGCTGAAGTTGATTTCAGTGCAGAGGGCGAAACCGTCACCGTGTTTACCACCCGCCCA
GATACTCTGTTCGGCGCGACCTACATGGTTCTTGCACCTGAGCATGAGCTGGTCGACGTGCTGCTGGAGAAGGCTGGTTC
CTACGAGGGCGTTGATGCCCGTTGGACCAATGGCCAGGCGAGCCCTGCGGAAGCTGTCGCTGCATACCGCGCCTCCATCG
CCGCGAAGTCCGACCTGGAGCGTCAGGAAAACAAGGAAAAGACCGGCGTCTTCCTGGGCGTTTACGCGACCAACCCAGTC
AACGGCGATCAGATCACAGTGTTCATCGCTGACTACGTTCTGACCGGCTACGGCACCGGCGCCATCATGGCGGTTCCTGC
TCACGACGAGCGCGACTACGAATTCGCCACCGTTTTGGGTCTGCCTATCAAGGAAGTTGTCGCAGGTGGCAACATCGAAG
AGGCTGCTTTCACCGAATCTGGCGAAGCAGTCAACTCTGCGAACGACAACGGCCTGGATATCAACGGCCTTGCCAAGGAT
GAGGCTATTGCCAAGACCATCGAATGGTTGGAAGAAAAGGAACTTGGCCGCGGCACCATCCAGTACAAGCTGCGCGACTG
GCTGTTCGCTCGCCAGCGTTACTGGGGCGAGCCTTTCCCAATCGTCTACGACGAAAACGGCCAAGCACATGCTCTGCCAG
ACTCCATGCTTCCAGTCGAGCTGCCAGAGGTAGAGGACTACAAGCCTGTCTCCTTCGACCCTGAAGACGCAGACTCCGAG
CCTTCCCCACCACTGGCTAAGGCCCGCGAATGGGTTGAGGTGGAACTCGATCTCGGCGATGGCAAGAAGAAGTACACCCG
CGACACCAACGTCATGCCACAGTGGGCAGGTTCCTCCTGGTACCAGCTGCGCTACGTCGATCCAAGCAACGATGAGCAGT
TCTGCAACATCGAAAATGAACGCTACTGGACCGGCCCACGCCCAGAAACCCACGGACCAAACGATCCAGGCGGCGTAGAC
CTCTACGTCGGTGGCGTCGAGCACGCAGTTCTCCACCTGCTCTACGCACGTTTCTGGCACAAGGTCCTCTTCGACCTGGG
CCACGTCTCCTCCAAGGAGCCATACCGTCGCCTGTACAACCAGGGCTACATCCAGGCCTTCGCCTACACCGATTCCCGTG
GCGTCTACGTGCCTGCCGATGATGTCGAAGAGAAGGACGGAAAGTTCTTCTACCAGGGCGAAGAAGTCAACCAGGAATAC
GGAAAGATGGGCAAGTCCCTGAAGAACGCCGTTGCCCCAGACGATATCTGCAACAACTTCGGTGCTGACACCCTGCGCGT
TTACGAGATGGCCATGGGACCTTTGGACACCTCCCGTCCATGGGCAACCAAGGACGTCGTCGGTGCGCAGCGCTTCCTCC
AGCGTCTGTGGCGTCTCGTCGTCGATGAAAACACCGGCGAAGTGCTCACTCGCGATGAAGTCCTCACCGACGATGACAAC
AAGCAACTGCACCGCACCATCGCAGGCGTCCGCGACGACTACACCAACTTGCGCGTTAACACCGTGGTTGCCAAGCTCAT
CGAATACGTCAACTACCTGACCAAAACATACCCAGACACCATCCCAGCTGGCGCAGTCCTGCCACTGATCGTCATGGTCT
CCCCTATCGCACCACACATCGCGGAGGAACTCTGGAAGAAGCTCGGCCACGACGACACCGTCACCTACGAACCATTCCCC
ACCTTTGAGGAAAAATGGCTCACCGACGATGAAATCGAACTGCCAGTCCAGGTCAACGGCAAGGTCCGCGGTCGCATCAC
CGTTGCAGCCGACGCCAGCCAGGAGCAGGTCATCGAGGCAGCGCTTGCCGACGAGAAGGTGCAGGAGCAAATCTCCGGCA
AGAACCTGATCAAGCAGATCGTTGTTCCAGGACGCATGGTTAACCTTGTGGTGAAGTAA

Protein sequence :
MTNPSEGTTPLAFRYTPELANKIEGEWQNYWTDNGTFNAPNPVGDLAPADGKALPEDKLFVQDMFPYPSGAGLHVGHPLG
YIATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGLGHDSRRAVATTDPEFYKW
TQWIFLQIFNSWFDAEQQKARPISELIPLLESGELKTKDGADYNALGDVEKQKAVDDYRLVYRSNSTVNWCPGLGTVLAN
EEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDLELLDWTEKVKSMQRNWIGRSRGAEVDFSAEGETVTVFTTRP
DTLFGATYMVLAPEHELVDVLLEKAGSYEGVDARWTNGQASPAEAVAAYRASIAAKSDLERQENKEKTGVFLGVYATNPV
NGDQITVFIADYVLTGYGTGAIMAVPAHDERDYEFATVLGLPIKEVVAGGNIEEAAFTESGEAVNSANDNGLDINGLAKD
EAIAKTIEWLEEKELGRGTIQYKLRDWLFARQRYWGEPFPIVYDENGQAHALPDSMLPVELPEVEDYKPVSFDPEDADSE
PSPPLAKAREWVEVELDLGDGKKKYTRDTNVMPQWAGSSWYQLRYVDPSNDEQFCNIENERYWTGPRPETHGPNDPGGVD
LYVGGVEHAVLHLLYARFWHKVLFDLGHVSSKEPYRRLYNQGYIQAFAYTDSRGVYVPADDVEEKDGKFFYQGEEVNQEY
GKMGKSLKNAVAPDDICNNFGADTLRVYEMAMGPLDTSRPWATKDVVGAQRFLQRLWRLVVDENTGEVLTRDEVLTDDDN
KQLHRTIAGVRDDYTNLRVNTVVAKLIEYVNYLTKTYPDTIPAGAVLPLIVMVSPIAPHIAEELWKKLGHDDTVTYEPFP
TFEEKWLTDDEIELPVQVNGKVRGRITVAADASQEQVIEAALADEKVQEQISGKNLIKQIVVPGRMVNLVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 8e-158 49